(Q28591548)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Aberrant growth and differentiation of oligodendrocyte progenitors in neurofibromatosis type 1 mutants (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

GOA release 2020-03-11

1 reference

Saikumar Karyala

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Nancy Ratner

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Michael R Bennett

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Tilat A Rizvi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Randall D McKinnon

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

language of work or name

English

0 references

publication date

1 August 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

published in

Journal of Neuroscience

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

23

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

issue

18

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

page(s)

7207-7217

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

Stem cells in the adult mammalian central nervous system

6 November 2019

cites work

1 reference

12 December 2020

The Nf1 tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited by fibroblasts

1 reference

12 December 2020

Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation

1 reference

12 December 2020

Multipotent and restricted precursors in the central nervous system

1 reference

12 December 2020

Cognitive impairment in neurofibromatosis type 1.

1 reference

12 December 2020

Lineage-restricted neural precursors can be isolated from both the mouse neural tube and cultured ES cells

1 reference

12 December 2020

On the lysosomal degradation of neurofibromin and its phosphorylation in cultured melanocytes

1 reference

12 December 2020

Mechanisms of oligodendrocyte commitment in the vertebrate CNS.

1 reference

12 December 2020

Nf1 and Gmcsf interact in myeloid leukemogenesis

1 reference

12 December 2020

A neurofibromatosis-1-regulated pathway is required for learning in Drosophila

1 reference

12 December 2020

Farnesyltransferase inhibitors: antineoplastic mechanism and clinical prospects

1 reference

12 December 2020

Elevated levels of the chemokine GRO-1 correlate with elevated oligodendrocyte progenitor proliferation in the jimpy mutant

1 reference

12 December 2020

Thalamic involvement in neurofibromatosis type 1: evaluation with proton magnetic resonance spectroscopic imaging.

1 reference

12 December 2020

GFAP-positive and myelin marker-positive glia in normal and pathologic environments

1 reference

12 December 2020

Neurofibromin negatively regulates neurotrophin signaling through p21ras in embryonic sensory neurons

1 reference

12 December 2020

Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts

1 reference

12 December 2020

Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas.

1 reference

12 December 2020

NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions.

1 reference

12 December 2020

Distinct roles for PI3K in proliferation and survival of oligodendrocyte progenitor cells

1 reference

12 December 2020

NF1 tumor suppressor gene function: narrowing the GAP

1 reference

12 December 2020

Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes

1 reference

12 December 2020

1 reference

12 December 2020

Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

1 reference

12 December 2020

Increased brain apparent diffusion coefficient in children with neurofibromatosis type 1.

1 reference

12 December 2020

Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord.

1 reference

12 December 2020

Prospective evaluation of the brain in asymptomatic children with neurofibromatosis type 1: relationship of macrocephaly to T1 relaxation changes and structural brain abnormalities.

1 reference

12 December 2020

Embryonic-derived glial-restricted precursor cells (GRP cells) can differentiate into astrocytes and oligodendrocytes in vivo

1 reference

12 December 2020

Loss of NF1 alleles distinguish sporadic from NF1-associated pilocytic astrocytomas.

1 reference

12 December 2020

Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube

1 reference

12 December 2020

The tripotential glial-restricted precursor (GRP) cell and glial development in the spinal cord: generation of bipotential oligodendrocyte-type-2 astrocyte progenitor cells and dorsal-ventral differences in GRP cell function.

1 reference

12 December 2020

Neurofibromin regulates G protein-stimulated adenylyl cyclase activity

1 reference

12 December 2020

Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1

1 reference

12 December 2020

The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification.

1 reference

12 December 2020

Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection

1 reference

12 December 2020

GTPase activating proteins: critical regulators of intracellular signaling

1 reference

12 December 2020

Molecular mechanisms controlling cortical gliogenesis

1 reference

12 December 2020

An 'oligarchy' rules neural development

1 reference

12 December 2020

Differentiation of proliferated NG2-positive glial progenitor cells in a remyelinating lesion

1 reference

12 December 2020

Absence of fibroblast growth factor 2 promotes oligodendroglial repopulation of demyelinated white matter.

1 reference

12 December 2020

PDGF and FGF2 regulate oligodendrocyte progenitor responses to demyelination

1 reference

12 December 2020

Fibroblast growth factor receptor 3 signaling regulates the onset of oligodendrocyte terminal differentiation

1 reference

12 December 2020

Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons

1 reference

12 December 2020

Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development

1 reference

12 December 2020

Effects of several growth factors on cultured neurofibroma cells

1 reference

12 December 2020

The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes

1 reference

12 December 2020

CG-4, a new bipotential glial cell line from rat brain, is capable of differentiating in vitro into either mature oligodendrocytes or type-2 astrocytes

1 reference

12 December 2020

FGF modulates the PDGF-driven pathway of oligodendrocyte development.

1 reference

12 December 2020

Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells

1 reference

12 December 2020

Two proliferative stages of the oligodendrocyte lineage (A2B5+O4- and O4+GalC-) under different mitogenic control

1 reference

12 December 2020

In vivo analysis of glial cell phenotypes during a viral demyelinating disease in mice

1 reference

12 December 2020

Identification of an adult-specific glial progenitor cell.

1 reference

12 December 2020

Monoclonal antibody to a plasma membrane antigen of neurons

1 reference

12 December 2020

Induced differentiation of clonal rat nerve and glial cells.

1 reference

12 December 2020

Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system

1 reference

12 December 2020

A small step for the cell, a giant leap for mankind: a hypothesis of neocortical expansion during evolution

1 reference

12 December 2020

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

1 reference

12 December 2020

Neurofibromin Expression and Astrogliosis in Neurofibromatosis (Type 1) Brains

1 reference

12 December 2020

Schwann cells from neurofibromin deficient mice exhibit activation of p21ras, inhibition of cell proliferation and morphological changes

1 reference

12 December 2020

Farnesyltransferase inhibitors block the neurofibromatosis type I (NF1) malignant phenotype

1 reference

12 December 2020

Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons

1 reference

12 December 2020

Apoptosis occurs in the oligodendroglial lineage, and is prevented by basic fibroblast growth factor

1 reference

12 December 2020

Neurofibromatosis type 1: pathologic substrate of high-signal-intensity foci in the brain

1 reference

12 December 2020

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

1 reference

12 December 2020

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

1 reference

12 December 2020

Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function

1 reference

12 December 2020

Neurofibromin is enriched in the endoplasmic reticulum of CNS neurons.

1 reference

12 December 2020

Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras

1 reference

12 December 2020

Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia

1 reference

12 December 2020

Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells

1 reference

12 December 2020

Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival

1 reference

12 December 2020

Increased expression of the neurofibromatosis 1 (NF1) gene product, neurofibromin, in astrocytes in response to cerebral ischemia

1 reference

12 December 2020

Transplantation of Genetically Engineered Primary Cells for the Analysis of Gene Function in CNS Development

1 reference

12 December 2020

Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase

1 reference

12 December 2020

Optic pathway gliomas in children with neurofibromatosis 1: consensus statement from the NF1 Optic Pathway Glioma Task Force.

1 reference

12 December 2020

Post-transcriptional regulation of neurofibromin level in cultured human melanocytes in response to growth factors

1 reference

12 December 2020

A mouse model for the learning and memory deficits associated with neurofibromatosis type I

1 reference

12 December 2020

Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides

1 reference

12 December 2020

Neuroepithelial stem cells from the embryonic spinal cord: isolation, characterization, and clonal analysis

1 reference

12 December 2020

Glial-restricted precursors are derived from multipotent neuroepithelial stem cells

1 reference

12 December 2020

Transplanted oligodendrocyte progenitor cells expressing a dominant-negative FGF receptor transgene fail to migrate in vivo.

1 reference

12 December 2020

Inhibitors of prenyl transferases.

1 reference

12 December 2020

A tripotential glial precursor cell is present in the developing spinal cord

1 reference

12 December 2020

Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines

1 reference

12 December 2020

In vivo proliferation of oligodendrocyte progenitors expressing PDGFalphaR during early remyelination

1 reference

12 December 2020

Region-specific astrogliosis in brains of mice heterozygous for mutations in the neurofibromatosis type 1 (Nf1) tumor suppressor

1 reference

12 December 2020

10.1523/JNEUROSCI.23-18-07207.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904481%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

2 references

31 January 2017