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Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
11246230
retrieved
24 January 2017
title
Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes
(English)
1 reference
stated in
PubMed
PubMed ID
11246230
retrieved
24 January 2017
main subject
astrocyte
0 references
Neurofibromin 1
1 reference
stated in
GOA release 2020-03-11
Transformation related protein 53
1 reference
stated in
GOA release 2020-03-11
RB transcriptional corepressor 1
1 reference
stated in
GOA release 2020-03-11
heterozygosity
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based on heuristic
inferred from title
author name string
M. L. Bajenaru
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
11246230
retrieved
24 January 2017
J. Donahoe
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2
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stated in
PubMed
PubMed ID
11246230
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24 January 2017
T. Corral
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3
1 reference
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PubMed
PubMed ID
11246230
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24 January 2017
K. M. Reilly
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4
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PubMed
PubMed ID
11246230
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24 January 2017
S. Brophy
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5
1 reference
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PubMed
PubMed ID
11246230
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24 January 2017
A. Pellicer
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6
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PubMed
PubMed ID
11246230
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24 January 2017
D. H. Gutmann
series ordinal
7
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PubMed
PubMed ID
11246230
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24 January 2017
publication date
15 March 2001
1 reference
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PubMed
PubMed ID
11246230
retrieved
24 January 2017
published in
Glia
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PubMed
PubMed ID
11246230
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24 January 2017
volume
33
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PubMed
PubMed ID
11246230
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24 January 2017
page(s)
314–323
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PubMed
PubMed ID
11246230
retrieved
24 January 2017
issue
4
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PubMed
PubMed ID
11246230
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24 January 2017
cites work
The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins
1 reference
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Crossref
reference URL
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retrieved
21 January 2018
Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Regulators and Effectors of ras Proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Mouse models of tumor development in neurofibromatosis type 1
1 reference
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Crossref
reference URL
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retrieved
21 January 2018
Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis
1 reference
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Crossref
reference URL
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retrieved
21 January 2018
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
The murine gene p27Kip1 is haplo-insufficient for tumour suppression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Proliferation of human malignant astrocytomas is dependent on Ras activation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
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21 January 2018
Precocious puberty in children with neurofibromatosis type 1.
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Crossref
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21 January 2018
Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
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21 January 2018
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo
1 reference
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Crossref
reference URL
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retrieved
21 January 2018
Effects of an Rb mutation in the mouse
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Tumour predisposition in mice heterozygous for a targeted mutation in Nf1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
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21 January 2018
Natural history of optic pathway tumors in children with neurofibromatosis type 1: a longitudinal study.
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Crossref
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21 January 2018
Optic pathway gliomas in children with neurofibromatosis 1: consensus statement from the NF1 Optic Pathway Glioma Task Force.
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Crossref
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21 January 2018
NF1 inactivation cooperates with N-ras in in vivo lymphogenesis activating Erk by a mechanism independent of its Ras-GTPase accelerating activity
1 reference
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Crossref
reference URL
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retrieved
21 January 2018
The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21
1 reference
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Crossref
reference URL
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21 January 2018
Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis
1 reference
stated in
Crossref
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retrieved
21 January 2018
Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation
1 reference
stated in
Crossref
reference URL
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21 January 2018
The management of brainstem gliomas in patients with neurofibromatosis 1.
1 reference
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Crossref
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retrieved
21 January 2018
Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Mouse tumor model for neurofibromatosis type 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-1136%2820010315%2933%3A4%3C314%3A%3AAID-GLIA1030%3E3.0.CO%3B2-Q
retrieved
21 January 2018
Identifiers
DOI
10.1002/1098-1136(20010315)33:4<314::AID-GLIA1030>3.0.CO;2-Q
0 references
PubMed ID
11246230
1 reference
stated in
PubMed
PubMed ID
11246230
retrieved
24 January 2017
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