(Q37640041)

21 August 2017

Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma (English)

1 reference

21 August 2017

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Zeev Ronai

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

M Scortegagna

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

C Ruller

2

1 reference

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13 June 2020

Y Feng

3

1 reference

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13 June 2020

R Lazova

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

H Kluger

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

S K De

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

R Rickert

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

M Pellecchia

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

M Bosenberg

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

16 September 2013

1 reference

21 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

4330-4339

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

13 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3955742/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3955742

based on heuristic

inferred from PubMed Central ID database lookup

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3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner

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23 August 2017

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Structure-based design of potent and selective 3-phosphoinositide-dependent kinase-1 (PDK1) inhibitors

23 August 2017

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Genetic and Pharmacological Inhibition of PDK1 in Cancer Cells: CHARACTERIZATION OF A SELECTIVE ALLOSTERIC KINASE INHIBITOR

23 August 2017

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23 August 2017

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23 August 2017

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PDK1: the major transducer of PI 3-kinase actions

23 August 2017

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c-Jun regulates phosphoinositide-dependent kinase 1 transcription: implication for Akt and protein kinase C activities and melanoma tumorigenesis

23 August 2017

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3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma

23 August 2017

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AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer

23 August 2017

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Phosphatidylinositol-3-kinase as a therapeutic target in melanoma

23 August 2017

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Dynamic FoxO transcription factors

23 August 2017

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Rewired ERK-JNK signaling pathways in melanoma

23 August 2017

1 reference

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

23 August 2017

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RACK1 mediates activation of JNK by protein kinase C [corrected].

23 August 2017

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The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling

23 August 2017

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Bioconductor: open software development for computational biology and bioinformatics

23 August 2017

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p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1

23 August 2017

1 reference

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PDK1, the master regulator of AGC kinase signal transduction

23 August 2017

1 reference

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Essential role of PDK1 in regulating cell size and development in mice

23 August 2017

1 reference

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Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

23 August 2017

1 reference

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Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors

23 August 2017

1 reference

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Mechanisms of intrinsic and acquired resistance to kinase-targeted therapies

6 September 2017

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Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

6 September 2017

1 reference

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Genomic alterations in lung adenocarcinomas detected by multicolor fluorescence in situ hybridization and comparative genomic hybridization

14 September 2017

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The 16p13.3 (PDPK1) Genomic Gain in Prostate Cancer: A Potential Role in Disease Progression

14 September 2017

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Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

25 June 2018

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Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer

25 June 2018

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PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models.

1 September 2018

1 reference

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Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1.

1 September 2018

1 reference

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Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice

1 September 2018

1 reference

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Cracking the system: melanoma complexity demands new therapeutic approaches

1 September 2018

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Crossref

https://api.crossref.org/works/10.1038%2FONC.2013.383

Characterization of melanocyte-specific inducible Cre recombinase transgenic mice

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2013.383

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.383

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

24037523

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037523%20AND%20SRC:MED&resulttype=core&format=json