(Q37641127)

21 August 2017

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title

Hsp90 inhibitors as promising agents for radiotherapy (English)

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adaptive radiation therapy

21 August 2017

main subject

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Hsp90 inhibitors

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ChEBI release 2020-05-28

Vladimir L Gabai

3

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author name string

Alexander E Kabakov

series ordinal

1

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21 August 2017

Vladimir A Kudryavtsev

series ordinal

2

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21 August 2017

publication date

28 November 2009

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Journal of Molecular Medicine

21 August 2017

published in

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21 August 2017

volume

88

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21 August 2017

issue

3

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21 August 2017

page(s)

241-247

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Radiosensitization of human vascular endothelial cells through Hsp90 inhibition with 17-N-allilamino-17-demethoxygeldanamycin

21 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS00109-009-0562-0

ErbB3 expression predicts tumor cell radiosensitization induced by Hsp90 inhibition

21 January 2018

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12 December 2020

Inhibition of homologous recombination repair in irradiated tumor cells pretreated with Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin

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12 December 2020

Tumor response to radiotherapy regulated by endothelial cell apoptosis

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12 December 2020

Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.

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12 December 2020

Increase of P-glycoprotein-mediated drug resistance by hsp 90 beta.

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12 December 2020

Targeting heat shock protein 90 overrides the resistance of lung cancer cells by blocking radiation-induced stabilization of hypoxia-inducible factor-1alpha.

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12 December 2020

An experimental study on the antitumor effect of 131I-17-AAG in vitro and in vivo

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12 December 2020

Synthesis of (131)I-labeled-[(131)I]iodo-17-allylamino-17-demethoxy geldanamycin ([(131)I]iodo-17-AAG) and its biodistribution in mice

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12 December 2020

Inhibition of hsp90 compromises the DNA damage response to radiation

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12 December 2020

Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex

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12 December 2020

Combination treatment with 17-N-allylamino-17-demethoxy geldanamycin and acute irradiation produces supra-additive growth suppression in human prostate carcinoma spheroids.

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12 December 2020

Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding agents.

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12 December 2020

Heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin potentiates the radiation response of tumor cells grown as monolayer cultures and spheroids by inducing apoptosis

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12 December 2020

Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells

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12 December 2020

Geldanamycin, an inhibitor of Hsp90, sensitizes human tumour cells to radiation

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12 December 2020

HSP90 inhibitor, DMAG, synergizes with radiation of lung cancer cells by interfering with base excision and ATM-mediated DNA repair

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12 December 2020

Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin

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12 December 2020

Preferential sensitization of tumor cells to radiation by heat shock protein 90 inhibitor geldanamycin

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12 December 2020

BIIB021, a novel Hsp90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy

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12 December 2020

Combined inhibition of extracellular signal-regulated kinases and HSP90 sensitizes human colon carcinoma cells to ionizing radiation

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12 December 2020

Enhancement radiosensitization of breast cancer cells by deguelin

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12 December 2020

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

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12 December 2020

In vitro combined modality treatment of prostate carcinoma cells with 17-(allylamino)-17-demethoxygeldanamycin and ionizing radiation

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12 December 2020

Heat shock protein 90 (Hsp90) chaperone complex inhibitor, radicicol, potentiated radiation-induced cell killing in a hormone-sensitive prostate cancer cell line through degradation of the androgen receptor

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12 December 2020

HSP90 inhibitors: multi-targeted antitumor effects and novel combinatorial therapeutic approaches in cancer therapy

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12 December 2020

P53-dependent radiosensitizing effects of Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin on human oral squamous cell carcinoma cell lines

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12 December 2020

Synergistic activity of imatinib and 17-AAG in imatinib-resistant CML cells overexpressing BCR-ABL--Inhibition of P-glycoprotein function by 17-AAG.

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12 December 2020

Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin

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12 December 2020

Enhanced cell killing induced by the combination of radiation and the heat shock protein 90 inhibitor 17-allylamino-17- demethoxygeldanamycin: a multitarget approach to radiosensitization

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12 December 2020

Epigenetic modulation of radiation response in human cancer cells with activated EGFR or HER-2 signaling: potential role of histone deacetylase 6.

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12 December 2020

Novel targeted radiosensitisers in cancer treatment

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12 December 2020

10.1007/S00109-009-0562-0

Identifiers

DOI

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21 August 2017

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