(Q37657502)

21 August 2017

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title

Adiponectin in health and diseases: from metabolic syndrome to tissue regeneration (English)

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21 August 2017

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1

Paola Chiarugi

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21 August 2017

Tania Fiaschi

2

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21 August 2017

language of work or name

English

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publication date

1 February 2010

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Expert Opinion on Therapeutic Targets

21 August 2017

published in

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21 August 2017

volume

14

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21 August 2017

issue

2

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21 August 2017

page(s)

193-206

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Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

AdipoQ is a novel adipose-specific gene dysregulated in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin and protection against type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Plasma adiponectin levels and risk of myocardial infarction in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Increased oxidative stress in obesity and its impact on metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Physiological, pharmacological, and nutritional regulation of circulating adiponectin concentrations in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin, the controversial hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Relationship between IL-6, leptin and adiponectin and variables of fibrinolysis in overweight and obese hypertensive patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin: more than just another fat cell hormone?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin and adiponectin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin and its receptors are expressed in bone-forming cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Expression and regulation of adiponectin and receptor in human and rat placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Induction of adiponectin in skeletal muscle of type 2 diabetic mice: In vivo and in vitro studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin is expressed by skeletal muscle fibers and influences muscle phenotype and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Hypoxia inducible factor-1 upregulates adiponectin in diabetic mouse hearts and attenuates post-ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin is synthesized and secreted by human and murine cardiomyocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Regulation of pituitary cell function by adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Globular adiponectin induces differentiation and fusion of skeletal muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

The metabolism of isoforms of human adiponectin: studies in human subjects and in experimental animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Post-translational modifications of adiponectin: mechanisms and functional implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Identification and adipocyte differentiation-dependent expression of the unique disialic acid residue in an adipose tissue-specific glycoprotein, adipo Q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Redox-dependent and ligand-independent trans-activation of insulin receptor by globular adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin, the missing link in insulin resistance and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin blocks interleukin-18-mediated endothelial cell death via APPL1-dependent AMP-activated protein kinase (AMPK) activation and IKK/NF-kappaB/PTEN suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

AdipoR1 mediates the anorexigenic and insulin/leptin-like actions of adiponectin in the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

APPL1: role in adiponectin signaling and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin stimulates production of nitric oxide in vascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Protective vascular and myocardial effects of adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Redox signalling in anchorage-dependent cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Measurement of the high-molecular weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

New perspectives into the molecular pathogenesis and treatment of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

PPARs and the complex journey to obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Cardioprotective effects of short-term caloric restriction are mediated by adiponectin via activation of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin promotes endothelial progenitor cell number and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Cyclooxygenase-2 induction by adiponectin is regulated by a sphingosine kinase-1 dependent mechanism in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Association between extent of thiazolidinedione exposure and risk of acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin suppresses proliferation and superoxide generation and enhances eNOS activity in endothelial cells treated with oxidized LDL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Anti-tumor necrosis factor therapy increases serum adiponectin levels with the improvement of endothelial dysfunction in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Plasma, urine, and renal expression of adiponectin in human systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin deficiency protects mice from chemically induced colonic inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin protects against angiotensin II or tumor necrosis factor alpha-induced endothelial cell monolayer hyperpermeability: role of cAMP/PKA signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adipocytokines: mediators linking adipose tissue, inflammation and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Insulin produces myogenesis in C2C12 myoblasts by induction of NF-kappaB and downregulation of AP-1 activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Adiponectin stimulates osteoblast differentiation through induction of COX2 in mesenchymal progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Circulating adiponectin and adiponectin receptor expression in skeletal muscle: effects of exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

The p38alpha/beta MAPK functions as a molecular switch to activate the quiescent satellite cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

LKB1 and AMPK in cell polarity and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Subcutaneous adipose tissue-derived stem cells facilitate colonic mucosal recovery from 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Entry of muscle satellite cells into the cell cycle requires sphingolipid signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Anoikis: a necessary death program for anchorage-dependent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903530712

10.1517/14728220903530712

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference