(Q37660998)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20027669%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

review article

1 reference

title

Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20027669%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20027669%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Martin Doležal

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20027669%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Martin Doležal

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20027669%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

4

Frank Gunn-Moore

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20027669%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

5

Kamil Kuca

1 reference

15 January 2020

publication date

21 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20027669%20AND%20SRC:MED&resulttype=core&format=json

Medicinal Research Reviews

15 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20027669%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

31

1 reference

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15 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20027669%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

548-575

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20027669%20AND%20SRC:MED&resulttype=core&format=json

Organophosphate poisoning

15 January 2020

cites work

1 reference

Organophosphates⧸Nerve Agent Poisoning: Mechanism of Action, Diagnosis, Prophylaxis, And Treatment

21 January 2018

1 reference

21 January 2018

1 reference

Lessons to be learnt from organophosphorus pesticide poisoning for the treatment of nerve agent poisoning

21 January 2018

1 reference

New potent reactivators of acetocholinesterase inhibited by tetraethyl pyrophosphate.

21 January 2018

1 reference

Oximes in acute organophosphorus pesticide poisoning: a systematic review of clinical trials

21 January 2018

1 reference

Suicide by intentional ingestion of pesticides: a continuing tragedy in developing countries

21 January 2018

1 reference

Where is the evidence for treatments used in pesticide poisoning? Is clinical toxicology fiddling while the developing world burns?

21 January 2018

1 reference

Management of acute organophosphorus pesticide poisoning

21 January 2018

1 reference

Reappraisal of indications and limitations of oxime therapy in organophosphate poisoning.

21 January 2018

1 reference

The inhibition of acetylcholinesterases by anionic organophosphorus compounds.

21 January 2018

1 reference

Reactivation kinetics of diethylphosphoryl acetylcholine esterase.

21 January 2018

1 reference

Avian embryonic brain reaggregate culture system. II. NTE activity discriminates between effects of a single neuropathic or nonneuropathic organophosphorus compound exposure.

21 January 2018

1 reference

Inhibition of acetylcholinesterase by (1S,3S)-isomalathion proceeds with loss of thiomethyl: kinetic and mass spectral evidence for an unexpected primary leaving group

21 January 2018

1 reference

Probing the active sites of butyrylcholinesterase and cholesterol esterase with isomalathion: conserved stereoselective inactivation of serine hydrolases structurally related to acetylcholinesterase.

21 January 2018

1 reference

Stereoselective inactivation of Torpedo californica acetylcholinesterase by isomalathion: inhibitory reactions with (1R)- and (1S)-isomers proceed by different mechanisms

21 January 2018

1 reference

The relationship between isofenphos cholinergic toxicity and the development of polyneuropathy in hens and humans

21 January 2018

1 reference

Permanent paralysis at sites of dermal exposure to chlorpyrifos

21 January 2018

1 reference

Combined effect of organophosphorus hydrolase and oxime on the reactivation rate of diethylphosphoryl-acetylcholinesterase conjugates.

21 January 2018

1 reference

Comparing therapeutic and prophylactic protection against the lethal effect of paraoxon

21 January 2018

1 reference

Enzyme reactivator treatment in organophosphate exposure: clinical relevance of thiocholinesteratic activity of pralidoxime

21 January 2018

1 reference

Effect of pyridostigmine, pralidoxime and their combination on survival and cholinesterase activity in rats exposed to the organophosphate paraoxon.

21 January 2018

1 reference

Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response

21 January 2018

1 reference

Acute stress facilitates long-lasting changes in cholinergic gene expression

21 January 2018

1 reference

Pralidoxime iodide (2-pAM) penetrates across the blood-brain barrier

21 January 2018

1 reference

Pralidoxime in carbaryl poisoning: an animal model.

21 January 2018

1 reference

Cholinesterase status, pharmacokinetics and laboratory findings during obidoxime therapy in organophosphate poisoned patients

21 January 2018

1 reference

Differential reactivation by HI-6 in vivo of paraoxon-inhibited rat brain acetylcholinesterase molecular forms

21 January 2018

1 reference

Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase

21 January 2018

1 reference

Comparison of oxime-initiated reactivation of organophosphorous-inhibited acetylcholinesterase in brains of avian embryos

21 January 2018

1 reference

Reactivation of immobilized acetyl cholinesterase in an amperometric biosensor for organophosphorus pesticide

21 January 2018

1 reference

Reactivation and aging kinetics of human acetylcholinesterase inhibited by organophosphonylcholines

21 January 2018

1 reference

Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes

21 January 2018

1 reference

Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro.

21 January 2018

1 reference

Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro

21 January 2018

1 reference

Unequal efficacy of pyridinium oximes in acute organophosphate poisoning

21 January 2018

1 reference

Structure-activity relationships for reactivators of organophosphorus-inhibited acetylcholinesterase: quaternary salts of 2-[(hydroxyimino)methyl]imidazole.

21 January 2018

1 reference

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 2. Preparation and in vitro and in vivo evaluation of 1-(alkoxymethyl)-2-[(hydroxyimino)methyl]-3-methylimida zolium halides for reactivation of organophosphorus-inhibited acetylcholinesterases.

21 January 2018

1 reference

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 3. Synthesis and evaluation of (alkenyloxy)-, (alkynyloxy)-, and (aralkyloxy)methyl quaternarized 2-[(hydroxyimino)methyl]-1-alkylimidazolium halides as reactivators and therapy for soman intoxi

21 January 2018

1 reference

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 4. Effect of various side-chain substituents on therapeutic activity against anticholinesterase intoxication

21 January 2018

1 reference

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 5. Structure-activity relationships for side-chain nitro-, sulfone-, amino-, and aminosulfonyl-substituted analogues for therapy against anticholinesterase intoxication

21 January 2018

1 reference

Sulfur derivatives of 2-oxopropanal oxime as reactivators of organophosphate-inhibited acetylcholinesterase in vitro: synthesis and structure-reactivity relationships

21 January 2018

1 reference

Rational design of alkylene-linked bis-pyridiniumaldoximes as improved acetylcholinesterase reactivators

21 January 2018

1 reference

Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

21 January 2018

1 reference

Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

21 January 2018

1 reference

In vitro oxime protection of human red blood cell acetylcholinesterase inhibited by diisopropyl-fluorophosphate

21 January 2018

1 reference

Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

21 January 2018

1 reference

Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

21 January 2018

1 reference

Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

21 January 2018

1 reference

Design of a potent reactivator of tabun-inhibited acetylcholinesterase--synthesis and evaluation of (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide (K203).

21 January 2018

1 reference

An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice

21 January 2018

1 reference

Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.

21 January 2018

1 reference

Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase

21 January 2018

1 reference

Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon

21 January 2018

1 reference

In vitro oxime reactivation of red blood cell acetylcholinesterase inhibited by methyl-paraoxon.

21 January 2018

1 reference

Five oximes (K-27, K-48, obidoxime, HI-6 and trimedoxime) in comparison with pralidoxime: survival in rats exposed to methyl-paraoxon.

21 January 2018

1 reference

Measurement of K-27, an oxime-type cholinesterase reactivator by high-performance liquid chromatography with electrochemical detection from different biological samples

21 January 2018

1 reference

Quaternary salts of 4,3' and 4,4' bis-pyridinium monooximes: synthesis and biological activity

21 January 2018

1 reference

Quaternary salts of 4,3' and 4,4' bis-pyridinium monooximes. Part 2: synthesis and biological activity

21 January 2018

1 reference

New oxime reactivators connected with CH2O(CH2)nOCH2 linker and their reactivation potency for organophosphorus agents-inhibited acetylcholinesterase.

21 January 2018

1 reference

Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes

21 January 2018

1 reference

Reactivation potency of fluorinated pyridinium oximes for acetylcholinesterases inhibited by paraoxon organophosphorus agent.

21 January 2018

1 reference

Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase

21 January 2018

1 reference

Blood-brain barrier penetration of novel pyridinealdoxime methiodide (PAM)-type oximes examined by brain microdialysis with LC-MS/MS.

21 January 2018

1 reference

Structural requirements of acetylcholinesterase reactivators.

21 January 2018

1 reference

Aromatic amino‐acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept®) to cholinesterases

21 January 2018

1 reference

Efficacy of eight experimental bispyridinium oximes against paraoxon-induced mortality: comparison with the conventional oximes pralidoxime and obidoxime.

21 January 2018

1 reference

A comparison of neuroprotective efficacy of newly developed oximes (K203, K206) and commonly used oximes (obidoxime, HI-6) in tabun-poisoned rats.

21 January 2018

1 reference

A comparison of the reactivating and therapeutic efficacy of newly developed bispyridinium oximes (K250, K251) with commonly used oximes against tabun in rats and mice.

21 January 2018

1 reference

New bispyridinium oximes: in vitro and in vivo evaluation of their biological efficiency in soman and tabun poisoning

21 January 2018

1 reference

Treatment of organophosphate intoxication using cholinesterase reactivators: facts and fiction.

21 January 2018

1 reference

Pesticide poisoning in south India: opportunities for prevention and improved medical management.

21 January 2018

1 reference

Selective and irreversible inhibitors of aphid acetylcholinesterases: steps toward human-safe insecticides

21 January 2018

1 reference

Selective and Irreversible Inhibitors of Mosquito Acetylcholinesterases for Controlling Malaria and Other Mosquito-Borne Diseases

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MED.20192

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20027669%20AND%20SRC:MED&resulttype=core&format=json

release_mth5iuyd2zaklg5utt47o7dtsq

15 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mth5iuyd2zaklg5utt47o7dtsq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference