(Q37679135)

English

Bacterial β-glucuronidase inhibition protects mice against enteropathy induced by indomethacin, ketoprofen or diclofenac: mode of action and pharmacokinetics

scientific article published on 05 July 2013

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scholarly article

1 reference

Europe PubMed Central

21 August 2017

Bacterial β-glucuronidase inhibition protects mice against enteropathy induced by indomethacin, ketoprofen or diclofenac: mode of action and pharmacokinetics (English)

1 reference

Europe PubMed Central

21 August 2017

1 reference

based on heuristic

inferred from title

(RS)-ketoprofen

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

Matthew R Redinbo

5

object named as

Matthew R Redinbo

1 reference

Europe PubMed Central

21 August 2017

object named as

Kyle S Saitta

1

1 reference

ORCID Public Data File 2021

author name string

Carmen Zhang

2

1 reference

Europe PubMed Central

21 August 2017

Kang Kwang Lee

3

1 reference

Europe PubMed Central

21 August 2017

Kazunori Fujimoto

4

1 reference

Europe PubMed Central

21 August 2017

Urs A Boelsterli

6

1 reference

Europe PubMed Central

21 August 2017

language of work or name

0 references

publication date

5 July 2013

1 reference

Europe PubMed Central

21 August 2017

1 reference

Europe PubMed Central

21 August 2017

44

1 reference

Europe PubMed Central

21 August 2017

1

1 reference

Europe PubMed Central

21 August 2017

28-35

1 reference

Europe PubMed Central

21 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3972617/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Multiple NSAID-induced hits injure the small intestine: underlying mechanisms and novel strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

23 August 2017

Role of intestinal cytochrome p450 enzymes in diclofenac-induced toxicity in the small intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

23 August 2017

Pharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

23 August 2017

Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

23 August 2017

Enantioselective pharmacodynamics and pharmacokinetics of chiral non-steroidal anti-inflammatory drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

23 August 2017

Ketoprofen (19.583 R.P.) (2-(3-benzoylphenyl)-propionic acid). Main pharmacological properties--outline of toxicological and pharmacokinetic data.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

23 August 2017

Gastrointestinal safety of NSAIDs and over-the-counter analgesics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

6 September 2017

NSAID gastropathy and enteropathy: distinct pathogenesis likely necessitates distinct prevention strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

6 September 2017

Nonsteroidal antiinflammatory drug-related injury to the gastrointestinal tract: clinical picture, pathogenesis, and prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

6 September 2017

Critical role of free cytosolic calcium, but not uncoupling, in mitochondrial permeability transition and cell death induced by diclofenac oxidative metabolites in immortalized human hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

14 September 2017

Diclofenac covalent protein binding is dependent on acyl glucuronide formation and is inversely related to P450-mediated acute cell injury in cultured rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

25 June 2018

Enterohepatic circulation of indomethacin and its role in intestinal irritation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

25 June 2018

Hemin ameliorates indomethacin-induced small intestinal injury in mice through the induction of heme oxygenase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

1 September 2018

Diclofenac metabolism in the mouse: novel in vivo metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

1 September 2018

Protection from diclofenac-induced small intestinal injury by the JNK inhibitor SP600125 in a mouse model of NSAID-associated enteropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

1 September 2018

The role of gut microbiota in drug response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

1 September 2018

Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

1 September 2018

Importance of biliary excretion of indomethacin in gastrointestinal and hepatic injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

1 September 2018

The use of the suicide CYP450 inhibitor ABT for distinguishing absorption and metabolism processes in in-vivo pharmacokinetic screens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

1 September 2018

Effective dosing regimen of 1-aminobenzotriazole for inhibition of antipyrine clearance in guinea pigs and mice using serial sampling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

1 September 2018

Assessing the dose-dependency of allometric scaling performance using physiologically based pharmacokinetic modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

1 September 2018

Pharmacokinetics of 5 (and 6)-carboxy-2',7'-dichlorofluorescein and its diacetate promoiety in the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972617

1 September 2018

Oxidation of a metabolite of indomethacin (Desmethyldeschlorobenzoylindomethacin) to reactive intermediates by activated neutrophils, hypochlorous acid, and the myeloperoxidase system

1 reference

https://pubmed.ncbi.nlm.nih.gov/23829165

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diclofenac acyl glucuronide, a major biliary metabolite, is directly involved in small intestinal injury in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23829165

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphodiesterase inhibitors prevent NSAID enteropathy independently of effects on TNF-alpha release

1 reference

https://pubmed.ncbi.nlm.nih.gov/23829165

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23829165

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of tumor necrosis factor-α in the pathogenesis of indomethacin-induced small intestinal injury in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23829165

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A high throughput in vitro mrp2 assay to predict in vivo biliary excretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23829165

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective protein adduct formation of diclofenac glucuronide is critically dependent on the rat canalicular conjugate export pump (Mrp2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23829165

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3109/00498254.2013.811314

1 reference

Europe PubMed Central

21 August 2017

1 reference

Europe PubMed Central

21 August 2017

1 reference

Europe PubMed Central

21 August 2017

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