(Q37681010)

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Induced pluripotent stem cells reveal functional differences between drugs currently investigated in patients with hutchinson-gilford progeria syndrome

scientific article published on 05 March 2014

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scholarly article

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Europe PubMed Central

21 August 2017

Induced pluripotent stem cells reveal functional differences between drugs currently investigated in patients with hutchinson-gilford progeria syndrome (English)

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Europe PubMed Central

21 August 2017

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Annachiara De Sandre-Giovannoli

10

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9 June 2020

Claire L Navarro

5

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9 June 2020

Cécile Martinat

7

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9 June 2020

11

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9 June 2020

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9 June 2020

Marc Peschanski

12

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Marc Peschanski

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9 June 2020

Anne-Laure Egesipe

3

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Anne-Laure Egesipe

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9 June 2020

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1

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Sophie Blondel

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9 June 2020

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Anne-Laure Jaskowiak

2

object named as

Anne-Laure Jaskowiak

1 reference

Europe PubMed Central

9 June 2020

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author name string

Amelie Le Corf

4

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9 June 2020

Véronique Cordette

6

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9 June 2020

Yacine Laabi

8

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9 June 2020

Karima Djabali

9

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9 June 2020

publication date

5 March 2014

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21 August 2017

Stem Cells Translational Medicine

1 reference

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9 June 2020

3

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9 June 2020

4

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9 June 2020

510-519

1 reference

Europe PubMed Central

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9 June 2020

Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome: implications for normal aging and age-dependent neurodegenerative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Effect of progerin on the accumulation of oxidized proteins in fibroblasts from Hutchinson Gilford progeria patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

1 reference

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23 August 2017

HGPS and related premature aging disorders: from genomic identification to the first therapeutic approaches

1 reference

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23 August 2017

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Phenotype and course of Hutchinson-Gilford progeria syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Molecular bases of progeroid syndromes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Lamin A-dependent nuclear defects in human aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Lamin a truncation in Hutchinson-Gilford progeria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

23 August 2017

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

1 reference

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23 August 2017

Combined mRNA and microRNA profiling reveals that miR-148a and miR-20b control human mesenchymal stem cell phenotype via EPAS1.

1 reference

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14 September 2017

Increased expression of the Hutchinson-Gilford progeria syndrome truncated lamin A transcript during cell aging

1 reference

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14 September 2017

A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects

1 reference

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25 June 2018

Energy metabolism in cultured human fibroblasts during aging in vitro

1 reference

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25 June 2018

[Human pluripotent stem cells: opening key for pathological modeling].

1 reference

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1 September 2018

Hutchinson-Gilford progeria syndrome: review of the phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

1 September 2018

Farnesyl and geranylgeranyl transferase inhibitors induce G1 arrest by targeting the proteasome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973719

1 September 2018

Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA

1 reference

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21 January 2018

Identifiers

10.5966/SCTM.2013-0168

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24598781%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24598781%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24598781%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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