(Q37682659)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

review article

1 reference

title

Microtubule targeting agents: from biophysics to proteomics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

Pascal Verdier-Pinard

2

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17 January 2020

Claude Villard

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Daniel Lafitte

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

D Calligaris

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

F Devred

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

D Braguer

5

1 reference

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17 January 2020

publication date

28 January 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

Cellular and Molecular Life Sciences

17 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

67

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

1089-1104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00018-009-0245-6

17 January 2020

exact match

0 references

cites work

Vinblastine suppresses dynamics of individual microtubules in living interphase cells

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-009-0245-6

Are tubulin isotypes functionally significant

21 January 2018

1 reference

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Altered beta-tubulin isotype expression in paclitaxel-resistant human prostate carcinoma cells

21 January 2018

1 reference

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Taxol and anti-stathmin therapy: a synergistic combination that targets the mitotic spindle

21 January 2018

1 reference

12 December 2020

1 reference

12 December 2020

Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline

1 reference

12 December 2020

The 4 A X-ray structure of a tubulin:stathmin-like domain complex

1 reference

12 December 2020

Synthesis of a photoaffinity analog of taxol as an approach to identify the taxol binding site on microtubules

1 reference

12 December 2020

Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel

1 reference

12 December 2020

Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes

1 reference

12 December 2020

Proteomic characterization of cytoskeletal and mitochondrial class III beta-tubulin

1 reference

12 December 2020

Laulimalide and isolaulimalide, new paclitaxel-like microtubule-stabilizing agents.

1 reference

12 December 2020

Stu2p binds tubulin and undergoes an open-to-closed conformational change

1 reference

12 December 2020

2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.

1 reference

12 December 2020

Phase changes at the end of a microtubule with a GTP cap.

1 reference

12 December 2020

Taxanes, microtubules and chemoresistant breast cancer.

1 reference

12 December 2020

Photoaffinity labeling of tubulin with (2-nitro-4-azidophenyl)deacetylcolchicine: direct evidence for two colchicine binding sites

1 reference

12 December 2020

Analytical strategies for the screening and evaluation of chemically reactive drug metabolites

1 reference

12 December 2020

The solid state, solution and tubulin-bound conformations of agents that promote microtubule stabilization

1 reference

12 December 2020

Direct photoaffinity labeling of tubulin with taxol

1 reference

12 December 2020

Sustained intracellular retention of dolastatin 10 causes its potent antimitotic activity.

1 reference

12 December 2020

Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells

1 reference

12 December 2020

Immunostructural evidence for the template mechanism of microtubule nucleation

1 reference

12 December 2020

Direct photoaffinity labeling of tubulin with colchicine

1 reference

12 December 2020

A photoaffinity derivative of colchicine: 6'-(4'-azido-2'-nitrophenylamino)hexanoyldeacetylcolchicine. Photolabeling and location of the colchicine-binding site on the alpha-subunit of tubulin

1 reference

12 December 2020

A bi-modal approach against cancer: magnetic alginate nanoparticles for combined chemotherapy and hyperthermia

1 reference

12 December 2020

Distances between the Paclitaxel, Colchicine, and Exchangeable GTP Binding Sites on Tubulin†

1 reference

12 December 2020

A unique mode of microtubule stabilization induced by peloruside A

1 reference

12 December 2020

Isotope dilution strategies for absolute quantitative proteomics

1 reference

12 December 2020

Promotion of fluorescence upon binding of colchicine to tubulin

1 reference

12 December 2020

Novel agents that target tublin and related elements

1 reference

12 December 2020

Novel formulations of taxanes: a review. Old wine in a new bottle?

1 reference

12 December 2020

The interaction of baccatin III with the taxol binding site of microtubules determined by a homogeneous assay with fluorescent taxoid

1 reference

12 December 2020

Chemistry and biology of curacin A.

1 reference

12 December 2020

MS/MS methodology to improve subcellular mapping of cholesterol using TOF-SIMS

1 reference

12 December 2020

Mitotic spindle assembly and chromosome segregation: refocusing on microtubule dynamics

1 reference

12 December 2020

Interaction of vinblastine with calf brain tubulin: multiple equilibria

1 reference

12 December 2020

Structural intermediates in microtubule assembly and disassembly: how and why?

1 reference

12 December 2020

Identification of gamma-tubulin, a new member of the tubulin superfamily encoded by mipA gene of Aspergillus nidulans.

1 reference

12 December 2020

Quantitative chemical proteomics for identifying candidate drug targets

1 reference

12 December 2020

Tubulin is an inherent component of mitochondrial membranes that interacts with the voltage-dependent anion channel

1 reference

12 December 2020

Taxotere resistance in SUIT Taxotere resistance in pancreatic carcinoma cell line SUIT 2 and its sublines.

1 reference

12 December 2020

Synthesis and biological evaluation of (-)-16-normethyldictyostatin: a potent analogue of (-)-dictyostatin

1 reference

12 December 2020

Dynamic instability of microtubules assembled from microtubule-associated protein-free tubulin: neither variability of growth and shortening rates nor "rescue" requires microtubule-associated proteins.

1 reference

12 December 2020

Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines

1 reference

12 December 2020

Comparative preclinical pharmacokinetic and metabolic studies of the combretastatin prodrugs combretastatin A4 phosphate and A1 phosphate

1 reference

12 December 2020

A subcelluar proteomic investigation into vincristine-resistant gastric cancer cell line

1 reference

12 December 2020

Substoichiometric binding of taxol suppresses microtubule dynamics.

1 reference

12 December 2020

Familial Mediterranean fever: clinical, molecular and management advancements

1 reference

12 December 2020

Rotational-echo double-resonance NMR distance measurements for the tubulin-bound Paclitaxel conformation

1 reference

12 December 2020

The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity.

1 reference

12 December 2020

The role of beta-tubulin isotypes in resistance to antimitotic drugs

1 reference

12 December 2020

Miniaturization and validation of a sensitive multiparametric cell-based assay for the concomitant detection of microtubule-destabilizing and microtubule-stabilizing agents

1 reference

12 December 2020

Taxol binds to polymerized tubulin in vitro

1 reference

12 December 2020

Insights into the mechanism of microtubule stabilization by Taxol.

1 reference

12 December 2020

Synergistic antiangiogenic effects of stathmin inhibition and taxol exposure.

1 reference

12 December 2020

Assembly dynamics of microtubules at molecular resolution

1 reference

12 December 2020

Characterization of the Taxol Binding Site on the Microtubule

1 reference

12 December 2020

Interactions of 2-methoxyestradiol, an endogenous mammalian metabolite, with unpolymerized tubulin and with tubulin polymers

1 reference

12 December 2020

A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin.

1 reference

12 December 2020

Effect of stathmin on the sensitivity to antimicrotubule drugs in human breast cancer.

1 reference

12 December 2020

Silencing of stathmin induces tumor-suppressor function in breast cancer cell lines harboring mutant p53.

1 reference

12 December 2020

Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly.

1 reference

12 December 2020

The development of the DIGE system: 2D fluorescence difference gel analysis technology

1 reference

12 December 2020

Development of a sensitive liquid chromatography method coupled with a tandem mass spectrometric detection for the clinical analysis of vinflunine and 4-O-deacetyl vinflunine in blood, urine and faeces

1 reference

12 December 2020

Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging

1 reference

12 December 2020

XMAP215 is a processive microtubule polymerase

1 reference

12 December 2020

Tubulin dimers oligomerize before their incorporation into microtubules

1 reference

12 December 2020

Stathmin and tubulin expression and survival of ovarian cancer patients receiving platinum treatment with and without paclitaxel.

1 reference

12 December 2020

Differential in vitro association of vinca alkaloid-induced tubulin spiral filaments into aggregated spirals

1 reference

12 December 2020

Photoaffinity labeling of tubulin subunits with a photoactive analogue of vinblastine

1 reference

12 December 2020

Colchicine for acute gout

1 reference

12 December 2020

DNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose

1 reference

12 December 2020

Structure of the alpha beta tubulin dimer by electron crystallography

1 reference

12 December 2020

High-spatial resolution mass spectrometric imaging of peptide and protein distributions on a surface

1 reference

12 December 2020

Tubulin proteomics: towards breaking the code.

1 reference

12 December 2020

Structural basis for the regulation of tubulin by vinblastine

1 reference

12 December 2020

Tag-mass: specific molecular imaging of transcriptome and proteome by mass spectrometry based on photocleavable tag.

1 reference

12 December 2020

Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway

1 reference

12 December 2020

Localization of the colchicine-binding site of tubulin

1 reference

12 December 2020

The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells

1 reference

12 December 2020

Stathmin/Op18 is a novel mediator of vinblastine activity

1 reference

12 December 2020

Structure of the gamma-tubulin ring complex: a template for microtubule nucleation

1 reference

12 December 2020

Microtubule nucleation.

1 reference

12 December 2020

Microtubule dynamics in vitro are regulated by the tubulin isotype composition

1 reference

12 December 2020

Microtubules: evidence for 13 protofilaments

1 reference

12 December 2020

Specific MALDI Imaging and Profiling for Biomarker Hunting and Validation: Fragment of the 11S Proteasome Activator Complex, Reg Alpha Fragment, Is a New Potential Ovary Cancer Biomarker

1 reference

12 December 2020

Microtubule-stabilizing agents based on designed laulimalide analogues

1 reference

12 December 2020

Biosynthesis of radiolabeled curacin A and its rapid and apparently irreversible binding to the colchicine site of tubulin.

1 reference

12 December 2020

Vinca alkaloid-induced tubulin spiral formation correlates with cytotoxicity in the leukemic L1210 cell line

1 reference

12 December 2020

Tumor targeting by conjugation of DHA to paclitaxel

1 reference

12 December 2020

Effect of colcemid on the locomotory behaviour of fibroblasts

1 reference

12 December 2020

Preclinical pharmacology of BMS-275183, an orally active taxane

1 reference

12 December 2020

Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin

1 reference

12 December 2020

Computational and molecular modeling evaluation of the structural basis for tubulin polymerization inhibition by colchicine site agents.

1 reference

12 December 2020

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

1 reference

12 December 2020

Ubiquitin-dependent proteolysis of the microtubule end-binding protein 1, EB1, is controlled by the COP9 signalosome: possible consequences for microtubule filament stability.

1 reference

12 December 2020

Ixabepilone: a novel antineoplastic agent with low susceptibility to multiple tumor resistance mechanisms

1 reference

12 December 2020

Relating molecular flexibility to function: a case study of tubulin

1 reference

12 December 2020

Anti-proliferative activity of a new class of taxanes (14β-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells

1 reference

12 December 2020

Localization of the vinblastine-binding site on beta-tubulin.

1 reference

12 December 2020

In vitro effect of cryptophycin 52 on microtubule assembly and tubulin: molecular modeling of the mechanism of action of a new antimitotic drug

1 reference

12 December 2020

Identification and characterization of an intermediate taxol binding site within microtubule nanopores and a mechanism for tubulin isotype binding selectivity.

1 reference

12 December 2020

Mass spectrometric-based approaches in quantitative proteomics

1 reference

12 December 2020

Antitumor activity of vinflunine: effector pathways and potential for synergies

1 reference

12 December 2020

Abilities of 3,4-diarylfuran-2-one analogs of combretastatin A-4 to inhibit both proliferation of tumor cell lines and growth of relevant tumors in nude mice.

1 reference

12 December 2020

Expression of a multidrug-resistance gene in human tumors and tissues

1 reference

12 December 2020

Direct Analysis of Tubulin Expression in Cancer Cell Lines by Electrospray Ionization Mass Spectrometry

1 reference

12 December 2020

Metamorphic enzyme assembly in polyketide diversification

1 reference

12 December 2020

Microtubule dynamics in living cells

1 reference

12 December 2020

Refined structure of alpha beta-tubulin at 3.5 A resolution

1 reference

12 December 2020

Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity

1 reference

12 December 2020

Structural insight into the inhibition of tubulin by vinca domain peptide ligands

1 reference

12 December 2020

Chloroacetates of 2- and 3-demethylthiocolchicine: specific covalent interactions with tubulin with preferential labeling of the beta-subunit

1 reference

12 December 2020

An abundance of tubulins

1 reference

12 December 2020

Nucleotide dependence and cytoplasmic localization of a 49-kDa microtubule cross-linking protein from the brine shrimp, Artemia.

1 reference

12 December 2020

Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation.

1 reference

12 December 2020

Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin.

1 reference

12 December 2020

The tubulin fraternity: alpha to eta

1 reference

12 December 2020

Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.

1 reference

12 December 2020

Isobaric tags for relative and absolute quantitation (iTRAQ) reproducibility: Implication of multiple injections

1 reference

12 December 2020

Post-translational modifications regulate microtubule function

1 reference

12 December 2020

Overcoming tumor drug resistance with high-affinity taxanes: a SAR study of C2-modified 7-acyl-10-deacetyl cephalomannines.

1 reference

12 December 2020

Thermodynamics of ligand-induced assembly of tubulin.

1 reference

12 December 2020

Effects of stathmin inhibition on the mitotic spindle.

1 reference

12 December 2020

Resistance to microtubule-targeted cytotoxins in a K562 leukemia cell variant associated with altered tubulin expression and polymerization.

1 reference

12 December 2020

Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data

1 reference

12 December 2020

Modulation of microtubule dynamics by drugs: a paradigm for the actions of cellular regulators

1 reference

12 December 2020

Matrix-assisted laser desorption/ionization-ion mobility separation-mass spectrometry imaging of vinblastine in whole body tissue sections

1 reference

12 December 2020

Mutations in beta-tubulin map to domains involved in regulation of microtubule stability in epothilone-resistant cell lines.

1 reference

12 December 2020

The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography

1 reference

12 December 2020

Antiangiogenic concentrations of vinflunine increase the interphase microtubule dynamics and decrease the motility of endothelial cells.

1 reference

12 December 2020

The extended tubulin superfamily

1 reference

12 December 2020

Reversal of stathmin-mediated resistance to paclitaxel and vinblastine in human breast carcinoma cells

1 reference

12 December 2020

Caulerpenyne binding to tubulin: structural modifications by a non conventional pharmacological agent

1 reference

12 December 2020

Estramustine depolymerizes microtubules by binding to tubulin

1 reference

12 December 2020

Specific affinity labelling of tubulin with bromocolchicine

1 reference

12 December 2020

Mechanisms of taxotere-related drug resistance in pancreatic carcinoma

1 reference

12 December 2020

Label-free protein quantification using LC-coupled ion trap or FT mass spectrometry: Reproducibility, linearity, and application with complex proteomes

1 reference

12 December 2020

Vinflunine, a novel microtubule inhibitor, suppresses calmodulin interaction with the microtubule-associated protein STOP.

1 reference

12 December 2020

Structure and thermodynamics of the tubulin-stathmin interaction

1 reference

12 December 2020

The spindle: a dynamic assembly of microtubules and motors

1 reference

12 December 2020

Peloruside A does not bind to the taxoid site on beta-tubulin and retains its activity in multidrug-resistant cell lines

1 reference

12 December 2020

Vinflunine, a second generation novel Vinca Alkaloid with a distinctive pharmacological profile, now in clinical development and prospects for future mitotic blockers

1 reference

12 December 2020

Markers predicting clinical benefit in breast cancer from microtubule-targeting agents

1 reference

12 December 2020

Are Cytoplasmic Microtubules Heteropolymers?

1 reference

12 December 2020

10.1007/S00018-009-0245-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference