(Q37682680)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107928%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

review article

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title

Targeting glial cells to elucidate the pathogenesis of Huntington's disease (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107928%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107928%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Han-Yun Hsiao

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107928%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

publication date

28 January 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107928%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

published in

Molecular Neurobiology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107928%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107928%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

2-3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107928%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

248-255

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107928%20AND%20SRC:MED&resulttype=core&format=json

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

17 January 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12035-009-8097-5

Combination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12035-009-8097-5

Ethanol intake enhances inflammatory mediators in brain: role of glial cells and TLR4/IL-1RI receptors

21 January 2018

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12 December 2020

Therapeutic interventions for disease progression in Huntington's disease

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12 December 2020

Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases

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12 December 2020

Histone deacetylase inhibition modulates kynurenine pathway activation in yeast, microglia, and mice expressing a mutant huntingtin fragment.

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12 December 2020

Widespread expression of Huntington's disease gene (IT15) protein product

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12 December 2020

Astroglia in dementia and Alzheimer's disease.

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12 December 2020

Reactive astrocytes: cellular and molecular cues to biological function

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12 December 2020

Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice

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12 December 2020

Mice transgenic for the human Huntington's disease mutation have reduced sensitivity to kainic acid toxicity

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12 December 2020

NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

1 reference

12 December 2020

Mitochondrial involvement in Parkinson's disease

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12 December 2020

Immunotherapeutic Approaches to Alzheimer's Disease

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12 December 2020

Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder?

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12 December 2020

Impaired glutamate uptake in the R6 Huntington's disease transgenic mice.

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12 December 2020

Chemokines and chemokine receptors in the CNS: a possible role in neuroinflammation and patterning

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12 December 2020

Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse.

1 reference

12 December 2020

Glucocorticoid receptor-nitric oxide crosstalk and vulnerability to experimental parkinsonism: pivotal role for glia-neuron interactions

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12 December 2020

Opposite effects of the A2A receptor agonist CGS21680 in the striatum of Huntington's disease versus wild-type mice.

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12 December 2020

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

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12 December 2020

Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice

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12 December 2020

Inflammation of the brain in Alzheimer's disease: implications for therapy.

1 reference

12 December 2020

Astrocytes, from brain glue to communication elements: the revolution continues

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12 December 2020

Neuroprotective role of the innate immune system by microglia

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12 December 2020

Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention.

1 reference

12 December 2020

Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms

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12 December 2020

beta-Amyloid protein-dependent nitric oxide production from microglial cells and neurotoxicity

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12 December 2020

Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease

1 reference

12 December 2020

Microglia and Macrophage Activation and the Regulation of Complement-Receptor-3 (CR3/MAC-1)-Mediated Myelin Phagocytosis in Injury and Disease

1 reference

12 December 2020

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

12 December 2020

Inflammation, anti-inflammatory agents and Alzheimer disease: the last 12 years

1 reference

12 December 2020

Neurological abnormalities in a knock-in mouse model of Huntington's disease

1 reference

12 December 2020

Nitric oxide and nitric oxide synthase in Huntington's disease

1 reference

12 December 2020

Triptolide inhibits amyloid-beta1-42-induced TNF-alpha and IL-1beta production in cultured rat microglia

1 reference

12 December 2020

Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice

1 reference

12 December 2020

Glial reactions in Parkinson's disease

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12 December 2020

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

1 reference

12 December 2020

Therapeutic approaches to inflammation in neurodegenerative disease

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12 December 2020

Minocycline affects microglia activation, Abeta deposition, and behavior in APP-tg mice

1 reference

12 December 2020

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

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12 December 2020

Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice

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12 December 2020

Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease

1 reference

12 December 2020

Inflammation in Parkinson's disease.

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12 December 2020

Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis

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12 December 2020

RANTES promotes growth and survival of human first-trimester forebrain astrocytes

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12 December 2020

Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2.

1 reference

12 December 2020

Mechanisms of microglia accumulation in Alzheimer's disease: therapeutic implications

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12 December 2020

ALS: a disease of motor neurons and their nonneuronal neighbors

1 reference

12 December 2020

Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease

1 reference

12 December 2020

Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

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12 December 2020

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

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12 December 2020

Glial neuronal signaling in the central nervous system

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12 December 2020

The therapeutic role of creatine in Huntington's disease

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12 December 2020

Force-plate quantification of progressive behavioral deficits in the R6/2 mouse model of Huntington's disease

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12 December 2020

Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

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12 December 2020

Neurodegenerative disorders: George Huntington's description of hereditary chorea

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12 December 2020

The corticostriatal pathway in Huntington's disease

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12 December 2020

Huntingtin-protein interactions and the pathogenesis of Huntington's disease

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12 December 2020

Transgenic mouse model of tau pathology in astrocytes leading to nervous system degeneration.

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12 December 2020

Acetylation targets mutant huntingtin to autophagosomes for degradation

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12 December 2020

Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes.

1 reference

12 December 2020

Glutamate transporter gene expression in amyotrophic lateral sclerosis motor cortex

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12 December 2020

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

12 December 2020

Selective injury to dopaminergic neurons up-regulates GDNF in substantia nigra postnatal cell cultures: role of neuron-glia crosstalk

1 reference

12 December 2020

Inflammation in neurodegenerative disease--a double-edged sword

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12 December 2020

Mechanisms of Disease: astrocytes in neurodegenerative disease

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12 December 2020

RANTES: a versatile and controversial chemokine

1 reference

12 December 2020

Inflammation and Alzheimer's disease

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12 December 2020

Lack of minocycline efficiency in genetic models of Huntington's disease

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12 December 2020

Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

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12 December 2020

Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes

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12 December 2020

Innate immunity: the missing link in neuroprotection and neurodegeneration?

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12 December 2020

Glutamate transporters: animal models to neurologic disease

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12 December 2020

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

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12 December 2020

Transcriptional abnormalities in Huntington disease

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12 December 2020

Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.

1 reference

12 December 2020

Recent advances in understanding the pathogenesis of Huntington's disease

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12 December 2020

CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.

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12 December 2020

Oxidative stress and inflammation in Parkinson's disease: is there a causal link?

1 reference

12 December 2020

Microglia in cerebral ischemia: molecular actions and interactions

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12 December 2020

Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes.

1 reference

12 December 2020

Neurodegeneration or neuroprotection: the pivotal role of astrocytes

1 reference

12 December 2020

A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis

1 reference

12 December 2020

Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

1 reference

12 December 2020

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

1 reference

12 December 2020

The role of glial cells in Parkinson's disease

1 reference

12 December 2020

Inflammation and apoptosis: linked therapeutic targets in spinal cord injury

1 reference

12 December 2020

cAMP-response element-binding protein contributes to suppression of the A2A adenosine receptor promoter by mutant Huntingtin with expanded polyglutamine residues

1 reference

12 December 2020

Regulatory role of cytosolic phospholipase A2alpha in NADPH oxidase activity and in inducible nitric oxide synthase induction by aggregated Abeta1-42 in microglia.

1 reference

12 December 2020

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

1 reference

12 December 2020

Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways.

1 reference

12 December 2020

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

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12 December 2020

Oxidative damage in Huntington's disease

1 reference

12 December 2020

Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.

1 reference

12 December 2020

Dopamine but not 3,4-dihydroxy phenylacetic acid (DOPAC) inhibits brain respiratory chain activity by autoxidation and mitochondria catalyzed oxidation to quinone products: implications in Parkinson's disease

1 reference

12 December 2020

Microglial activation in presymptomatic Huntington's disease gene carriers

1 reference

12 December 2020

Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin

1 reference

12 December 2020

Neuronal nuclear membrane indentation and astrocyte/neuron ratio in Huntington's disease. A quantitative electron microscopic study

1 reference

12 December 2020

Therapeutic interventions for symptomatic treatment in Huntington's disease

1 reference

12 December 2020

The A2A adenosine receptor rescues the urea cycle deficiency of Huntington's disease by enhancing the activity of the ubiquitin-proteasome system

1 reference

12 December 2020

Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease

1 reference

12 December 2020

Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration

1 reference

12 December 2020

Microglial activation correlates with severity in Huntington disease: a clinical and PET study.

1 reference

12 December 2020

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

1 reference

12 December 2020

Striatal potassium channel dysfunction in Huntington's disease transgenic mice

1 reference

12 December 2020

Primary sensory neurons migrate in response to the chemokine RANTES

1 reference

12 December 2020

Aberrant amplification of A(2A) receptor signaling in striatal cells expressing mutant huntingtin

1 reference

12 December 2020

10.1007/S12035-009-8097-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107928%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference