(Q45305307)

11 December 2017

Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease (English)

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11 December 2017

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6

Gary Lynch

1 reference

11 December 2017

Danielle A Simmons

1

1 reference

11 December 2017

Malcolm Casale

2

1 reference

11 December 2017

Betzi Alcon

3

1 reference

11 December 2017

Nha Pham

4

1 reference

11 December 2017

Natasha Narayan

5

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11 December 2017

1 August 2007

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11 December 2017

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11 December 2017

55

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11 December 2017

1074-1084

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11 December 2017

10

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Early and progressive accumulation of reactive microglia in the Huntington disease brain

11 December 2017

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

MR evaluation of age-related increase of brain iron in young adult and older normal males

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Increased basal ganglia iron levels in Huntington disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Brain ferritin iron may influence age- and gender-related risks of neurodegeneration.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Brain ferritin iron as a risk factor for age at onset in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Mitochondrial dysfunction in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron status and neural functioning

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Brain iron pathways and their relevance to Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Role of iron in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Serum ferritin deficiency in Huntington's disease patients

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidative stress in Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Normal huntingtin function: an alternative approach to Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron regulation in the brain: histochemical, biochemical, and molecular considerations

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

A histochemical study of iron, transferrin, and ferritin in Alzheimer's diseased brains.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Isoforms of ferritin have a specific cellular distribution in the brain.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Amyloid-beta metal interaction and metal chelation.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Damage to the DNA bases in mammalian chromatin by hydrogen peroxide in the presence of ferric and cupric ions

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

In vitro studies of ferritin iron release and neurotoxicity.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Relative resistance of striatal neurons containing calbindin or parvalbumin to quinolinic acid-mediated excitotoxicity compared to other striatal neuron types.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Huntingtin inclusion bodies are iron-dependent centers of oxidative events.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Regional distribution of iron, transferrin, ferritin, and oxidatively-modified proteins in young and aged Fischer 344 rat brains.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Ferritin is a component of the neuritic (senile) plaque in Alzheimer dementia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidative stress and inflammation in Parkinson's disease: is there a causal link?

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

G proteins and small GTPases: distant relatives keep in touch.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Expression of ferritin protein and subunit mRNAs in normal and iron deficient rat brain.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Pathological relationships between microglial cell activity and tau and amyloid beta protein in patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Ascorbic acid and iron metabolism: alterations in lysosomal function

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Genetic contributions to Parkinson's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Ionized calcium-binding adapter molecule 1 immunoreactive cells change in the gerbil hippocampal CA1 region after ischemia/reperfusion.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Microglia-specific localisation of a novel calcium binding protein, Iba1

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Brain iron and ferritin in Parkinson's and Alzheimer's diseases.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidative stress in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Macrophage/microglia-specific protein Iba1 enhances membrane ruffling and Rac activation via phospholipase C-gamma -dependent pathway

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Ferritin immunohistochemistry as a marker for microglia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Does cellular iron dysregulation play a causative role in Parkinson's disease?

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Microglia in health and disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

The roles of iron in health and disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Theta stimulation polymerizes actin in dendritic spines of hippocampus.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Microglia density decreases with age in a mouse model of Huntington's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Cellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidation-induced ferritin turnover in microglial cells: role of proteasome.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Serum iron, total iron binding capacity and ferritin in early Huntington disease patients

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Decreased neuronal and increased oligodendroglial densities in Huntington's disease caudate nucleus

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Control of glial immune function by neurons

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron, neuroinflammation, and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Microglial activation correlates with severity in Huntington disease: a clinical and PET study.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

The specific vulnerability of the substantia nigra to MPTP is related to the presence of transition metals

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Overactivation of LPS-stimulated microglial cells by co-cultured neurons or neuron-conditioned medium.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Cellular iron metabolism.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Widespread expression of Huntington's disease gene (IT15) protein product

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Temporal variation of hydroxyl radical generation and 8-hydroxy-2'-deoxyguanosine formation by coarse and fine particulate matter

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Dystrophic microglia in the aging human brain.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Microglial senescence: does the brain's immune system have an expiration date?

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Reactive microgliosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron uptake by glial cells.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Imaging microglial activation in Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

The ubiquitin-proteasome system in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Neuropathological classification of Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Activated microglia cause superoxide-mediated release of iron from ferritin

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Activated microglia cause iron-dependent lipid peroxidation in the presence of ferritin.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Depletion of wild-type huntingtin in mouse models of neurologic diseases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Identifiers

DOI

10.1002/GLIA.20526

1 reference

11 December 2017

1 reference