(Q40206245)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

title

Huntingtin inclusion bodies are iron-dependent centers of oxidative events (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

4

1 reference

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22 December 2019

author name string

Wance J J Firdaus

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Andreas Wyttenbach

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Paola Giuliano

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

R William Currie

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

André-Patrick Arrigo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

language of work or name

English

0 references

publication date

1 December 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

volume

273

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

page(s)

5428-5441

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17116244%20AND%20SRC:MED&resulttype=core&format=json

Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat

22 December 2019

cites work

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Glutamine repeats and neurodegenerative diseases: molecular aspects

21 January 2018

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Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles

21 January 2018

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Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

21 January 2018

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

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Recent advances on the pathogenesis of Huntington's disease

21 January 2018

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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

21 January 2018

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Huntingtin aggregation and toxicity in Huntington's disease

21 January 2018

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Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

21 January 2018

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Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

21 January 2018

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Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

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Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease

21 January 2018

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Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila

21 January 2018

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

21 January 2018

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Aggresomes, inclusion bodies and protein aggregation

21 January 2018

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

21 January 2018

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Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

21 January 2018

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Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity

21 January 2018

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Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

21 January 2018

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Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease

21 January 2018

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Protein misfolding, amyloid formation, and neurodegeneration: a critical role for molecular chaperones?

21 January 2018

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Small stress protein Hsp27 accumulation during dopamine-mediated differentiation of rat olfactory neurons counteracts apoptosis

21 January 2018

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Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector

21 January 2018

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Impaired clearance of oxidised proteins in neurodegenerative diseases

21 January 2018

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21 January 2018

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Free radicals as mediators of neuronal injury.

21 January 2018

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Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease

21 January 2018

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Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment

21 January 2018

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Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse.

21 January 2018

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DNA damage induced by polyglutamine-expanded proteins

21 January 2018

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Analysis of oxidative events induced by expanded polyglutamine huntingtin exon 1 that are differentially restored by expression of heat shock proteins or treatment with an antioxidant.

21 January 2018

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Mechanisms for neuronal cell death and dysfunction in Huntington's disease: pathological cross-talk between the nucleus and the mitochondria?

21 January 2018

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In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease.

21 January 2018

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Superoxide anion generation by the cytochrome bc1 complex

21 January 2018

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Proteasome inhibitors induce intracellular protein aggregation and cell death by an oxygen-dependent mechanism.

21 January 2018

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alpha-Synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro.

21 January 2018

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Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease

21 January 2018

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Mitochondrial dysfunction in neurodegenerative diseases

21 January 2018

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Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment.

21 January 2018

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Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

21 January 2018

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Mammalian small stress proteins protect against oxidative stress through their ability to increase glucose-6-phosphate dehydrogenase activity and by maintaining optimal cellular detoxifying machinery

21 January 2018

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Hsp27: novel regulator of intracellular redox state

21 January 2018

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Hsp27 consolidates intracellular redox homeostasis by upholding glutathione in its reduced form and by decreasing iron intracellular levels.

21 January 2018

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Chemistry and biochemistry of oxidative stress in neurodegenerative disease

21 January 2018

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Metal-catalyzed disruption of membrane protein and lipid signaling in the pathogenesis of neurodegenerative disorders

21 January 2018

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New evidence that the Alzheimer beta-amyloid peptide does not spontaneously form free radicals: an ESR study using a series of spin-traps.

21 January 2018

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Inefficient degradation of truncated polyglutamine proteins by the proteasome

21 January 2018

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Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins

21 January 2018

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Carbonyl assays for determination of oxidatively modified proteins.

21 January 2018

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