(Q37690579)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

review article

1 reference

title

Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Spiros Linardopoulos

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

J Blagg

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

A D J Pearson

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

11 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

671-678

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/leu.2010.15

18 January 2020

exact match

0 references

cites work

The cellular geography of aurora kinases

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Validating Aurora B as an anti-cancer drug target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Aurora kinase inhibitors: identification and preclinical validation of their biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

The chromosomal passenger complex: guiding Aurora-B through mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Aurora kinases as anticancer drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Aurora-A kinase: a novel target of cellular immunotherapy for leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Aurora kinase inhibitory VX-680 increases Bax/Bcl-2 ratio and induces apoptosis in Aurora-A-high acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Aurora kinases: new targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Flying under the radar: the new wave of BCR-ABL inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Epidemiologic study on survival of chronic myeloid leukemia and Ph(+) acute lymphoblastic leukemia patients with BCR-ABL T315I mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

CrkL functions as a nuclear adaptor and transcriptional activator in Bcr-Abl-expressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Crystal structure of the T315I Abl mutant in complex with the aurora kinases inhibitor PHA-739358

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Cotreatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Preclinical characterization of Aurora kinase inhibitor R763/AS703569 identified through an image-based phenotypic screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

KW-2449, a novel multikinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

FLT3 mutations in acute myeloid leukemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

A pharmacodynamic study of the FLT3 inhibitor KW-2449 yields insight into the basis for clinical response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

A phase I dose-escalation study of danusertib (PHA-739358) administered as a 24-hour infusion with and without granulocyte colony-stimulating factor in a 14-day cycle in patients with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Strategies to reduce the risk of drug-induced QT interval prolongation: a pharmaceutical company perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

AZD1152 rapidly and negatively affects the growth and survival of human acute myeloid leukemia cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

Contribution of ABL kinase domain mutations to imatinib resistance in different subsets of Philadelphia-positive patients: by the GIMEMA Working Party on Chronic Myeloid Leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

MK-0457, a novel kinase inhibitor, is active in patients with chronic myeloid leukemia or acute lymphocytic leukemia with the T315I BCR-ABL mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

inferred from DOI database lookup

7 January 2021

based on heuristic

Therapeutic potential of JAK2 inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.15

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2010.15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20147976%20AND%20SRC:MED&resulttype=core&format=json

release_un55fdwltfgvbgsacgcixlcar4

18 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/un55fdwltfgvbgsacgcixlcar4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference