Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q37702155)
Watch
English
The controversial relationship between NLRP3, alum, danger signals and the next-generation adjuvants.
scientific article published on March 2010
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
The controversial relationship between NLRP3, alum, danger signals and the next-generation adjuvants
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
author
Roberto Spreafico
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
Alessandra Mortellaro
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
Paola Ricciardi-Castagnoli
series ordinal
2
object named as
Paola Ricciardi-Castagnoli
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
language of work or name
English
0 references
publication date
1 March 2010
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
published in
European Journal of Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
volume
40
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
page(s)
638-642
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
cites work
Approaching the asymptote? Evolution and revolution in immunology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
21 January 2018
Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
21 January 2018
Mechanism of action of clinically approved adjuvants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Imject Alum is not aluminum hydroxide adjuvant or aluminum phosphate adjuvant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular identification of a danger signal that alerts the immune system to dying cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the role of vaccine adjuvants in modulating dendritic cell activation and antigen presentation in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
(How) do aluminium adjuvants work?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of dendritic cells and induction of CD4(+) T cell differentiation by aluminum-containing adjuvants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of aluminum-containing adjuvants in antigen internalization by dendritic cells in vitro.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inflammasomes: guardians of the body
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gout-associated uric acid crystals activate the NALP3 inflammasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active caspase-1 is a regulator of unconventional protein secretion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aluminium adjuvants--in retrospect and prospect
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptors control activation of adaptive immune responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunological and inflammatory functions of the interleukin-1 family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PEG-uricase in the management of treatment-resistant gout and hyperuricemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extracellular signal-regulated kinase 1/extracellular signal-regulated kinase 2 mitogen-activated protein kinase signaling and activation of activator protein 1 and nuclear factor kappaB transcription factors play central roles in interleukin-8 expr
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The low-toxicity versions of LPS, MPL adjuvant and RC529, are efficient adjuvants for CD4+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adjuvants--a balance between toxicity and adjuvanticity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vaccine adjuvant systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The danger model: a renewed sense of self
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200940039
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/EJI.200940039
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
PubMed ID
20201020
1 reference
stated in
Europe PubMed Central
PubMed ID
20201020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20201020%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
ResearchGate publication ID
41722828
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit