(Q37706202)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis (English)

1 reference

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12 March 2020

3

1 reference

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12 March 2020

Osamu Ohara

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Toshinori Nakayama

11

1 reference

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12 March 2020

author name string

Makoto Kuwahara

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Junpei Suzuki

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Takeshi Yamada

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Makoto Kanoh

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Akira Matsumoto

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Saho Maruyama

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Kohei Kometani

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Tomohiro Kurosaki

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Masakatsu Yamashita

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

language of work or name

English

0 references

publication date

2 April 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

published in

Nature Communications

1 reference

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12 March 2020

volume

5

1 reference

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12 March 2020

page(s)

3555

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

12 March 2020

copyright license

start time

2 April 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms4555

0 references

cites work

A genome-wide regulatory network identifies key transcription factors for memory CD8⁺ T-cell development.

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Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells

23 August 2017

1 reference

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Bach2 maintains T cells in a naive state by suppressing effector memory-related genes

23 August 2017

1 reference

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BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis.

23 August 2017

1 reference

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Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

23 August 2017

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Roles and mechanisms of cellular senescence in regulation of tissue homeostasis

23 August 2017

1 reference

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Chronic inflammation and aging: DNA damage tips the balance

23 August 2017

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Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes

23 August 2017

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Trithorax group proteins: switching genes on and keeping them active

23 August 2017

1 reference

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Menin represses tumorigenesis via repressing cell proliferation

23 August 2017

1 reference

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Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

23 August 2017

1 reference

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Four faces of cellular senescence.

23 August 2017

1 reference

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The essence of senescence

23 August 2017

1 reference

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STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells

23 August 2017

1 reference

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Rheumatoid arthritis: a role for immunosenescence?

23 August 2017

1 reference

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Inflammatory networks during cellular senescence: causes and consequences

23 August 2017

1 reference

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Menin dynamics and functional insight: take your partners

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Senescent cells as a source of inflammatory factors for tumor progression

23 August 2017

1 reference

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Stress-activated cap'n'collar transcription factors in aging and human disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Multiple common variants for celiac disease influencing immune gene expression

23 August 2017

1 reference

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Granzymes in age-related cardiovascular and pulmonary diseases

23 August 2017

1 reference

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c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis

23 August 2017

1 reference

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Healing and hurting: molecular mechanisms, functions, and pathologies of cellular senescence

23 August 2017

1 reference

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PD-1+ memory phenotype CD4+ T cells expressing C/EBPalpha underlie T cell immunodepression in senescence and leukemia

23 August 2017

1 reference

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Suppression of lung adenocarcinoma through menin and polycomb gene-mediated repression of growth factor pleiotrophin

23 August 2017

1 reference

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T-cell immunosenescence: lessons learned from mouse models of aging

23 August 2017

1 reference

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Menin regulates the function of hematopoietic stem cells and lymphoid progenitors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

23 August 2017

1 reference

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Menin critically links MLL proteins with LEDGF on cancer-associated target genes

23 August 2017

1 reference

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Motif module map reveals enforcement of aging by continual NF-kappaB activity

23 August 2017

1 reference

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The expansion and maintenance of antigen-selected CD8(+) T cell clones

23 August 2017

1 reference

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The common biology of cancer and ageing

23 August 2017

1 reference

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Menin and its interacting proteins: elucidation of menin function

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis

23 August 2017

1 reference

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The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression

23 August 2017

1 reference

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Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

The transcriptional programme of antibody class switching involves the repressor Bach2.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Guidelines for diagnosis and therapy of MEN type 1 and type 2.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Inflamm-aging. An evolutionary perspective on immunosenescence

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Tumor suppressor menin: the essential role of nuclear localization signal domains in coordinating gene expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Molecular mechanisms involved in the aging of the T-cell immune response.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

NF-κB inhibition delays DNA damage-induced senescence and aging in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3988815

1 September 2018

Identifiers

DOI

10.1038/NCOMMS4555

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24694524%20AND%20SRC:MED&resulttype=core&format=json