(Q36911187)

17 August 2017

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title

The common biology of cancer and ageing (English)

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17 August 2017

Manuel Serrano

2

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Maria A Blasco

object named as

Maria A Blasco

series ordinal

3

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author name string

Toren Finkel

series ordinal

1

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PubMed ID

17700693

17 August 2017

language of work or name

English

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publication date

1 August 2007

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17 August 2017

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17 August 2017

448

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17 August 2017

767-774

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17 August 2017

7155

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https://scigraph.springernature.com/pub.10.1038/nature05985

17 August 2017

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Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.

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Constitutive telomerase expression promotes mammary carcinomas in aging mice

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Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice.

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Conditional telomerase induction causes proliferation of hair follicle stem cells

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Specific association of human telomerase activity with immortal cells and cancer

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7 January 2021

Telomerase activity in human ovarian carcinoma

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7 January 2021

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

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7 January 2021

Loss of autophagy in the central nervous system causes neurodegeneration in mice

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7 January 2021

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

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7 January 2021

Autophagy genes are essential for dauer development and life-span extension in C. elegans

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7 January 2021

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

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7 January 2021

p53 regulates mitochondrial respiration

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7 January 2021

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Genetics: influence of TOR kinase on lifespan in C. elegans

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Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

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7 January 2021

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

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7 January 2021

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

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7 January 2021

The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.

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7 January 2021

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

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7 January 2021

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

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https://api.crossref.org/works/10.1038%2FNATURE05985

7 January 2021

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

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https://api.crossref.org/works/10.1038%2FNATURE05985

7 January 2021

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

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https://api.crossref.org/works/10.1038%2FNATURE05985

7 January 2021

Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

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https://api.crossref.org/works/10.1038%2FNATURE05985

7 January 2021

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes.

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https://api.crossref.org/works/10.1038%2FNATURE05985

7 January 2021

Hypersensitivity to oxygen and shortened lifespan in a Drosophila mitochondrial complex II mutant

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https://api.crossref.org/works/10.1038%2FNATURE05985

7 January 2021

Rates of behavior and aging specified by mitochondrial function during development

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https://api.crossref.org/works/10.1038%2FNATURE05985

7 January 2021

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

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https://api.crossref.org/works/10.1038%2FNATURE05985

7 January 2021

Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways

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https://api.crossref.org/works/10.1038%2FNATURE05985

7 January 2021

Identifiers

DOI

10.1038/NATURE05985

1 reference

17 August 2017

1 reference

PubMed ID

17700693