(Q37712545)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Tommy Tillman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Mary H Cheng

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Qiang Chen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Pei Tang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

1 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

number of pages

8

1 reference

based on heuristic

inferred from page(s)

published in

Biochemical Journal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

449

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

61-68

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

All-atom empirical potential for molecular modeling and dynamics studies of proteins

13 February 2020

cites work

1 reference

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23 August 2017

1 reference

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Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals

23 August 2017

1 reference

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Charge and geometry of residues in the loop 2 β hairpin differentially affect agonist and ethanol sensitivity in glycine receptors

23 August 2017

1 reference

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Isoflurane alters the structure and dynamics of GLIC.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family

23 August 2017

1 reference

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Principles of activation and permeation in an anion-selective Cys-loop receptor

23 August 2017

1 reference

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Microsecond simulations indicate that ethanol binds between subunits and could stabilize an open-state model of a glycine receptor

23 August 2017

1 reference

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Linking of Glycine Receptor Transmembrane Segments Three and Four Allows Assignment of Intrasubunit-Facing Residues

23 August 2017

1 reference

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X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

23 August 2017

1 reference

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Ion selectivity mechanism in a bacterial pentameric ligand-gated ion channel

23 August 2017

1 reference

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Modeling anesthetic binding sites within the glycine alpha one receptor based on prokaryotic ion channel templates: the problem with TM4.

23 August 2017

1 reference

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Molecular dynamics and brownian dynamics investigation of ion permeation and anesthetic halothane effects on a proton-gated ion channel

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Anesthetic Binding in a Pentameric Ligand-Gated Ion Channel: GLIC

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Anesthetic sensitivity of the Gloeobacter violaceus proton-gated ion channel

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Control of cation permeation through the nicotinic receptor channel

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Scalable molecular dynamics with NAMD

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Ligand-gated ion channels: mechanisms underlying ion selectivity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

The effects of general anaesthetics on ligand-gated ion channels

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

VMD: visual molecular dynamics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

A single amino acid in gamma-aminobutyric acid rho 1 receptors affects competitive and noncompetitive components of picrotoxin inhibition

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Molecular and cellular mechanisms of general anaesthesia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

A study of the action of picrotoxin on the inhibitory neuromuscular junction of the crayfish

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Cys-loop receptor channel blockers also block GLIC.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

A single ring of charged amino acids at one end of the pore can control ion selectivity in the 5-HT3 receptor

14 September 2017

1 reference

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Mutations at the GABA receptor selectivity filter: a possible role for effective charges

14 September 2017

1 reference

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The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study.

14 September 2017

1 reference

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Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic.

23 June 2018

1 reference

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Voltage clamp recordings from Xenopus oocytes

23 June 2018

1 reference

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Adaptive biasing force method for scalar and vector free energy calculations

1 September 2018

1 reference

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Exploring the free-energy landscape of a short peptide using an average force

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Molecular determinants of picrotoxin inhibition of 5-hydroxytryptamine type 3 receptors

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Picrotoxin-mediated antagonism of alpha3beta4 and alpha7 acetylcholine receptors

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

The contribution of proline 250 (P-2') to pore diameter and ion selectivity in the human glycine receptor channel

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

The beta subunit determines the ion selectivity of the GABAA receptor

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Differential sensitivities of mammalian neuronal and muscle nicotinic acetylcholine receptors to general anesthetics.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992983

Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1042%2FBJ20121072

Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22978431

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20121072

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22978431%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

22978431

1 reference