(Q37713032)

English

Expression of the essential Kinase PfCDPK1 from Plasmodium falciparum in Toxoplasma gondii facilitates the discovery of novel antimalarial drugs

scientific article published on 18 February 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Expression of the essential Kinase PfCDPK1 from Plasmodium falciparum in Toxoplasma gondii facilitates the discovery of novel antimalarial drugs (English)

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Toxoplasma gondii

0 references

Plasmodium falciparum

0 references

0 references

author name string

Rajshekhar Y Gaji

1

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Lisa Checkley

2

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Michael L Reese

3

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Michael T Ferdig

4

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Gustavo Arrizabalaga

5

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

language of work or name

0 references

publication date

18 February 2014

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

58

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

2598-2607

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress

1 reference

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Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993251

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Inhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development

1 reference

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Conditional genome engineering in Toxoplasma gondii uncovers alternative invasion mechanisms.

1 reference

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TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993251

23 August 2017

A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993251

23 August 2017

Distinct signalling pathways control Toxoplasma egress and host-cell invasion

1 reference

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A Plasmodium calcium-dependent protein kinase controls zygote development and transmission by translationally activating repressed mRNAs

1 reference

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23 August 2017

Novel insights into the regulation of malarial calcium-dependent protein kinase 1

1 reference

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Subcellular location, phosphorylation and assembly into the motor complex of GAP45 during Plasmodium falciparum schizont development

1 reference

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Comprehensive analysis of kinase inhibitor selectivity

1 reference

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Forward targeting of Toxoplasma gondii proproteins to the micronemes involves conserved aliphatic amino acids

1 reference

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Cell cycle-dependent, intercellular transmission of Toxoplasma gondii is accompanied by marked changes in parasite gene expression

1 reference

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23 August 2017

Functional dissection of the apicomplexan glideosome molecular architecture

1 reference

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Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium

1 reference

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23 August 2017

Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors

1 reference

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Calcium-dependent signaling and kinases in apicomplexan parasites

1 reference

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Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells.

1 reference

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23 August 2017

The motor complex of Plasmodium falciparum: phosphorylation by a calcium-dependent protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993251

23 August 2017

Calcium regulation and signaling in apicomplexan parasites.

1 reference

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23 August 2017

Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility

1 reference

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23 August 2017

Comparative protein structure modeling using Modeller

1 reference

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23 August 2017

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

1 reference

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23 August 2017

Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue

1 reference

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A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii

1 reference

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The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants

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Plants, symbiosis and parasites: a calcium signalling connection

1 reference

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23 August 2017

Export of Plasmodium falciparum calcium-dependent protein kinase 1 to the parasitophorous vacuole is dependent on three N-terminal membrane anchor motifs

1 reference

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Toxoplasma gondii: the model apicomplexan.

1 reference

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Genetic complementation in apicomplexan parasites

1 reference

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Host cell invasion by the opportunistic pathogen Toxoplasma gondii

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Ionophore-resistant mutants of Toxoplasma gondii reveal host cell permeabilization as an early event in egress

1 reference

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Lytic cycle of Toxoplasma gondii

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Identifiers

10.1128/AAC.02261-13

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

ResearchGate publication ID

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