(Q41943991)

English

Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine

scientific article published on 5 December 2006

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scholarly article

1 reference

Europe PubMed Central

14 October 2017

Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine (English)

1 reference

Europe PubMed Central

14 October 2017

Plasmodium falciparum

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transmembrane protein

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7

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Europe PubMed Central

14 October 2017

author name string

Roland A Cooper

1

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Europe PubMed Central

14 October 2017

Kristin D Lane

2

1 reference

Europe PubMed Central

14 October 2017

Bingbing Deng

3

1 reference

Europe PubMed Central

14 October 2017

Jianbing Mu

4

1 reference

Europe PubMed Central

14 October 2017

Jigar J Patel

5

1 reference

Europe PubMed Central

14 October 2017

Thomas E Wellems

6

1 reference

Europe PubMed Central

14 October 2017

Michael T Ferdig

8

1 reference

Europe PubMed Central

14 October 2017

language of work or name

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publication date

5 December 2006

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Europe PubMed Central

14 October 2017

Molecular Microbiology

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Europe PubMed Central

14 October 2017

63

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Europe PubMed Central

14 October 2017

270-282

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Europe PubMed Central

14 October 2017

1

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Europe PubMed Central

14 October 2017

Some quantitative uses of drug antagonists

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Effectiveness of antimalarial drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

A Method for Testing for Synergy with Any Number of Agents

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

pfcrt is more than the Plasmodium falciparum chloroquine resistance gene: a functional and evolutionary perspective

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

A molecular marker for chloroquine-resistant falciparum malaria

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Contribution of the pfmdr1 gene to antimalarial drug-resistance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Variations in the sequence and expression of the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) and their relationship to chloroquine resistance in vitro

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Dissecting the loci of low-level quinine resistance in malaria parasites

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Quinine and chloroquine antagonism in falciparum malaria

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Stereoselective transport of hydrophilic quaternary drugs by human MDR1 and rat Mdr1b P-glycoproteins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Evidence for a Central Role for PfCRT in Conferring Plasmodium falciparum Resistance to Diverse Antimalarial Agents

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Stereoelectronic features of the cinchona alkaloids determine their differential antimalarial activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Energy dependence of chloroquine accumulation and chloroquine efflux in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Plasmodium falciparum: modulation by calcium antagonists of resistance to chloroquine, desethylchloroquine, quinine, and quinidine in vitro

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

A simple method for displaying the hydropathic character of a protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Stereospecificity in binding studies. A useful criterion though insufficient to prove the presence of receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

The malaria parasite's chloroquine resistance transporter is a member of the drug/metabolite transporter superfamily

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Multiple transporters associated with malaria parasite responses to chloroquine and quinine

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Dictyostelium discoideum expresses a malaria chloroquine resistance mechanism upon transfection with mutant, but not wild-type, Plasmodium falciparum transporter PfCRT.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

The structure of malaria pigment beta-haematin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Variations in frequencies of drug resistance in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Cloning of naturally occurring mixed infections of malaria parasites.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Role for the plasmodium falciparum digestive vacuole in chloroquine resistance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Evidence for a substrate specific and inhibitable drug efflux system in chloroquine resistant Plasmodium falciparum strains

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Evidence for a pfcrt-associated chloroquine efflux system in the human malarial parasite Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Antagonism of chloroquine with other antimalarials

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

On the molecular mechanism of chloroquine's antimalarial action

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

The principal chloroquine resistance protein of Plasmodium falciparum is a member of the drug/metabolite transporter superfamily

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Ion channels as pharmacologic receptors: the chirality of drug interactions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

pfcrt Polymorphism and the spread of chloroquine resistance in Plasmodium falciparum populations across the Amazon Basin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Lysosomes and drug resistance in malaria

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Reversal agent inhibition of the multidrug resistance pump in human leukemic lymphoblasts.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Susceptibility of human malaria parasites to chloroquine is pH dependent

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Protein volume in solution

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

The antimalarial drug resistance protein Plasmodium falciparum chloroquine resistance transporter binds chloroquine

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05511.X

21 January 2018

Identifiers

10.1111/J.1365-2958.2006.05511.X

1 reference

Europe PubMed Central

14 October 2017

1 reference

Europe PubMed Central

14 October 2017

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