(Q37715596)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24458359%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1α and MED1 complex (English)

1 reference

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6 March 2020

0 references

2

1 reference

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6 March 2020

6

Steven P Gygi

1 reference

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6 March 2020

5

Mark P Jedrychowski

1 reference

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6 March 2020

author name string

Mitsuhisa Tabata

1

1 reference

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6 March 2020

Jessica A Hall

3

1 reference

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6 March 2020

Yoonjin Lee

4

1 reference

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6 March 2020

Pere Puigserver

7

1 reference

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6 March 2020

language of work or name

English

0 references

publication date

23 January 2014

1 reference

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6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24458359%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

volume

63

1 reference

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6 March 2020

issue

5

1 reference

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6 March 2020

page(s)

1519-1532

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24458359%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

6 March 2020

copyright license

start time

30 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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23 August 2017

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Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase

23 August 2017

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Phosphorylation of CLK2 at Serine 34 and Threonine 127 by AKT Controls Cell Survival after Ionizing Radiation

23 August 2017

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23 August 2017

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Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis

23 August 2017

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Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression

23 August 2017

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Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.

23 August 2017

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23 August 2017

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Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

23 August 2017

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Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway

23 August 2017

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Fuel metabolism in starvation

23 August 2017

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Transcriptional regulation of metabolism

23 August 2017

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23 August 2017

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Medium-chain acyl-CoA dehydrogenase deficiency in gene-targeted mice

23 August 2017

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A molecular link between SR protein dephosphorylation and mRNA export

23 August 2017

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Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

23 August 2017

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Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha

23 August 2017

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23 August 2017

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Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

23 August 2017

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23 August 2017

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CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

23 August 2017

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Activation of PPARgamma coactivator-1 through transcription factor docking

23 August 2017

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A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders

23 August 2017

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Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

23 August 2017

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The cellular localization of the murine serine/arginine-rich protein kinase CLK2 is regulated by serine 141 autophosphorylation

23 August 2017

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The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing

23 August 2017

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SR proteins and splicing control

23 August 2017

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Characterization by cDNA cloning of two new human protein kinases. Evidence by sequence comparison of a new family of mammalian protein kinases

23 August 2017

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23 August 2017

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Regulation of hepatic fatty acid oxidation and ketone body production

23 August 2017

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23 August 2017

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6 September 2017

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The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

6 September 2017

1 reference

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mTORC1 controls fasting-induced ketogenesis and its modulation by ageing.

6 September 2017

1 reference

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Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994960

Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator-activated receptor alpha in HepG2 cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994960

Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994960

Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994960

Peroxisome proliferator-activated receptor alpha target genes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994960

Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994960

1 September 2018

Identifiers

DOI

10.2337/DB13-1304

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24458359%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24458359%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

24458359

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24458359%20AND%20SRC:MED&resulttype=core&format=json