(Q37727184)

22 August 2017

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title

Analysis of NF-kappaB signaling pathways by proteomic approaches (English)

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22 August 2017

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Ellen Niederberger

1

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22 August 2017

Gerd Geisslinger

series ordinal

2

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22 August 2017

publication date

1 April 2010

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Expert Review of Proteomics

22 August 2017

published in

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22 August 2017

volume

7

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22 August 2017

issue

2

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22 August 2017

page(s)

189-203

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The IKK NF-kappa B system: a treasure trove for drug development

22 August 2017

cites work

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IkappaB kinases: key regulators of the NF-kappaB pathway

21 January 2018

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Activators and target genes of Rel/NF-kappaB transcription factors

21 January 2018

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Regulation and function of IKK and IKK-related kinases

21 January 2018

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Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

21 January 2018

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IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

21 January 2018

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Triggering the interferon antiviral response through an IKK-related pathway

21 January 2018

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IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

21 January 2018

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Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding [...]

21 January 2018

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IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation

21 January 2018

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Inducible phosphorylation of NF-kappa B p65 at serine 468 by T cell costimulation is mediated by IKK epsilon.

21 January 2018

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Nuclear factor kappaB: a potential therapeutic target in atherosclerosis and thrombosis

21 January 2018

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Distinct roles for the NF-kappaB1 (p50) and c-Rel transcription factors in inflammatory arthritis

21 January 2018

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Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression

21 January 2018

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Current insights into the regulation of programmed cell death by NF-kappaB.

21 January 2018

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21 January 2018

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Proteomics: new perspectives, new biomedical opportunities

21 January 2018

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Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors

21 January 2018

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2D differential in-gel electrophoresis for the identification of esophageal scans cell cancer-specific protein markers

21 January 2018

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Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons

21 January 2018

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Approaches for systematic proteome exploration

21 January 2018

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Multidimensional separations-based shotgun proteomics

21 January 2018

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Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front

21 January 2018

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Analyzing proteome topology and function by automated multidimensional fluorescence microscopy

21 January 2018

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Toponomics analysis of drug-induced changes in arachidonic acid-dependent signaling pathways during spinal nociceptive processing

21 January 2018

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The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest

21 January 2018

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The tandem affinity purification (TAP) method: a general procedure of protein complex purification

21 January 2018

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A generic protein purification method for protein complex characterization and proteome exploration

21 January 2018

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Charting protein complexes, signaling pathways, and networks in the immune system

21 January 2018

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Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

21 January 2018

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Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

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IKK1-deficient mice exhibit abnormal development of skin and skeleton

21 January 2018

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

21 January 2018

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Lack of NF-kappaB p50 exacerbates degeneration of hippocampal neurons after chemical exposure and impairs learning

21 January 2018

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Nuclear and cytoplasmic peroxiredoxin-1 differentially regulate NF-kappaB activities

21 January 2018

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Therapeutic potential of vitamin D-binding protein

21 January 2018

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Proteomic analysis of brain protein expression levels in NF-kappabeta p50 -/- homozygous knockout mice

21 January 2018

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Brain proteome of mice lacking the receptors for tumor necrosis factor alpha

21 January 2018

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A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

21 January 2018

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The endothelium in sepsis: source of and a target for inflammation

21 January 2018

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Lipopolysaccharide-stimulated responses in rat aortic endothelial cells by a systems biology approach

21 January 2018

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In vivo dual-tagging proteomic approach in studying signaling pathways in immune response

21 January 2018

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Quantitative proteomics analysis of macrophage rafts reveals compartmentalized activation of the proteasome and of proteasome-mediated ERK activation in response to lipopolysaccharide.

21 January 2018

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A chemokine-binding domain in the tumor necrosis factor receptor from variola (smallpox) virus

21 January 2018

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Proteomic screening of variola virus reveals a unique NF-kappaB inhibitor that is highly conserved among pathogenic orthopoxviruses

21 January 2018

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Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group

21 January 2018

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Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study

21 January 2018

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Anaplastic thyroid carcinoma: an overview

21 January 2018

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Oncogenic and anti-apoptotic activity of NF-kappa B in human thyroid carcinomas

21 January 2018

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RbAp48 is a target of nuclear factor-kappaB activity in thyroid cancer

21 January 2018

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The neutrophil gelatinase-associated lipocalin (NGAL), a NF-kappaB-regulated gene, is a survival factor for thyroid neoplastic cells

21 January 2018

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The global breast cancer burden: variations in epidemiology and survival.

21 January 2018

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Fibroblast growth factors

21 January 2018

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Tyrosine kinase signalling in breast cancer: fibroblast growth factors and their receptors

21 January 2018

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The antiapoptotic effect of fibroblast growth factor-2 is mediated through nuclear factor-kappaB activation induced via interaction between Akt and IkappaB kinase-beta in breast cancer cells.

21 January 2018

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Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics

21 January 2018

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Signal transduction pathways of mantle cell lymphoma: a phosphoproteome-based study.

21 January 2018

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Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma

21 January 2018

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Proteasome inhibition with bortezomib: a new therapeutic strategy for non-Hodgkin's lymphoma

21 January 2018

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Induction of apoptosis in Jeko-1 mantle cell lymphoma cell line by resveratrol: a proteomic analysis

21 January 2018

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Resveratrol: from grapevines to mammalian biology

21 January 2018

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Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.

21 January 2018

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Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin's lymphoma and multiple myeloma cell lines to paclitaxel-induced apoptosis

21 January 2018

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Calcium-dependent regulation of tumour necrosis factor-alpha receptor signalling by copine

21 January 2018

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Molecular basis of chemoprevention by resveratrol: NF-kappaB and AP-1 as potential targets

21 January 2018

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Enhanced nuclear factor-kappa B-associated Wnt-1 expression in hepatitis B- and C-related hepatocarcinogenesis: identification by functional proteomics

21 January 2018

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Wnt signalling in stem cells and cancer

21 January 2018

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Morphoproteomics: exposing protein circuitries in tumors to identify potential therapeutic targets in cancer patients

21 January 2018

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Oesophageal cancer: new developments in systemic therapy

21 January 2018

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Antibody-based proteomics for esophageal cancer: Identification of proteins in the nuclear factor-kappaB pathway and mitotic checkpoint

21 January 2018

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NAK is an IkappaB kinase-activating kinase

21 January 2018

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Estimates of the cancer incidence and mortality in Europe in 2006.

21 January 2018

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Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen

21 January 2018

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Integrative genomic approaches identify IKBKE as a breast cancer oncogene

21 January 2018

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Immunohistochemical analysis of NF-kappaB signaling proteins IKKepsilon, p50/p105, p52/p100 and RelA in prostate cancers

21 January 2018

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Proteomics analysis in post-transplant lymphoproliferative disorders

21 January 2018

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Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation

21 January 2018

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Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation

21 January 2018

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Effects of TCDD upon IkappaB and IKK subunits localized in microsomes by proteomics

21 January 2018

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Nuclear factor-kappaB activation: from bench to bedside

21 January 2018

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Evaluation of data-dependent versus targeted shotgun proteomic approaches for monitoring transcription factor expression in breast cancer

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/EPR.10.1

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22 August 2017

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