(Q37731521)

22 August 2017

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title

Current challenges in antimicrobial chemotherapy: focus on ß-lactamase inhibition (English)

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22 August 2017

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Carine Bebrone

1

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22 August 2017

Patricia Lassaux

2

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22 August 2017

Lionel Vercheval

3

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22 August 2017

Jean-Sébastien Sohier

4

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22 August 2017

Adrien Jehaes

5

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22 August 2017

Eric Sauvage

6

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22 August 2017

Moreno Galleni

7

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22 August 2017

1 April 2010

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22 August 2017

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22 August 2017

70

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22 August 2017

6

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22 August 2017

651-679

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https://scigraph.springernature.com/pub.10.2165/11318430-000000000-00000

22 August 2017

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cites work

The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

A comparative study of class-D beta-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Cloning and sequencing of the class B beta-lactamase gene (ccrA) from Bacteroides fragilis TAL3636.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Transferable imipenem resistance in Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Molecular characterization of an enterobacterial metallo beta-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Characterization and sequence of the Chryseobacterium (Flavobacterium) meningosepticum carbapenemase: a new molecular class B beta-lactamase showing a broad substrate profile

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Clavulanic acid: a beta-lactamase-inhiting beta-lactam from Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Clavulanic Acid, a Novel Inhibitor of β-Lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Antibacterial characteristics of YTR 830, a sulfone beta-lactamase inhibitor, compared with those of clavulanic acid and sulbactam

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Comparative activity of beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with beta-lactams against beta-lactamase-producing anaerobes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Comparative evaluation of a new beta-lactamase inhibitor, YTR 830, combined with different beta-lactam antibiotics against bacteria harboring known beta-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Molecular characterization of nine different types of mutants among 107 inhibitor-resistant TEM beta-lactamases from clinical isolates of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Extended-spectrum and inhibitor-resistant TEM-type beta-lactamases: mutations, specificity, and three-dimensional structure

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Characterization of a new TEM-type beta-lactamase resistant to clavulanate, sulbactam, and tazobactam in a clinical isolate of Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

6 β-Bromopenicillanic acid inactivates β-lactamase I

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Delta 2- and delta 3-cephalosporins, penicillinate and 6-unsubstituted penems. Intrinsic reactivity and interaction with beta-lactamases and D-alanyl-D-alanine-cleaving serine peptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

beta-Lactamase inhibitory activity of iodopenicillanate and bromopenicillanate

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Synthesis of 3-Substituted-clavams: Antifungal Properties, DD-Peptidase and beta-Lactamase Inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Inhibition of class C beta-lactamases by (1'R,6R)-6-(1'-hydroxy)benzylpenicillanic acid SS-dioxide

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Kinetic study of interaction between BRL 42715, beta-lactamases, and D-alanyl-D-alanine peptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

In vitro evaluation of BRL 42715, a novel beta-lactamase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Phosphonate monoester inhibitors of class A beta-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Reversible inhibitors of penicillinases

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Diketene analogs as beta-lactamase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11318430-000000000-00000

Beta-lactamase inhibitors are substrates for the multidrug efflux pumps of Pseudomonas aeruginosa

21 January 2018

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12 December 2020

Inhibition of the broad spectrum nonmetallocarbapenamase of class A (NMC-A) beta-lactamase from Enterobacter cloacae by monocyclic beta-lactams.

1 reference

12 December 2020

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12 December 2020

Preferential selection of IMP and VIM metallo-beta-lactamases by imipenem in Pseudomonas aeruginosa.

1 reference

12 December 2020

In vitro and in vivo activities of Syn2190, a novel beta-lactamase inhibitor

1 reference

12 December 2020

Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum beta-lactamase inhibitors: evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods.

1 reference

12 December 2020

The synthesis and SAR of rhodanines as novel class C beta-lactamase inhibitors

1 reference

12 December 2020

The activity of a sulphone beta-lactamase inhibitor, YTR 830

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12 December 2020

Expansion of the zinc metallo-hydrolase family of the beta-lactamase fold

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12 December 2020

Analysis of the importance of the metallo-beta-lactamase active site loop in substrate binding and catalysis

1 reference

12 December 2020

Screening of some medicinal plants from cameroon for beta-lactamase inhibitory activity

1 reference

12 December 2020

In vitro and in vivo activities of AM-112, a novel oxapenem.

1 reference

12 December 2020

AmpD, essential for both beta-lactamase regulation and cell wall recycling, is a novel cytosolic N-acetylmuramyl-L-alanine amidase

1 reference

12 December 2020

Kinetics and mechanism of inhibition of a serine beta-lactamase by O-aryloxycarbonyl hydroxamates

1 reference

12 December 2020

O-aryloxycarbonyl hydroxamates: new beta-lactamase inhibitors that cross-link the active site

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12 December 2020

Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae

1 reference

12 December 2020

Nanomolar inhibitors of AmpC beta-lactamase

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12 December 2020

The AmpC inhibitor, Syn2190, can be used to reveal extended-spectrum beta-lactamases in Escherichia coli.

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12 December 2020

Clavulanate and beta-lactamase induction.

1 reference

12 December 2020

Clavulanate induces expression of the Pseudomonas aeruginosa AmpC cephalosporinase at physiologically relevant concentrations and antagonizes the antibacterial activity of ticarcillin

1 reference

12 December 2020

Simple disk-based method for detection of Klebsiella pneumoniae carbapenemase-type beta-lactamase by use of a boronic acid compound.

1 reference

12 December 2020

Tertiary structural similarity between a class A beta-lactamase and a penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase

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12 December 2020

Beta-lactamase genes of the penicillin-susceptible Bacillus anthracis Sterne strain

1 reference

12 December 2020

Evaluation of boronic acid disk tests for differentiating KPC-possessing Klebsiella pneumoniae isolates in the clinical laboratory

1 reference

12 December 2020

Structural Basis of the Inhibition of Class A β-Lactamases and Penicillin-Binding Proteins by 6-β-Iodopenicillanate

1 reference

12 December 2020

Pseudomonas aeruginosa - a phenomenon of bacterial resistance

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12 December 2020

Molecular characterization of OXA-20, a novel class D beta-lactamase, and its integron from Pseudomonas aeruginosa

1 reference

12 December 2020

Interaction between class B beta-lactamases and suicide substrates of active-site serine beta-lactamases

1 reference

12 December 2020

Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases

1 reference

12 December 2020

Inhibition of OXA-1 beta-lactamase by penems

1 reference

12 December 2020

OXA-18, a class D clavulanic acid-inhibited extended-spectrum beta-lactamase from Pseudomonas aeruginosa.

1 reference

12 December 2020

SYN-1012: a new beta-lactamase inhibitor of penem skeleton

1 reference

12 December 2020

ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type

1 reference

12 December 2020

Approaches to the simultaneous inactivation of metallo- and serine-beta-lactamases

1 reference

12 December 2020

Novel imidazole substituted 6-methylidene-penems as broad-spectrum beta-lactamase inhibitors

1 reference

12 December 2020

Inhibition of Class A and Class C β-Lactamases by Penems: Crystallographic Structures of a Novel 1,4-Thiazepine Intermediate,

1 reference

12 December 2020

Use of boronic acid disk tests to detect extended- spectrum beta-lactamases in clinical isolates of KPC carbapenemase-possessing enterobacteriaceae

1 reference

12 December 2020

Molecular diversity and evolution of blaTEM genes encoding beta-lactamases resistant to clavulanic acid in clinical E. coli.

1 reference

12 December 2020

High-level expression of chromosomally encoded SHV-1 beta-lactamase and an outer membrane protein change confer resistance to ceftazidime and piperacillin-tazobactam in a clinical isolate of Klebsiella pneumoniae

1 reference

12 December 2020

Standard numbering scheme for class B beta-lactamases

1 reference

12 December 2020

Distribution of beta-lactamases in Acinetobacter baumannii clinical isolates and the effect of Syn 2190 (AmpC inhibitor) on the MICs of different beta-lactam antibiotics

1 reference

12 December 2020

OXA-24, a novel class D beta-lactamase with carbapenemase activity in an Acinetobacter baumannii clinical strain

1 reference

12 December 2020

ZINC--a free database of commercially available compounds for virtual screening

1 reference

12 December 2020

Strategic Design of an Effective -Lactamase Inhibitor: LN-1-255, A 6-ALKYLIDENE-2'-SUBSTITUTED PENICILLIN SULFONE

1 reference

12 December 2020

On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target

1 reference

12 December 2020

Inhibition of beta-lactamases by monocyclic acyl phosph(on)ates

1 reference

12 December 2020

Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog

1 reference

12 December 2020

The synthesis and evaluation of 2-substituted-7-(alkylidene)cephalosporin sulfones as beta-lactamase inhibitors

1 reference

12 December 2020

Binding of D- and L-captopril inhibitors to metallo-beta-lactamase studied by polarizable molecular mechanics and quantum mechanics

1 reference

12 December 2020

Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the foss of an outer membrane protein.

1 reference

12 December 2020

The binding of boronic acids to chymotrypsin.

1 reference

12 December 2020

Force field design and molecular dynamics simulations of the carbapenem- and cephamycin-resistant dinuclear zinc metallo-beta-lactamase from Bacteroides fragilis and its complex with a biphenyl tetrazole inhibitor

1 reference

12 December 2020

Penicillinase active sites: Labelling of serine-44 in β-lactamase I by 6β-bromopenicillanic acid

1 reference

12 December 2020

A sensitive coupled HPLC/electrospray mass spectrometry assay for SPM-1 metallo-beta-lactamase inhibitors

1 reference

12 December 2020

Inhibition of serine beta-lactamases by vanadate-catechol complexes

1 reference

12 December 2020

beta-Lactamase epidemiology and the utility of established and novel beta-lactamase inhibitors

1 reference

12 December 2020

Efficient inhibition of class A and class D beta-lactamases by Michaelis complexes

1 reference

12 December 2020

In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor

1 reference

12 December 2020

Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies

1 reference

12 December 2020

Design, synthesis, and evaluation of alpha-ketoheterocycles as class C beta-lactamase inhibitors

1 reference

12 December 2020

Updated functional classification of beta-lactamases

1 reference

12 December 2020

Izumenolide-a novel beta-lactamase inhibitor produced by Micromonospora. II. Biological properties.

1 reference

12 December 2020

CTX-M-type beta-lactamases: an emerging group of extended-spectrum enzymes.

1 reference

12 December 2020

Update of the standard numbering scheme for class B beta-lactamases

1 reference

12 December 2020

High-performance liquid chromatographic determination of a new beta-lactamase inhibitor and its metabolite in combination therapy with piperacillin in biological materials

1 reference

12 December 2020

Identification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-beta-lactamases

1 reference

12 December 2020

Optimizing cell permeation of an antibiotic resistance inhibitor for improved efficacy

1 reference

12 December 2020

Variety of beta-lactamases produced by amoxicillin-clavulanate-resistant Escherichia coli isolated in the northeastern United States

1 reference

12 December 2020

Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors

1 reference

12 December 2020

Synthesis and evaluation of 3-(carboxymethylidene)- and 3-(carboxymethyl)penicillinates as inhibitors of beta-lactamase

1 reference

12 December 2020

Carbapenem derivatives as potential inhibitors of various beta-lactamases, including class B metallo-beta-lactamases.

1 reference

12 December 2020

Beta-ketophosphonates as beta-lactamase inhibitors: Intramolecular cooperativity between the hydrophobic subsites of a class D beta-lactamase

1 reference

12 December 2020

Evaluation of penicillin-based inhibitors of the class A and B beta-lactamases from Bacillus anthracis

1 reference

12 December 2020

Metallo-beta-lactamases (classification, activity, genetic organization, structure, zinc coordination) and their superfamily

1 reference

12 December 2020

Influence of gene dosing on antibiotic resistance mediated by inactivating enzymes.

1 reference

12 December 2020

IRT and CMT beta-lactamases and inhibitor resistance

1 reference

12 December 2020

Interactions of tazobactam and clavulanate with inducibly- and constitutively-expressed Class I beta-lactamases.

1 reference

12 December 2020

Permeability of a novel beta-lactamase inhibitor LK-157 and its ester prodrugs across rat jejunum in vitro

1 reference

12 December 2020

The synthesis and evaluation of 6-alkylidene-2'beta-substituted penam sulfones as beta-lactamase inhibitors.

1 reference

12 December 2020

Establishment of in vitro susceptibility testing methodologies and comparative activities of piperacillin in combination with the penem {beta}-lactamase inhibitor BLI-489.

1 reference

12 December 2020

Effect of sulbactam on anti-pseudomonal activity of beta-lactam antibiotics in cells producing various levels of the MexAB-OprM efflux pump and beta-lactamase

1 reference

12 December 2020

Synergy of amoxycillin combined with clavulanate and YTR 830 in experimental infections in mice

1 reference

12 December 2020

6-(1-Hydroxyalkyl)penam sulfone derivatives as inhibitors of class A and class C beta-lactamases I.

1 reference

12 December 2020

A broad-spectrum peptide inhibitor of beta-lactamase identified using phage display and peptide arrays

1 reference

12 December 2020

Dynamics of the metallo-beta-lactamase from Bacteroides fragilis in the presence and absence of a tight-binding inhibitor

1 reference

12 December 2020

Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor

1 reference

12 December 2020

Comparative evaluation of the inhibitory activities of the novel penicillanic acid sulfone Ro 48-1220 against beta-lactamases that belong to groups 1, 2b, and 2be.

1 reference

12 December 2020

6-beta-bromopenicillanic acid, a potent beta-lactamase inhibitor

1 reference

12 December 2020

beta-Lactam resistance phenotype determination in Escherichia coli isolates from University Malaya Medical Centre.

1 reference

12 December 2020

Inhibitors of metallo-beta-lactamase generated from beta-lactam antibiotics.

1 reference

12 December 2020

Design, synthesis, and evaluation of 2 beta-alkenyl penam sulfone acids as inhibitors of beta-lactamases

1 reference

12 December 2020

NXL104 combinations versus Enterobacteriaceae with CTX-M extended-spectrum beta-lactamases and carbapenemases

1 reference

12 December 2020

4-Substituted trinems as broad spectrum beta-lactamase inhibitors: structure-based design, synthesis, and biological activity

1 reference

12 December 2020

Competitive Inhibitors of the CphA Metallo- -Lactamase from Aeromonas hydrophila

1 reference

12 December 2020

A complex mutant of TEM-1 beta-lactamase with mutations encountered in both IRT-4 and extended-spectrum TEM-15, produced by an Escherichia coli clinical isolate.

1 reference

12 December 2020

Structure-based optimization of a non-beta-lactam lead results in inhibitors that do not up-regulate beta-lactamase expression in cell culture

1 reference

12 December 2020

Mechanism of reaction of acyl phosph(on)ates with the beta-lactamase of Enterobacter cloacae P99.

1 reference

12 December 2020

Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase

1 reference

12 December 2020

Studies on ternary metallo-beta lactamase-inhibitor complexes using electrospray ionization mass spectrometry.

1 reference

12 December 2020

The inhibitor thiomandelic acid binds to both metal ions in metallo-beta-lactamase and induces positive cooperativity in metal binding

1 reference

12 December 2020

Klebsiella pneumoniae Carbapenemase-2, Buenos Aires, Argentina

1 reference

12 December 2020

Factors determining resistance to beta-lactam combined with beta-lactamase inhibitors in Escherichia coli

1 reference

12 December 2020

A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem

1 reference

12 December 2020

A specific peptide inhibitor of the class B metallo-beta-lactamase L-1 from Stenotrophomonas maltophilia identified using phage display

1 reference

12 December 2020

Precise insertion of antibiotic resistance determinants into Tn21-like transposons: nucleotide sequence of the OXA-1 beta-lactamase gene

1 reference

12 December 2020

Inhibitor-resistant TEM beta-lactamases: phenotypic, genetic and biochemical characteristics

1 reference

12 December 2020

Novel IMP-1 metallo-beta-lactamase inhibitors can reverse meropenem resistance in Escherichia coli expressing IMP-1.

1 reference

12 December 2020

In vitro activities of novel oxapenems, alone and in combination with ceftazidime, against gram-positive and gram-negative organisms

1 reference

12 December 2020

The synthesis and evaluation of 3-substituted-7-(alkylidene)cephalosporin sulfones as beta-lactamase inhibitors

1 reference

12 December 2020

Raman crystallographic studies of the intermediates formed by Ser130Gly SHV, a beta-lactamase that confers resistance to clinical inhibitors.

1 reference

12 December 2020

Dramatic broadening of the substrate profile of the Aeromonas hydrophila CphA metallo-beta-lactamase by site-directed mutagenesis

1 reference

12 December 2020

Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia

1 reference

12 December 2020

Antibiotic sensitization using biphenyl tetrazoles as potent inhibitors of Bacteroides fragilis metallo-beta-lactamase

1 reference

12 December 2020

Docking for fragment inhibitors of AmpC -lactamase

1 reference

12 December 2020

Rational design of a beta-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 A crystal structure of wt SHV-1 complex with a penam sulfone

1 reference

12 December 2020

NMR characterization of the metallo-beta-lactamase from Bacteroides fragilis and its interaction with a tight-binding inhibitor: role of an active-site loop

1 reference

12 December 2020

Biochemical characterisation of the CTX-M-14 beta-lactamase.

1 reference

12 December 2020

Pharmacodynamics of ceftazidime plus the serine beta-lactamase inhibitor AM-112 against Escherichia coli containing TEM-1 and CTX-M-1 beta-lactamases

1 reference

12 December 2020

Effect of conalbumin on the activity of Syn 2190, a 1,5 dihydroxy-4-pyridon monobactam inhibitor of AmpC beta-lactamases.

1 reference

12 December 2020

Inhibition of class D beta-lactamases by acyl phosphates and phosphonates

1 reference

12 December 2020

Is it necessary to change the classification of {beta}-lactamases?

1 reference

12 December 2020

Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril

1 reference

12 December 2020

SB-202742, a novel beta-lactamase inhibitor isolated from Spondias mombin

1 reference

12 December 2020

Structural and kinetic characterization of a beta-lactamase-inhibitor protein

1 reference

12 December 2020

Inhibition of beta-lactamase by 1,4-naphthalenedione from the plant Holoptelea integrifolia.

1 reference

12 December 2020

Binding properties of a peptide derived from beta-lactamase inhibitory protein

1 reference

12 December 2020

Efficacy of piperacillin combined with the Penem beta-lactamase inhibitor BLI-489 in murine models of systemic infection

1 reference

12 December 2020

In vitro activity of the {beta}-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases

1 reference

12 December 2020

Hybrid QM/MM and DFT investigations of the catalytic mechanism and inhibition of the dinuclear zinc metallo-beta-lactamase CcrA from Bacteroides fragilis.

1 reference

12 December 2020

Inhibition of class C beta-lactamases: structure of a reaction intermediate with a cephem sulfone

1 reference

12 December 2020

Comparative in vitro activity of apalcillin alone and combined with Ro 48-1220, a novel penam beta-lactamase inhibitor.

1 reference

12 December 2020

Potentiation of beta-lactams against Pseudomonas aeruginosa strains by Ro 48-1256, a bridged monobactam inhibitor of AmpC beta-lactamases

1 reference

12 December 2020

The structure of β-lactamases

1 reference

12 December 2020

Inhibition of a class C beta-lactamase by a specific phosphonate monoester

1 reference

12 December 2020

Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 beta-lactamases in New York City

1 reference

12 December 2020

Mechanism and stability of hyperproduction of the extended-spectrum beta-lactamase SHV-5 in Klebsiella pneumoniae.

1 reference

12 December 2020

Structure-activity studies of the inhibition of serine beta-lactamases by phosphonate monoesters

1 reference

12 December 2020

In vitro and in vivo activities of novel 6-methylidene penems as beta-lactamase inhibitors

1 reference

12 December 2020

Structure, function, and inhibition along the reaction coordinate of CTX-M beta-lactamases

1 reference

12 December 2020

Clavulanic acid inhibition of .BETA.-lactamase I from Bacillus cereus 569/H

1 reference

12 December 2020

Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols

1 reference

12 December 2020

Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates

1 reference

12 December 2020

Complexes of thiomandelate and captopril mercaptocarboxylate inhibitors to metallo-beta-lactamase by polarizable molecular mechanics. Validation on model binding sites by quantum chemistry

1 reference

12 December 2020

Crystallographic investigation of the inhibition mode of a VIM-2 metallo-beta-lactamase from Pseudomonas aeruginosa by a mercaptocarboxylate inhibitor

1 reference

12 December 2020

Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase

1 reference

12 December 2020

Crystal structure of extended-spectrum beta-lactamase Toho-1: insights into the molecular mechanism for catalytic reaction and substrate specificity expansion

1 reference

12 December 2020

Structure and dynamics of CTX-M enzymes reveal insights into substrate accommodation by extended-spectrum beta-lactamases

1 reference

12 December 2020

5,5,6-Fused tricycles bearing imidazole and pyrazole 6-methylidene penems as broad-spectrum inhibitors of beta-lactamases

1 reference

12 December 2020

Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries

1 reference

12 December 2020

The 1.5-A structure of Chryseobacterium meningosepticum zinc beta-lactamase in complex with the inhibitor, D-captopril

1 reference

12 December 2020

Structure-based optimization of cephalothin-analogue boronic acids as β-lactamase inhibitors

1 reference

12 December 2020

Homo-cysteinyl peptide inhibitors of the L1 metallo-beta-lactamase, and SAR as determined by combinatorial library synthesis

1 reference

12 December 2020

Comprehensive Mechanistic Analysis of Hits from High-Throughput and Docking Screens against β-Lactamase

1 reference

12 December 2020

Mutation of the active site carboxy-lysine (K70) of OXA-1 beta-lactamase results in a deacylation-deficient enzyme

1 reference

12 December 2020

Cysteinyl peptide inhibitors of Bacillus cereus zinc beta-lactamase.

1 reference

12 December 2020

Critical involvement of a carbamylated lysine in catalytic function of class D -lactamases

1 reference

12 December 2020

Mechanism of inhibition of the class C beta-lactamase of Enterobacter cloacae P99 by cyclic acyl phosph(on)ates: rescue by return

1 reference

12 December 2020

In vitro activity of LK-157, a novel tricyclic carbapenem as broad-spectrum {beta}-lactamase inhibitor

1 reference

12 December 2020

Aza-boronic acids as non-beta-lactam inhibitors of AmpC-beta-lactamase.

1 reference

12 December 2020

Discovery of novel lipophilic inhibitors of OXA-10 enzyme (class D beta-lactamase) by screening amino analogs and homologs of citrate and isocitrate.

1 reference

12 December 2020

New leads of metallo-beta-lactamase inhibitors from structure-based pharmacophore design

1 reference

12 December 2020

Phenylpropynal, a specific, irreversible, non-beta-lactam inhibitor of beta-lactamases

1 reference

12 December 2020

Crystal structure of Enterobacter cloacae 908R class C beta-lactamase bound to iodo-acetamido-phenyl boronic acid, a transition-state analogue

1 reference

12 December 2020

Why clinically used tazobactam and sulbactam are poor inhibitors of OXA-10 beta-lactamase: Raman crystallographic evidence

1 reference

12 December 2020

Structure-based design of beta-lactamase inhibitors. 1. Synthesis and evaluation of bridged monobactams.

1 reference

12 December 2020

Mechanism of inhibition of the class C beta-lactamase of Enterobacter cloacae P99 by phosphonate monoesters

1 reference

12 December 2020

Sensitive screening tests for suspected class A carbapenemase production in species of Enterobacteriaceae

1 reference

12 December 2020

10.2165/11318430-000000000-00000

Identifiers

DOI

1 reference

Dimensions Publication ID

22 August 2017

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1 reference