(Q37732115)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20397369%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

review article

1 reference

title

L-methylfolate, methylcobalamin, and N-acetylcysteine in the treatment of Alzheimer's disease-related cognitive decline (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20397369%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

0 references

1 reference

Andrew McCaddon

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20397369%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Peter R Hudson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20397369%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

publication date

1 January 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20397369%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20397369%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20397369%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

issue

1 Suppl 1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20397369%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

page(s)

2-5; discussion 6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20397369%20AND%20SRC:MED&resulttype=core&format=json

Co-administration of N-acetylcysteine, vitamin B12 and folate in cognitively impaired hyperhomocysteinaemic patients

31 January 2020

cites work

1 reference

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7 January 2021

The treatment of hyperhomocysteinemia

1 reference

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7 January 2021

A novel role for vitamin B(12): Cobalamins are intracellular antioxidants in vitro

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7 January 2021

Vitamin B(12) and redox homeostasis: cob(II)alamin reacts with superoxide at rates approaching superoxide dismutase (SOD)

1 reference

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7 January 2021

A human vitamin B12 trafficking protein uses glutathione transferase activity for processing alkylcobalamins

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7 January 2021

Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38delta at Thr50 promotes microtubule assembly.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Homocysteine induces tau phosphorylation by inactivating protein phosphatase 2A in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Is hyperhomocysteinemia due to the oxidative depletion of folate rather than to insufficient dietary intake?

1 reference

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7 January 2021

Protein phosphatase 2A methylation: a link between elevated plasma homocysteine and Alzheimer's Disease

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7 January 2021

Possible role of amyloid-beta, adenine nucleotide translocase and cyclophilin-D interaction in mitochondrial dysfunction of Alzheimer's disease

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7 January 2021

Oxidative stress, mitochondrial dysfunction, and stress signaling in Alzheimer's disease

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7 January 2021

Non-cholinergic strategies for treating and preventing Alzheimer's disease

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7 January 2021

Crystal structure and mutagenesis of the metallochaperone MeaB: insight into the causes of methylmalonic aciduria

1 reference

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7 January 2021

Homocysteine, folate and vitamin B12 in neuropsychiatric diseases: review and treatment recommendations

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7 January 2021

THE METHYL FOLATE TRAP A physiological response in man to prevent methyl group deficiency in kwashiorkor (methionine deficiency) and an explanation for folic-acid-induced exacerbation of subacute combined degeneration in pernicious anaemia

1 reference

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7 January 2021

Amyloid-beta aggregation

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7 January 2021

Compensatory responses induced by oxidative stress in Alzheimer disease

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7 January 2021

Contributions of hyperhomocysteinemia to atherosclerosis: Causal relationship and potential mechanisms

1 reference

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7 January 2021

Efficacy of a vitamin/nutriceutical formulation for early-stage Alzheimer's disease: a 1-year, open-label pilot study with an 16-month caregiver extension

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Methylmalonic acid and cognitive function in the Medical Research Council Cognitive Function and Ageing Study.

1 reference

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7 January 2021

Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Mitochondrial accumulation of APP and Abeta: significance for Alzheimer disease pathogenesis

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Cobalamin-dependent methionine synthase

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Hyperhomocysteinemia increases beta-amyloid by enhancing expression of gamma-secretase and phosphorylation of amyloid precursor protein in rat brain

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Tau phosphorylation: physiological and pathological consequences

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Choline and cholinergic neurons

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Genetic and cellular studies of oxidative stress in methylmalonic aciduria (MMA) cobalamin deficiency type C (cblC) with homocystinuria (MMACHC).

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Oxidative damage in mild cognitive impairment and early Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Homocysteine and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Nutritional factors in physical and cognitive functions of elderly people

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

High prevalence of cobalamin deficiency in elderly outpatients

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Phospholipid Methylation and Biological Signal Transmission

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Vitamin B12-B6-folate treatment improves blood-brain barrier function in patients with hyperhomocysteinaemia and mild cognitive impairment

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Slowed synthesis of DNA and methionine is a pathogenetic mechanism common to dementia in Down's syndrome, AIDS and Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Identification of cognitive impairment in the elderly: homocysteine is an early marker.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.

1 reference

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7 January 2021

The worldwide challenge of the dementias: a role for B vitamins and homocysteine?

1 reference

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7 January 2021

Folate and methylation status in relation to phosphorylated tau protein(181P) and beta-amyloid(1-42) in cerebrospinal fluid.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency: a systematic review of randomized controlled trials

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Efficacy of a vitamin/nutriceutical formulation for moderate-stage to later-stage Alzheimer's disease: a placebo-controlled pilot study

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Methylmalonic acid, a biochemical hallmark of methylmalonic acidurias but no inhibitor of mitochondrial respiratory chain

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Alzheimer's disease: a 'cobalaminergic' hypothesis

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Total serum homocysteine in senile dementia of Alzheimer type

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Homocysteine and cognitive impairment; a case series in a General Practice setting

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Characterization of folate uptake by choroid plexus epithelial cells in a rat primary culture model

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Cerebrospinal fluid biomarkers for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Absence of macrocytic anaemia in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Folate deficiency induces in vitro and mouse brain region-specific downregulation of leucine carboxyl methyltransferase-1 and protein phosphatase 2A B(alpha) subunit expression that correlate with enhanced tau phosphorylation

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

The role of folic acid and Vitamin B12 in genomic stability of human cells

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

The aging of the NMDA receptor complex

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Pin1 in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Pin-pointing APP processing.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Homocysteine and cognitive decline in healthy elderly

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Release of neuroactive substances: homocysteic acid as an endogenous agonist of the NMDA receptor

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Poly(ADP-ribose) polymerase as a key player in excitotoxicity and post-ischemic brain damage.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Homocysteine and brain atrophy

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Cerebrospinal fluid biomarkers and prediction of conversion in patients with mild cognitive impairment: 4-year follow-up in a routine clinical setting.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Homocysteine and brain atrophy on MRI of non-demented elderly

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Homocysteine potentiates beta-amyloid neurotoxicity: role of oxidative stress

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Vitamin status and intake as primary determinants of homocysteinemia in an elderly population

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Controlled trial of N-acetylcysteine for patients with probable Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Elevated levels of homocysteine compromise blood-brain barrier integrity in mice

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Functional vitamin B(12) deficiency and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Treatment of Alzheimer's disease in the long-term-care setting

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Homocysteine, vitamin B12 and folate in vascular dementia and in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

N-Acetylcysteine--a safe antidote for cysteine/glutathione deficiency

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

Urinary and Plasma Homocysteine and Cysteine Levels during Prolonged Oral N-Acetylcysteine Therapy

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900027589

7 January 2021

10.1017/S1092852900027589

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20397369%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference