(Q37732551)

English

Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and development

scientific article published on 16 April 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and development (English)

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

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Trypanosoma cruzi

0 references

1 reference

based on heuristic

inferred from title

Sergio Schenkman

6

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

author name string

Carolina B Moraes

1

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Miriam A Giardini

2

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Hwayoung Kim

3

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Caio H Franco

4

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Adalberto M Araujo-Junior

5

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Eric Chatelain

7

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Lucio H Freitas-Junior

8

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

language of work or name

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publication date

16 April 2014

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Europe PubMed Central

PMC publication ID

22 August 2017

Scientific Reports

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Europe PubMed Central

PMC publication ID

22 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

4703

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

16 April 2014

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April 2022 Public Data File from Crossref

copyright status

0 references

An image-based algorithm for precise and accurate high throughput assessment of drug activity against the human parasite Trypanosoma cruzi

1 reference

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1 reference

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Complexes of Trypanosoma cruzi Sterol 14 -Demethylase (CYP51) with Two Pyridine-based Drug Candidates for Chagas Disease: STRUCTURAL BASIS FOR PATHOGEN SELECTIVITY

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1 reference

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Geographical distribution of Trypanosoma cruzi genotypes in Venezuela.

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American trypanosomiasis (Chagas disease).

1 reference

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1 reference

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Targeting Trypanosoma cruzi sterol 14α-demethylase (CYP51)

1 reference

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SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis

1 reference

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Visual genome-wide RNAi screening to identify human host factors required for Trypanosoma cruzi infection

1 reference

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23 August 2017

Discovery of novel orally bioavailable oxaborole 6-carboxamides that demonstrate cure in a murine model of late-stage central nervous system african trypanosomiasis

1 reference

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23 August 2017

Structural Insights into Inhibition of Sterol 14 -Demethylase in the Human Pathogen Trypanosoma cruzi

1 reference

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23 August 2017

Structural Characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei Bound to the Antifungal Drugs Posaconazole and Fluconazole

1 reference

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23 August 2017

A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004771

23 August 2017

Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004771

23 August 2017

The molecular epidemiology and phylogeography of Trypanosoma cruzi and parallel research on Leishmania: looking back and to the future.

1 reference

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23 August 2017

Chagas disease in Spain, the United States and other non-endemic countries

1 reference

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23 August 2017

Feasibility, drug safety, and effectiveness of etiological treatment programs for Chagas disease in Honduras, Guatemala, and Bolivia: 10-year experience of Médecins Sans Frontières

1 reference

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Genome-scale multilocus microsatellite typing of Trypanosoma cruzi discrete typing unit I reveals phylogeographic structure and specific genotypes linked to human infection

1 reference

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Side effects of benznidazole as treatment in chronic Chagas disease: fears and realities

1 reference

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A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes

1 reference

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Sterol 14-demethylase inhibitors for Trypanosoma cruzi infections.

1 reference

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The Anti-Trypanosoma cruzi activity of posaconazole in a murine model of acute Chagas' disease is less dependent on gamma interferon than that of benznidazole

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Toxic side effects of drugs used to treat Chagas' disease (American trypanosomiasis)

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A critical review on Chagas disease chemotherapy

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Activities of the triazole derivative SCH 56592 (posaconazole) against drug-resistant strains of the protozoan parasite Trypanosoma (Schizotrypanum) cruzi in immunocompetent and immunosuppressed murine hosts

1 reference

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Induction of resistance to azole drugs in Trypanosoma cruzi

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1 reference

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1 reference

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Experimental chemotherapy and approaches to drug discovery for Trypanosoma cruzi infection.

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1 reference

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Recent Developments in Sterol 14-demethylase Inhibitors for Chagas Disease.

1 reference

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Trypanosoma cruzi benznidazole susceptibility in vitro does not predict the therapeutic outcome of human Chagas disease

1 reference

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Effects of ravuconazole treatment on parasite load and immune response in dogs experimentally infected with Trypanosoma cruzi.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004771

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Trypanosoma cruzi: susceptibility to chemotherapy with benznidazole of clones isolated from the highly resistant Colombian strain

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004771

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Susceptibility and natural resistance of Trypanosoma cruzi strains to drugs used clinically in Chagas disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004771

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004771

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In vivo susceptibility to benznidazole of Trypanosoma cruzi strains from the western Brazilian Amazon

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004771

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004771

1 September 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004771

1 September 2018

An Estimate of the Burden of Chagas Disease in the United States

1 reference

https://api.crossref.org/works/10.1038%2FSREP04703

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Efficacy of chemotherapy with benznidazole in children in the indeterminate phase of Chagas' disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004771

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Trypanosoma cruzi: biological characterization of clones derived from chronic chagasic patients. II. Quantitative analysis of the intracellular cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004771

3 December 2018

Effects of amiodarone and posaconazole on the growth and ultrastructure of Trypanosoma cruzi

1 reference

https://pubmed.ncbi.nlm.nih.gov/24736467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of complete precursors for the glycosylphosphatidylinositol protein anchors of Trypanosoma cruzi

1 reference

https://pubmed.ncbi.nlm.nih.gov/24736467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP04703

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

ResearchGate publication ID

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