(Q37732655)

22 August 2017

Cyclin-dependent kinase 5 in the ventral tegmental area regulates depression-related behaviors (English)

1 reference

22 August 2017

Peng Zhong

1

1 reference

22 August 2017

Xiaojie Liu

2

1 reference

22 August 2017

Zhen Zhang

3

1 reference

22 August 2017

Ying Hu

4

1 reference

22 August 2017

Sarah J Liu

5

1 reference

22 August 2017

Martha Lezama-Ruiz

6

1 reference

22 August 2017

Milan Joksimovic

7

1 reference

22 August 2017

Qing-song Liu

8

1 reference

22 August 2017

language of work or name

English

0 references

publication date

1 April 2014

1 reference

22 August 2017

Journal of Neuroscience

1 reference

22 August 2017

34

1 reference

22 August 2017

18

1 reference

22 August 2017

6352-6366

1 reference

describes a project that uses

22 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4004818/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Forebrain-specific deletion of Cdk5 in pyramidal neurons results in mania-like behavior and cognitive impairment

23 August 2017

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Combining a dopamine agonist and selective serotonin reuptake inhibitor for the treatment of depression: a double-blind, randomized pilot study

23 August 2017

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Metabotropic glutamate receptor I (mGluR1) antagonism impairs cocaine-induced conditioned place preference via inhibition of protein synthesis

23 August 2017

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A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons.

23 August 2017

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Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

23 August 2017

1 reference

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Dopamine neurons modulate neural encoding and expression of depression-related behaviour

23 August 2017

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Regulation of N-type voltage-gated calcium channels and presynaptic function by cyclin-dependent kinase 5.

23 August 2017

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Cdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway.

23 August 2017

1 reference

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Extracellular signal-regulated kinase signaling in the ventral tegmental area mediates cocaine-induced synaptic plasticity and rewarding effects

23 August 2017

1 reference

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Remote control of neuronal signaling

23 August 2017

1 reference

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Demon voltammetry and analysis software: analysis of cocaine-induced alterations in dopamine signaling using multiple kinetic measures

23 August 2017

1 reference

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Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action

23 August 2017

1 reference

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The role of Cdk5 in cognition and neuropsychiatric and neurological pathology

23 August 2017

1 reference

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Animal models of neuropsychiatric disorders

23 August 2017

1 reference

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Attention-deficit/hyperactivity phenotype in mice lacking the cyclin-dependent kinase 5 cofactor p35

23 August 2017

1 reference

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Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress

23 August 2017

1 reference

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A chemical-genetic approach to study G protein regulation of beta cell function in vivo.

23 August 2017

1 reference

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Cyclin-dependent kinase 5 inhibitors: inhibition of dopamine transporter activity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

23 August 2017

Neurobiology of ADHD.

1 reference

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Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors

23 August 2017

1 reference

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Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models

23 August 2017

1 reference

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Elevated plus maze for mice

23 August 2017

1 reference

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CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits

23 August 2017

1 reference

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Desipramine reduces stress-activated dynorphin expression and CREB phosphorylation in NAc tissue

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Cdk5 modulates cocaine reward, motivation, and striatal neuron excitability

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

The mesolimbic dopamine reward circuit in depression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Detection technologies. Probing cellular chemistry in biological systems with microelectrodes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Tyrosine hydroxylase phosphorylation: regulation and consequences

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Cyclin-dependent kinase 5 phosphorylates serine 31 of tyrosine hydroxylase and regulates its stability

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Identification of tyrosine hydroxylase as a physiological substrate for Cdk5.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Amplification of dopaminergic signaling by a positive feedback loop

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Two types of neurone in the rat ventral tegmental area and their synaptic inputs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Depression: a new animal model sensitive to antidepressant treatments

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Cdk5: a multifaceted kinase in neurodegenerative diseases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Cyclin-dependent kinases in brain development and disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Depolarization-stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Short- and long-term regulation of tyrosine hydroxylase in chromaffin cells by VIP and PACAP.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Anxiety, defence and the elevated plus-maze

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Immunocytochemical localization of DARPP-32, a dopamine and cyclic-AMP-regulated phosphoprotein, in the primate brain

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Reduced striatal dopamine synthesis capacity is associated with symptoms of depression in patients with de novo unmedicated Parkinson's disease

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Increased Cdk5/p35 activity in the dentate gyrus mediates depressive-like behaviour in rats

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

CDK5 serves as a major control point in neurotransmitter release.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

A silver bullet for the treatment of depression?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Par-4 links dopamine signaling and depression

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Decoding dopamine signaling

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Bidirectional regulation of DARPP-32 phosphorylation by dopamine.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004818

Depression in Parkinson's disease

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24790206

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.3673-13.2014

1 reference

22 August 2017

1 reference

22 August 2017

PubMed publication ID

24790206

1 reference