(Q37737987)

22 August 2017

1 reference

title

Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease (English)

1 reference

22 August 2017

0 references

John P Driver

1

1 reference

PubMed ID

20424843

22 August 2017

David V Serreze

series ordinal

2

1 reference

PubMed ID

20424843

22 August 2017

Yi-Guang Chen

series ordinal

3

1 reference

22 August 2017

28 April 2010

1 reference

Seminars in Immunopathology

22 August 2017

1 reference

22 August 2017

33

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22 August 2017

1

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22 August 2017

67-87

1 reference

https://scigraph.springernature.com/pub.10.1007/s00281-010-0204-1

22 August 2017

0 references

cites work

TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Genetic control of autoimmune diabetes in the NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Transgenic rescue implicates beta2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Resistance alleles at two non-major histocompatibility complex-linked insulin-dependent diabetes loci on chromosome 3, Idd3 and Idd10, protect nonobese diabetic mice from diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

IL-21 signaling is critical for the development of type I diabetes in the NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Interleukin-21 is required for the development of type 1 diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Molecular scanning of interleukin-21 gene and genetic susceptibility to type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

CTLA-4 control over Foxp3+ regulatory T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Genetic evidence that the differential expression of the ligand-independent isoform of CTLA-4 is the molecular basis of the Idd5.1 type 1 diabetes region in nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Polygenic control of autoimmune diabetes in nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

During the early prediabetic period in NOD mice, the pathogenic CD8(+) T-cell population comprises multiple antigenic specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Enhanced pathogenicity of diabetogenic T cells escaping a non-MHC gene-controlled near death experience.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ regulatory T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Genes within the Idd5 and Idd9/11 diabetes susceptibility loci affect the pathogenic activity of B cells in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Localization of Idd11 is not associated with thymus and nkt cell abnormalities in NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Conditioning the genome identifies additional diabetes resistance loci in Type I diabetes resistant NOR/Lt mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Genetic analysis of the diabetes-prone C57BLKS/J mouse strain reveals genetic contribution from multiple strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Linkage of type I diabetes to 15q26 (IDDM3) in the Danish population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Genes and cellular requirements for autoimmune diabetes susceptibility in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

The enemy within: keeping self-reactive T cells at bay in the periphery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

A central role for central tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Dendritic cells in immunity and tolerance-do they display opposite functions?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Dendritic cells in a mature age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Low CD86 expression in the nonobese diabetic mouse results in the impairment of both T cell activation and CTLA-4 up-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Defects in the differentiation and function of bone marrow-derived dendritic cells in non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Dendritic cells are sufficient to cross-present self-antigens to CD8 T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Targeting CD22 reprograms B-cells and reverses autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

In vivo BLyS/BAFF neutralization ameliorates islet-directed autoimmunity in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

CD4(+)CD25(+) T-cells control autoimmunity in the absence of B-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

B cells are crucial for determinant spreading of T cell autoimmunity among beta cell antigens in diabetes-prone nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Lymphoid neogenesis in chronic inflammatory diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

B cell selection defects underlie the development of diabetogenic APCs in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Hematopoietic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: defective regulation of cytokine receptors and protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Cutting edge: the Idd3 genetic interval determines regulatory T cell function through CD11b+CD11c- APC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

The consequences of apoptosis in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

NOD macrophages produce high levels of inflammatory cytokines upon encounter of apoptotic or necrotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Nonobese diabetic mouse congenic analysis reveals chromosome 11 locus contributing to diabetes susceptibility, macrophage STAT5 dysfunction, and granulocyte-macrophage colony-stimulating factor overproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Nonobese diabetic mice and the genetics of diabetes susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Thymic T cell anergy in autoimmune nonobese diabetic mice is mediated by deficient T cell receptor regulation of the pathway of p21ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Defect in activation-induced cell death in non-obese diabetic (NOD) T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Deficient activation and resistance to activation-induced apoptosis of CD8+ T cells is associated with defective peripheral tolerance in nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Control of type 1 autoimmune diabetes by naturally occurring CD4+CD25+ regulatory T lymphocytes in neonatal NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Going both ways: immune regulation via CD1d-dependent NKT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Evidence for a differential avidity model of T cell selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Peripheral selection of the T cell repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

IL-15 and IL-2: a matter of life and death for T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Diabetes in non-obese diabetic mice is not associated with quantitative changes in CD4+ CD25+ Foxp3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

A sudden decline in active membrane-bound TGF-beta impairs both T regulatory cell function and protection against autoimmune diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Control of type 1 diabetes by CD4+Foxp3+ regulatory T cells: lessons from mouse models and implications for human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

CD1: antigen presentation and T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

A defect in interleukin 12-induced activation and interferon gamma secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Host natural killer T cells induce an interleukin-4-dependent expansion of donor CD4+CD25+Foxp3+ T regulatory cells that protects against graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Invariant natural killer T-cell control of type 1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Expansion and hyperactivity of CD1d-restricted NKT cells during the progression of systemic lupus erythematosus in (New Zealand Black x New Zealand White)F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

CD4+CD25+ regulatory T cells generated in response to insulin B:9-23 peptide prevent adoptive transfer of diabetes by diabetogenic T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Antigen-based therapy for the treatment of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Effects of insulin in relatives of patients with type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Islet-cell antigen-reactive T cells show different expansion rates and Th1/Th2 differentiation in type 1 diabetic patients and healthy controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Oral insulin administration and residual beta-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial. Diabète Insuline Orale group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

No effect of oral insulin on residual beta-cell function in recent-onset type I diabetes (the IMDIAB VII). IMDIAB Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

GAD65 vaccination: 5 years of follow-up in a randomised dose-escalating study in adult-onset autoimmune diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

GAD treatment and insulin secretion in recent-onset type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Peripheral tolerance induction using ethylenecarbodiimide-fixed APCs uses both direct and indirect mechanisms of antigen presentation for prevention of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

ECDI-fixed allogeneic splenocytes induce donor-specific tolerance for long-term survival of islet transplants via two distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Inhibition of autoimmune diabetes in nonobese diabetic mice by transgenic restoration of H2-E MHC class II expression: additive, but unequal, involvement of multiple APC subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic tolerance and reversal of autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Prevention of type 1 diabetes with major histocompatibility complex-compatible and nonmarrow ablative hematopoietic stem cell transplants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Dendritic cell immunotherapy for autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Granulocyte colony-stimulating factor promotes the generation of regulatory DC through induction of IL-10 and IFN-alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Modulation of dendritic cells using granulocyte-macrophage colony-stimulating factor (GM-CSF) delays type 1 diabetes by enhancing CD4+CD25+ regulatory T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

CD3-specific antibodies: a portal to the treatment of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Therapeutic vaccination using CD4+CD25+ antigen-specific regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Expansion of human regulatory T-cells from patients with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Modulation of insulitis and type 1 diabetes by transgenic HLA-DR3 and DQ8 in NOD mice lacking endogenous MHC class II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Autoimmune cardiomyopathy and heart block develop spontaneously in HLA-DQ8 transgenic IAbeta knockout NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Metastable pluripotent states in NOD-mouse-derived ESCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Validated germline-competent embryonic stem cell lines from nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Humanized mice in translational biomedical research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Genetic analysis of autoimmune type 1 diabetes mellitus in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

The idd4 locus displays sex-specific epistatic effects on type 1 diabetes susceptibility in nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Identification of the transcription factor ARNTL2 as a candidate gene for the type 1 diabetes locus Idd6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Diabetes protection and restoration of thymocyte apoptosis in NOD Idd6 congenic strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Genetic and functional association of the immune signaling molecule 4-1BB (CD137/TNFRSF9) with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Genetic and physiological association of diabetes susceptibility with raised Na+/H+ exchange activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Colocalization of Mouse Autoimmune Diabetes Loci Idd21.1 and Idd21.2 With IDDM6 (Human) and Iddm3 (Rat)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

"Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

NOD x 129.H2(g7) backcross delineates 129S1/SvImJ-derived genomic regions modulating type 1 diabetes development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Mapping of the murine type 1 diabetes locus Idd20 by genetic interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Three Loci on Mouse Chromosome 6 Influence Onset and Final Incidence of Type I Diabetes in NOD.C3H Congenic Strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Through Regulation of TCR Expression Levels, an Idd7 Region Gene(s) Interactively Contributes to the Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in Nonobese Diabetic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Prevention of diabetes in non-obese diabetic I-Ak transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

Transfer of a functional human immune system to mice with severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-010-0204-1

CD1d-Restricted NKT Cells: An Interstrain Comparison

21 January 2018

1 reference

12 December 2020

Passive transfer of flt-3L-derived dendritic cells delays diabetes development in NOD mice and associates with early production of interleukin (IL)-4 and IL-10 in the spleen of recipient mice

1 reference

12 December 2020

A deficiency in the in vivo clearance of apoptotic cells is a feature of the NOD mouse

1 reference

12 December 2020

Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial

1 reference

12 December 2020

Defective CD8+ T Cell Peripheral Tolerance in Nonobese Diabetic Mice

1 reference

12 December 2020

Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat

1 reference

12 December 2020

Subcongenic analysis of the Idd13 locus in NOD/Lt mice: evidence for several susceptibility genes including a possible diabetogenic role for beta 2-microglobulin.

1 reference

12 December 2020

Fine-mapping of the mouse T lymphocyte fraction (Tlf) locus on chromosome 9: association with autoimmune diabetes.

1 reference

12 December 2020

Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice

1 reference

12 December 2020

Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesis in NOD mice

1 reference

12 December 2020

Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice

1 reference

12 December 2020

Autologous mixed lymphocyte reaction in man: XV. Cellular and molecular basis of deficient autologous mixed lymphocyte response in insulin-dependent diabetes mellitus

1 reference

12 December 2020

Cytokine profile and insulin antibody IgG subclasses in patients with recent onset Type 1 diabetes treated with oral insulin

1 reference

12 December 2020

C57BL/6 and C57BL/10 inbred mouse strains differ at multiple loci on chromosome 4

1 reference

12 December 2020

Congenic Analysis of the NKT Cell Control Gene Nkt2 Implicates the Peroxisomal Protein Pxmp4

1 reference

12 December 2020

Immunostimulation circumvents diabetes in NOD/Lt mice

1 reference

12 December 2020

Defective autologous mixed leukocyte reaction in newly diagnosed type 1 diabetes mellitus

1 reference

12 December 2020

Mapping by Genetic Interaction: High-Resolution Congenic Mapping of the Type 1 Diabetes Loci Idd10 and Idd18 in the NOD Mouse

1 reference

12 December 2020

CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes

1 reference

12 December 2020

Specific deficiency of p56lck expression in T lymphocytes from type 1 diabetic patients

1 reference

12 December 2020

Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune nonobese diabetic mice. Evidence for thymic T cell anergy that correlates with the onset of insulitis

1 reference

12 December 2020

Subcongenic analysis of genetic basis for impaired development of invariant NKT cells in NOD mice

1 reference

12 December 2020

Immunological efficacy of heat shock protein 60 peptide DiaPep277 therapy in clinical type I diabetes

1 reference

12 December 2020

A defect in bone marrow derived dendritic cell maturation in the nonobesediabetic mouse

1 reference

12 December 2020

Ligand-dependent induction of noninflammatory dendritic cells by anergic invariant NKT cells minimizes autoimmune inflammation

1 reference

12 December 2020

Interactions between Idd5.1/Ctla4 and other type 1 diabetes genes

1 reference

12 December 2020

HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes

1 reference

12 December 2020

Peripheral deletion of mature CD8+ antigen-specific T cells after in vivo exposure to male antigen

1 reference

12 December 2020

Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in islet-allografted NOD/L

1 reference

12 December 2020

I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice

1 reference

12 December 2020

The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

1 reference

12 December 2020

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

1 reference

12 December 2020

Oral insulin therapy to prevent progression of immune-mediated (type 1) diabetes

1 reference

12 December 2020

Three recessive loci required for insulin-dependent diabetes in nonobese diabetic mice

1 reference

12 December 2020

Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice

1 reference

12 December 2020

Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells

1 reference

12 December 2020

Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice

1 reference

12 December 2020

Impaired activation of islet-reactive CD4 T cells in pancreatic lymph nodes of B cell-deficient nonobese diabetic mice

1 reference

12 December 2020

Defective T cell receptor/CD3 complex signaling in human type I diabetes

1 reference

12 December 2020

A Molecular Basis for MHC Class II—Associated Autoimmunity

1 reference

12 December 2020

Impact of protective IL-2 allelic variants on CD4+ Foxp3+ regulatory T cell function in situ and resistance to autoimmune diabetes in NOD mice

1 reference

12 December 2020

Identification of a Structurally Distinct CD101 Molecule Encoded in the 950-kb Idd10 Region of NOD Mice

1 reference

12 December 2020

A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus

1 reference

12 December 2020

Activation-driven T cell death. II. Quantitative differences alone distinguish stimuli triggering nontransformed T cell proliferation or death

1 reference

12 December 2020

Altered dendritic cells (DC) might be responsible for regulatory T cell imbalance and autoimmunity in nonobese diabetic (NOD) mice

1 reference

12 December 2020

Two mechanisms of antigen-specific apoptosis of myelin basic protein (MBP)-specific T lymphocytes derived from multiple sclerosis patients and normal individuals

1 reference

12 December 2020

Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats

1 reference

12 December 2020

Persistent T cell anergy in human type 1 diabetes.

1 reference

12 December 2020

Recruitment and activation of naive T cells in the islets by lymphotoxin beta receptor-dependent tertiary lymphoid structure

1 reference

12 December 2020

Investigation of the role of B-cells in type 1 diabetes in the NOD mouse

1 reference

12 December 2020

Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced

1 reference

12 December 2020

Development and function of diabetogenic T-cells in B-cell-deficient nonobese diabetic mice

1 reference

12 December 2020

Genetic Control of NKT Cell Numbers Maps to Major Diabetes and Lupus Loci

1 reference

12 December 2020

Slamf1, the NKT cell control gene Nkt1

1 reference

12 December 2020

Defective expression of the apoptosis-inducing CD95 (Fas/APO-1) molecule on T and B cells in IDDM

1 reference

12 December 2020

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice

1 reference

12 December 2020

Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice.

1 reference

12 December 2020

The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells

1 reference

12 December 2020

Positive and negative thymocyte selection induced by different concentrations of a single peptide

1 reference

12 December 2020

Development of insulitis and diabetes in B cell-deficient NOD mice

1 reference

12 December 2020

Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim.

1 reference

12 December 2020

Defective central tolerance induction in NOD mice: genomics and genetics

1 reference

12 December 2020

A susceptibility allele from a non-diabetes-prone mouse strain accelerates diabetes in NOD congenic mice

1 reference

12 December 2020

Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent

1 reference

12 December 2020

B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice.

1 reference

12 December 2020

Mechanisms of PDL1-mediated regulation of autoimmune diabetes

1 reference

12 December 2020

CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice

1 reference

12 December 2020

Crosses of NOD mice with the related NON strain. A polygenic model for IDDM

1 reference

12 December 2020

T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis

1 reference

12 December 2020

Development of diabetogenic T cells from NOD/Lt marrow is blocked when an allo-H-2 haplotype is expressed on cells of hemopoietic origin, but not on thymic epithelium

1 reference

12 December 2020

Genetic analysis of resistance to Type-1 Diabetes in ALR/Lt mice, a NOD-related strain with defenses against autoimmune-mediated diabetogenic stress

1 reference

12 December 2020

The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors

1 reference

12 December 2020

Enhanced early expansion and maturation of semi-invariant NK T cells inhibited autoimmune pathogenesis in congenic nonobese diabetic mice

1 reference

12 December 2020

Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes

1 reference

12 December 2020

B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice

1 reference

12 December 2020

Early and quantal (by litter) expression of insulin autoantibodies in the nonobese diabetic mice predict early diabetes onset

1 reference

12 December 2020

Improved engraftment of human cord blood stem cells in NOD/LtSz-scid/scid mice after irradiation or multiple-day injections into unirradiated recipients

1 reference

12 December 2020

IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function

1 reference

12 December 2020

Mapping non-class II H2-linked loci for type 1 diabetes in nonobese diabetic mice

1 reference

12 December 2020

B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice.

1 reference

12 December 2020

The enlarged population of marginal zone/CD1d(high) B lymphocytes in nonobese diabetic mice maps to diabetes susceptibility region Idd11

1 reference

12 December 2020

Genetic control of diabetogenesis in NOD/Lt mice. Development and analysis of congenic stocks.

1 reference

12 December 2020

The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

1 reference

12 December 2020

Interleukin 2 and soluble interleukin 2-receptor secretion defect in vitro in newly diagnosed type I diabetic patients

1 reference

12 December 2020

Phenotypic and Functional Characteristics of BM-Derived DC from NOD and Non-Diabetes-Prone Strains

1 reference

12 December 2020

Phenotype and function of human hematopoietic cells engrafting immune-deficient CB17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells

1 reference

12 December 2020

Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1

1 reference

12 December 2020

Localization of Idd11 using NOD congenic mouse strains: elimination of Slc9a1 as a candidate gene.

1 reference

12 December 2020

Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy

1 reference

12 December 2020

B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice

1 reference

12 December 2020

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

1 reference

12 December 2020

Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development

1 reference

12 December 2020

Defective activation of T suppressor cell function in nonobese diabetic mice. Potential relation to cytokine deficiencies

1 reference

12 December 2020

DIFFERENTIAL GLYCOSYLATION OF INTERLEUKIN 2, THE MOLECULAR BASIS FOR THE NOD Idd3 TYPE 1 DIABETES GENE?

1 reference

12 December 2020

10.1007/S00281-010-0204-1

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20424843