(Q53929277)

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Deficient activation and resistance to activation-induced apoptosis of CD8+ T cells is associated with defective peripheral tolerance in nonobese diabetic mice.

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1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

Deficient activation and resistance to activation-induced apoptosis of CD8+ T cells is associated with defective peripheral tolerance in nonobese diabetic mice. (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

author name string

Guillermo Arreaza

1

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

Konstantin Salojin

2

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

Wen Yang

3

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

Jian Zhang

4

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

Bruce Gill

5

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

Qing-Sheng Mi

6

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

Jian-Xin Gao

7

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

Craig Meagher

8

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

Mark Cameron

9

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

Terry L Delovitch

10

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

publication date

1 May 2003

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

Clinical Immunology

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

107

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

2

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

103-115

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

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The role of Fas in autoimmune diabetes

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Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

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CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

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Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement

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7 January 2021

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The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus

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7 January 2021

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Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions

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7 January 2021

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Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

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7 January 2021

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Defective CD8+ T Cell Peripheral Tolerance in Nonobese Diabetic Mice

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7 January 2021

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Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

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7 January 2021

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Peripheral selection of the T cell repertoire

1 reference

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7 January 2021

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Role of Fas-mediated cell death in the regulation of immune responses

1 reference

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7 January 2021

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Apoptosis signaling in lymphocytes.

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7 January 2021

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The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.

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7 January 2021

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Apoptotic and effector pathways in autoimmunity

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7 January 2021

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Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

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7 January 2021

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Apoptosis and the pathogenesis of IDDM: a question of life and death

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7 January 2021

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A defect in central tolerance in NOD mice

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7 January 2021

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Identification and mapping to chromosome 1 of a susceptibility locus for periinsulitis in non-obese diabetic mice

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7 January 2021

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Resistance of T-cells to apoptosis in autoimmune diabetic (NOD) mice is increased early in life and is associated with dysregulated expression of Bcl-x.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6616%2803%2900049-4

7 January 2021

based on heuristic

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Non-obese diabetic (NOD) mice display enhanced immune responses and prolonged survival of lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6616%2803%2900049-4

7 January 2021

based on heuristic

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Apoptosis resistance of nonobese diabetic peripheral lymphocytes linked to the Idd5 diabetes susceptibility region

1 reference

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7 January 2021

based on heuristic

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Defective expression of the apoptosis-inducing CD95 (Fas/APO-1) molecule on T and B cells in IDDM

1 reference

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7 January 2021

based on heuristic

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Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

1 reference

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7 January 2021

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Neonatal activation of CD28 signaling overcomes T cell anergy and prevents autoimmune diabetes by an IL-4-dependent mechanism.

1 reference

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7 January 2021

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Impaired plasma membrane targeting of Grb2-murine son of sevenless (mSOS) complex and differential activation of the Fyn-T cell receptor (TCR)-zeta-Cbl pathway mediate T cell hyporesponsiveness in autoimmune nonobese diabetic mice

1 reference

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7 January 2021

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Independent genetic regulation of T-cell and antigen-presenting cell participation in autoimmune islet inflammation

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Thymic T cell anergy in autoimmune nonobese diabetic mice is mediated by deficient T cell receptor regulation of the pathway of p21ras activation

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CD28 co-stimulation restores T cell responsiveness in NOD mice by overcoming deficiencies in Rac-1/p38 mitogen-activated protein kinase signaling and IL-2 and IL-4 gene transcription

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7 January 2021

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Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

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Portrait of an executioner: the molecular mechanism of FAS/APO-1-induced apoptosis

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T-cell anergy and altered T-cell receptor signaling: effects on autoimmune disease

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Increased nonobese diabetic Th1:Th2 (IFN-gamma:IL-4) ratio is CD4+ T cell intrinsic and independent of APC genetic background

1 reference

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7 January 2021

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The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance

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7 January 2021

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Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

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Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response

1 reference

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Impaired CD4 T cell activation due to reliance upon B cell-mediated costimulation in nonobese diabetic (NOD) mice.

1 reference

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Increased entry into the IFN-gamma effector pathway by CD4+ T cells selected by I-Ag7 on a nonobese diabetic versus C57BL/6 genetic background

1 reference

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Induction of apoptosis in mature T cells by tumour necrosis factor

1 reference

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7 January 2021

based on heuristic

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The dual functions of fas ligand in the regulation of peripheral CD8+ and CD4+ T cells

1 reference

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based on heuristic

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TNF receptor 2-deficient CD8 T cells are resistant to Fas/Fas ligand-induced cell death

1 reference

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1 reference

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The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1 reference

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Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses.

1 reference

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Cytokine-induced survival of activated T cells in vitro and in vivo

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based on heuristic

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Il-4 influences apoptosis of mycobacterium-reactive lymphocytes in the presence of TNF-alpha.

1 reference

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1 reference

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1 reference

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The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis

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1 reference

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based on heuristic

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Overexpression of the apoptosis inhibitor FLIP in T cells correlates with disease activity in multiple sclerosis.

1 reference

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Increased cellular expression of the caspase inhibitor FLIP in intrathecal lymphocytes from patients with multiple sclerosis

1 reference

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7 January 2021

based on heuristic

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Inhibition of death receptor signals by cellular FLIP

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based on heuristic

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Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

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based on heuristic

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NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans.

1 reference

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Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice

1 reference

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7 January 2021

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inferred from DOI database lookup

Identifiers

10.1016/S1521-6616(03)00049-4

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/12763479

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