Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q37740310)
Watch
English
Antimetastatic activities of heparins and modified heparins. Experimental evidence.
scientific article published on April 2010
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20434009
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20434009%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
review article
1 reference
stated in
Europe PubMed Central
title
Antimetastatic activities of heparins and modified heparins. Experimental evidence
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20434009
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20434009%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
author
Lubor Borsig
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20434009
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20434009%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
author name string
Lubor Borsig
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20434009
retrieved
22 August 2017
publication date
1 April 2010
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20434009
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20434009%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
published in
Thrombosis Research
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20434009
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20434009%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
volume
125 Suppl 2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20434009
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20434009%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
page(s)
S66-71
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20434009
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20434009%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
cites work
Molecular basis for the relationship between thrombosis and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heparin in tumor progression and metastatic dissemination.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heparin as an anticancer therapeutic
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A meta-analysis and systematic review of the efficacy and safety of anticoagulants as cancer treatment: impact on survival and bleeding complications.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of anticoagulants on cancer risk and survival: systematic review
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of heparin induced anti-cancer activity in experimental cancer models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel drug development opportunities for heparin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular diversity of heparan sulfate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of heparanase activity and tumor metastasis by laminarin sulfate and synthetic phosphorothioate oligodeoxynucleotides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-selectin- and heparanase-dependent antimetastatic activity of non-anticoagulant heparins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of experimental lung metastases of Lewis lung carcinoma cells by chemically modified heparin with reduced anticoagulant activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The attenuation of experimental lung metastasis by a bile acid acylated-heparin derivative
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduction of metastasis in a murine mammary tumour model by heparin and polyinosinic-polycytidylic acid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of metastatic cell lines derived from a murine mammary tumour, and reduction of metastasis by heparin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemical modifications of heparin that diminish its anticoagulant but preserve its heparanase-inhibitory, angiostatic, anti-tumor and anti-metastatic properties
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of B16-BL6 melanoma lung colonies by semisynthetic sulfaminoheparosan sulfates from E. coli K5 polysaccharide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Periodate-treated, non-anticoagulant heparin-carrying polystyrene (NAC-HCPS) affects angiogenesis and inhibits subcutaneous induced tumour growth and metastasis to the lung
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antimetastatic effect of tinzaparin, a low-molecular-weight heparin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endothelial P-selectin as a target of heparin action in experimental melanoma lung metastasis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential metastasis inhibition by clinically relevant levels of heparins--correlation with selectin inhibition, not antithrombotic activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective antimetastatic effect of heparins in preclinical human melanoma models is based on inhibition of migration and microvascular arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ability of different forms of heparins to suppress P-selectin function in vitro correlates to their inhibitory capacity on bloodborne metastasis in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of CXCR4-mediated breast cancer metastasis: a potential role for heparinoids?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antimetastatic effect of an orally active heparin derivative on experimentally induced metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of osteolytic bone metastasis by unfractionated heparin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of anticoagulants on tumor development of mouse cancer cell lines B16, K1735 and CT26 in lung
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term thrombin inhibition promotes cancer cell extravasation in a mouse model of experimental metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modified heparins inhibit integrin alpha(IIb)beta(3) mediated adhesion of melanoma cells to platelets in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor metastasis: mechanistic insights and clinical challenges
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer metastasis: building a framework
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heparin inhibition of selectin-mediated interactions during the hematogenous phase of carcinoma metastasis: rationale for clinical studies in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of endogenous thrombin in tumor implantation, seeding, and spontaneous metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heparanase, heparin and the coagulation system in cancer progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of tissue factor pathway inhibitor in tumor growth and metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-cancer properties of low-molecular-weight heparin: preclinical evidence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemically modified heparins as inhibitors of heparan sulfate specific endo-beta-glucuronidase (heparanase) of metastatic melanoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heparanase promotes the spontaneous metastasis of myeloma cells to bone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Syndecan-1: a dynamic regulator of the myeloma microenvironment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Platelets and cancer metastasis: a causal relationship?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-selectin deficiency attenuates tumor growth and metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Redirection of tumor metastasis by expression of E-selectin in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Carbohydrate-mediated cell adhesion involved in hematogenous metastasis of cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunohistochemical expression of the sialyl Lewis x antigen on gastric cancer cells correlates with the presence of liver metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of carbohydrate antigen sialyl Lewis(x) in colorectal cancer metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
alpha-2,3-Sialyltransferase type 3N and alpha-1,3-fucosyltransferase type VII are related to sialyl Lewis(x) synthesis and patient survival from lung carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sialyl-Lewis-X, Gleason grade and stage in non-metastatic human prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heparin attenuates metastasis mainly due to inhibition of P- and L-selectin, but non-anticoagulant heparins can have additional effects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0049-3848%2810%2970017-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0049-3848(10)70017-7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20434009
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20434009%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PubMed publication ID
20434009
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20434009
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20434009%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit