(Q37741802)

22 August 2017

1 reference

title

Genetics of SLE: evidence from mouse models (English)

1 reference

22 August 2017

Laurence Morel

1

1 reference

PubMed ID

20440287

22 August 2017

language of work or name

English

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publication date

4 May 2010

1 reference

Nature Reviews Rheumatology

22 August 2017

1 reference

22 August 2017

6

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22 August 2017

348-357

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22 August 2017

6

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https://scigraph.springernature.com/pub.10.1038/nrrheum.2010.63

22 August 2017

0 references

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Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production

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Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus

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Regulation of B cell tolerance by the lupus susceptibility gene Ly108.

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Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein

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Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c

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Murine lupus susceptibility locus Sle1a controls regulatory T cell number and function through multiple mechanisms

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Selective dysregulation of the FcgammaIIB receptor on memory B cells in SLE

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31 March 2020

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31 March 2020

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A Tlr7 translocation accelerates systemic autoimmunity in murine lupus

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

31 March 2020

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Polymorphisms of the interleukin-4 gene in chinese patients with systemic lupus erythematosus in Taiwan

31 March 2020

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A regulatory SNP at position -899 in CDKN1A is associated with systemic lupus erythematosus and lupus nephritis.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Review of recent genome-wide association scans in lupus

31 March 2020

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Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

The MHC haplotype H2b converts two pure nonlupus mouse strains to producers of antinuclear antibodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Dissection of the role of MHC class II A and E genes in autoimmune susceptibility in murine lupus models with intragenic recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

STAT4 deficiency reduces autoantibody production and glomerulonephritis in a mouse model of lupus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

STAT4: genetics, mechanisms, and implications for autoimmunity

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoimmune background.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Protein tyrosine phosphatases in autoimmunity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

IRAK1: a critical signaling mediator of innate immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

IL-10 regulates murine lupus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Interleukin-10 and the interleukin-10 receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Critical requirement of CD11b (Mac-1) on T cells and accessory cells for development of experimental autoimmune encephalomyelitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

The integrin Mac-1 (CR3) mediates internalization and directs Bacillus anthracis spores into professional phagocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Murine dendritic cell type I IFN production induced by human IgG-RNA immune complexes is IFN regulatory factor (IRF)5 and IRF7 dependent and is required for IL-6 production

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Pituitary tumor transforming gene interacts with Sp1 to modulate G1/S cell phase transition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Enhancing immunity through autophagy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

The role of TNF superfamily members in T-cell function and diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

ABINs: A20 binding inhibitors of NF-kappa B and apoptosis signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

BANK negatively regulates Akt activation and subsequent B cell responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Regulation and functions of Blimp-1 in T and B lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Fcgamma receptors as regulators of immune responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Recent insights into the genetic basis of systemic lupus erythematosus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Accelerated autoimmunity and lupus nephritis in NZB mice with an engineered heterozygous deficiency in tumor necrosis factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

HLA-DR modulates autoantibody repertoire, but not mortality, in a humanized mouse model of systemic lupus erythematosus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Renaissance for mouse models of human hematopoiesis and immunobiology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Logic and extent of miRNA-mediated control of autoimmune gene expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Sle3 and Sle5 can independently couple with Sle1 to mediate severe lupus nephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Epistatic suppression of systemic lupus erythematosus: fine mapping of Sles1 to less than 1 mb

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Fcγ receptor-dependent expansion of a hyperactive monocyte subset in lupus-prone mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

A lupus-susceptibility C57BL/6 locus on chromosome 3 (Sle18) contributes to autoantibody production in 129 mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Lupus susceptibility genes may breach tolerance to DNA by impairing receptor editing of nuclear antigen-reactive B cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Genetic dissection of the murine lupus susceptibility locus Sle2: contributions to increased peritoneal B-1a cells and lupus nephritis map to different loci

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Deficiency of type I interferon contributes to Sle2-associated component lupus phenotypes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Dissociation of the genetic loci leading to b1a and NKT cell expansions from autoantibody production and renal disease in B6 mice with an introgressed New Zealand Black chromosome 4 interval

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Autoimmune alterations induced by the New Zealand Black Lbw2 locus in BWF1 mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Differential role of three major New Zealand Black-derived loci linked with Yaa-induced murine lupus nephritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Characterization of reciprocal Lmb1-4 interval MRL-Faslpr and C57BL/6-Faslpr congenic mice reveals significant effects from Lmb3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

A lupus-suppressor BALB/c locus restricts IgG2 autoantibodies without altering intrinsic B cell-tolerance mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

Selective up-regulation of intact, but not defective env RNAs of endogenous modified polytropic retrovirus by the Sgp3 locus of lupus-prone mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

ENU-mutagenesis: insight into immune function and pathology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.63

The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes

31 March 2020

1 reference

12 December 2020

The nature and identification of quantitative trait loci: a community's view

1 reference

12 December 2020

Murine lupus susceptibility locus Sle1a requires the expression of two sub-loci to induce inflammatory T cells

1 reference

12 December 2020

Autoimmune glomerulonephritis induced in congenic mouse strain carrying telomeric region of chromosome 1 derived from MRL/MpJ.

1 reference

12 December 2020

Genetic dissection of Sle pathogenesis: Sle3 on murine chromosome 7 impacts T cell activation, differentiation, and cell death

1 reference

12 December 2020

Murine models of systemic lupus erythematosus

1 reference

12 December 2020

Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes

1 reference

12 December 2020

Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2010.63

1 reference

PubMed ID

20440287

Dimensions Publication ID

22 August 2017

0 references

1 reference

PubMed ID

20440287