(Q37744992)

22 August 2017

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title

Electroporation for DNA immunization: clinical application (English)

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Sylvia van Drunen Littel-van den Hurk

22 August 2017

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series ordinal

1

object named as

Sylvia van Drunen Littel-van den Hurk

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22 August 2017

D Hannaman

2

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22 August 2017

1 May 2010

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Expert Review of Vaccines

22 August 2017

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22 August 2017

9

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22 August 2017

5

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22 August 2017

503-517

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Design of PCR-amplified DNA fragments for in vivo gene delivery: size-dependency on stability and transgene expression

22 August 2017

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Immunization with plasmid DNA encoding for the measles virus hemagglutinin and nucleoprotein leads to humoral and cell-mediated immunity

21 January 2018

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Introduction: gene vaccination, current concepts and future directions

21 January 2018

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DNA-mediated immunization to hepatitis B surface antigen: longevity of primary response and effect of boost.

21 January 2018

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Immune responses following neonatal DNA vaccination are long-lived, abundant, and qualitatively similar to those induced by conventional immunization

21 January 2018

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Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers

21 January 2018

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First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response

21 January 2018

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Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice

21 January 2018

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Gene vaccination with naked plasmid DNA: mechanism of CTL priming

21 January 2018

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Immunobiology of dendritic cells

21 January 2018

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DNA vaccines: ready for prime time?

21 January 2018

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21 January 2018

West Nile virus vaccines

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Electroporation-based DNA immunisation: translation to the clinic

21 January 2018

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DNA vaccines: are they still just a powerful tool for the future?

21 January 2018

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Fetal immunization by a DNA vaccine delivered into the oral cavity

21 January 2018

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Topical administration of HSV gD-IL-2 DNA is highly protective against murine herpetic stromal keratitis.

21 January 2018

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Suppository-mediated DNA immunization induces mucosal immunity against bovine herpesvirus-1 in cattle

21 January 2018

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Gene gun-mediated DNA immunization primes development of mucosal immunity against bovine herpesvirus 1 in cattle

21 January 2018

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Protective DNA immunization against Chlamydia pneumoniae

21 January 2018

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Phase I study of intranodal delivery of a plasmid DNA vaccine for patients with Stage IV melanoma

21 January 2018

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Effects of high electric fields on micro-organisms. 3. Lysis of erythrocytes and protoplasts

21 January 2018

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Electrical Breakdown of Bimolecular Lipid Membranes as an Electromechanical Instability

21 January 2018

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Electrical hemolysis of human and bovine red blood cells

21 January 2018

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Hemolysis of human erythrocytes by transient electric field

21 January 2018

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Formation and resealing of pores of controlled sizes in human erythrocyte membrane

21 January 2018

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What is (still not) known of the mechanism by which electroporation mediates gene transfer and expression in cells and tissues

21 January 2018

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Optimization of electroporation for transfection of mammalian cell lines

21 January 2018

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Fundamentals of electroporative delivery of drugs and genes

21 January 2018

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Electrophoretic component of electric pulses determines the efficacy of in vivo DNA electrotransfer.

21 January 2018

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Electroporation in biology: methods, applications, and instrumentation

21 January 2018

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Electroporation of cell membranes

21 January 2018

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Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy

21 January 2018

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Optimal Electric Conditions in Electrical Impulse Chemotherapy

21 January 2018

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Transient electropermeabilization of cells in culture. Increase of the cytotoxicity of anticancer drugs

21 January 2018

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Bleomycin-mediated electrochemotherapy of basal cell carcinoma

21 January 2018

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In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA

21 January 2018

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Strategies for improved formulation and delivery of DNA vaccines to veterinary target species

21 January 2018

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Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens

21 January 2018

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Enhancement of DNA vaccine potency in rhesus macaques by electroporation

21 January 2018

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Electric pulse-mediated gene delivery to various animal tissues

21 January 2018

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Theory and in vivo application of electroporative gene delivery

21 January 2018

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Gene transfer into muscle by electroporation in vivo.

21 January 2018

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Long-term, high level in vivo gene expression after electric pulse-mediated gene transfer into skeletal muscle.

21 January 2018

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Electropermeabilization of skeletal muscle enhances gene transfer in vivo

21 January 2018

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Efficient nonviral cutaneous transfection

21 January 2018

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Cutaneous transfection and immune responses to intradermal nucleic acid vaccination are significantly enhanced by in vivo electropermeabilization

21 January 2018

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Technical and regulatory hurdles for DNA vaccines

21 January 2018

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Gene-based vaccines: recent technical and clinical advances

21 January 2018

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Increased gene expression and inflammatory cell infiltration caused by electroporation are both important for improving the efficacy of DNA vaccines

21 January 2018

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Electroporation-facilitated delivery of plasmid DNA in skeletal muscle: plasmid dependence of muscle damage and effect of poloxamer 188.

21 January 2018

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Recruitment of antigen-presenting cells to the site of inoculation and augmentation of human immunodeficiency virus type 1 DNA vaccine immunogenicity by in vivo electroporation

21 January 2018

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Enhancement of cellular immune response to a prostate cancer DNA vaccine by intradermal electroporation

21 January 2018

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Skin electroporation: effects on transgene expression, DNA persistence and local tissue environment

21 January 2018

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Optimization of skin electroporation in mice to increase tolerability of DNA vaccine delivery to patients

21 January 2018

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Persistent immune responses induced by a human immunodeficiency virus DNA vaccine delivered in association with electroporation in the skin of nonhuman primates

21 January 2018

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Enhancement of immune responses to an HBV DNA vaccine by electroporation

21 January 2018

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Immunogenicity in mice and rabbits of DNA vaccines expressing woodchuck hepatitis virus antigens

21 January 2018

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The relative immunogenicity of DNA vaccines delivered by the intramuscular needle injection, electroporation and gene gun methods

21 January 2018

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Enhanced in vivo transgene expression and immunogenicity from plasmid vectors following electrostimulation in rodents and primates.

21 January 2018

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A novel electroporation device for gene delivery in large animals and humans.

21 January 2018

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Effect of plasmid DNA vaccine design and in vivo electroporation on the resulting vaccine-specific immune responses in rhesus macaques

21 January 2018

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Increased immune responses in rhesus macaques by DNA vaccination combined with electroporation

21 January 2018

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Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques

21 January 2018

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DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge

21 January 2018

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High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model

21 January 2018

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Modulation of the immune response induced by gene electrotransfer of a hepatitis C virus DNA vaccine in nonhuman primates

21 January 2018

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Comparative performance of a licensed anthrax vaccine versus electroporation based delivery of a PA encoding DNA vaccine in rhesus macaques

21 January 2018

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Parameters for DNA vaccination using adaptive constant-current electroporation in mouse and pig models.

21 January 2018

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In vivo electroporation improves immune responses to DNA vaccination in sheep

21 January 2018

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Co-delivery of plasmid-encoded cytokines modulates the immune response to a DNA vaccine delivered by in vivo electroporation.

21 January 2018

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A single DNA immunization in combination with electroporation prolongs the primary immune response and maintains immune memory for six months

21 January 2018

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DNA injection in combination with electroporation: a novel method for vaccination of farmed ruminants.

21 January 2018

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Immune-enhancing effects of growth hormone-releasing hormone delivered by plasmid injection and electroporation.

21 January 2018

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Effects of plasmid-mediated growth hormone releasing hormone supplementation in young, healthy Beagle dogs

21 January 2018

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Gene therapy for the treatment of hemophilia B using PINC-formulated plasmid delivered to muscle with electroporation

21 January 2018

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Gene therapy by electroporation for the treatment of chronic renal failure in companion animals

21 January 2018

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Comparative immunogenicity of trivalent influenza vaccine administered by intradermal or intramuscular route in healthy adults

21 January 2018

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Electroporation of synthetic DNA antigens offers protection in nonhuman primates challenged with highly pathogenic avian influenza virus

21 January 2018

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Preclinical and clinical safety studies on DNA vaccines

21 January 2018

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Efficient and regulated erythropoietin production by naked DNA injection and muscle electroporation

21 January 2018

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FVIII gene delivery by muscle electroporation corrects murine hemophilia A.

21 January 2018

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Optimizing plasmid-based gene transfer for investigating skeletal muscle structure and function

21 January 2018

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Tolerability of two sequential electroporation treatments using MedPulser DNA delivery system (DDS) in healthy adults.

21 January 2018

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In vivo electroporation enhances the immunogenicity of hepatitis C virus nonstructural 3/4A DNA by increased local DNA uptake, protein expression, inflammation, and infiltration of CD3+ T cells

21 January 2018

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Plasmid DNA malaria vaccine: the potential for genomic integration after intramuscular injection

21 January 2018

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Potential DNA vaccine integration into host cell genome

21 January 2018

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Biodistribution of DNA Plasmid Vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile Virus Is Similar, without Integration, despite Differing Plasmid Backbones or Gene Inserts

21 January 2018

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Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation

21 January 2018

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DNA vaccination with electroporation induces increased antibody responses in patients with prostate cancer

21 January 2018

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DNA vaccine therapy for chronic hepatitis C virus (HCV) infection: immune control of a moving target.

21 January 2018

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Electroporation for the delivery of DNA-based vaccines and immunotherapeutics: current clinical developments

21 January 2018

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DNA vaccination protects against an influenza challenge in a double-blind randomised placebo-controlled phase 1b clinical trial

21 January 2018

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TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

21 January 2018

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In vivo gene electroinjection and expression in rat liver

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERV.10.42

1 reference

22 August 2017

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PubMed ID

20450325