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English
Yorkie: the final destination of Hippo signaling.
scientific article published on 07 May 2010
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Europe PubMed Central
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2919348
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2 February 2020
review article
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title
Yorkie: the final destination of Hippo signaling
(English)
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Europe PubMed Central
PMCID
2919348
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20452772%20AND%20SRC:MED&resulttype=core&format=json
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2 February 2020
author
Kenneth D. Irvine
series ordinal
2
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Europe PubMed Central
PMCID
2919348
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20452772%20AND%20SRC:MED&resulttype=core&format=json
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2 February 2020
author name string
Hyangyee Oh
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1
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Europe PubMed Central
PMCID
2919348
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20452772%20AND%20SRC:MED&resulttype=core&format=json
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2 February 2020
publication date
7 May 2010
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Europe PubMed Central
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2919348
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2 February 2020
published in
Trends in Cell Biology
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2 February 2020
volume
20
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Europe PubMed Central
PMCID
2919348
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2 February 2020
page(s)
410-417
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Europe PubMed Central
PMCID
2919348
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20452772%20AND%20SRC:MED&resulttype=core&format=json
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2 February 2020
issue
7
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Europe PubMed Central
PMCID
2919348
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2 February 2020
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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
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WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus
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22 August 2017
salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
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Transcriptional output of the Salvador/warts/hippo pathway is controlled in distinct fashions in Drosophila melanogaster and mammalian cell lines
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Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown.
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14 September 2017
The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie
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14 September 2017
YAP regulates neural progenitor cell number via the TEA domain transcription factor
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14 September 2017
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control
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14 September 2017
Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways
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14 September 2017
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms
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23 June 2018
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
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23 June 2018
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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23 June 2018
The scalloped gene encodes a novel, evolutionarily conserved transcription factor required for sensory organ differentiation in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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23 June 2018
Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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1 September 2018
Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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1 September 2018
Nuclear localization and pro-apoptotic signaling of YAP2 require intact PDZ-binding motif.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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1 September 2018
Phosphoproteome analysis of Drosophila melanogaster embryos
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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1 September 2018
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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1 September 2018
The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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1 September 2018
Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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1 September 2018
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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1 September 2018
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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1 September 2018
The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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1 September 2018
TGF-beta signaling, Smads, and tumor suppressors.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919348
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1 September 2018
Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20452772
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Roles for scalloped and vestigial in regulating cell affinity and interactions between the wing blade and the wing hinge
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20452772
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The human tumour suppressor LATS1 is activated by human MOB1 at the membrane
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20452772
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.TCB.2010.04.005
1 reference
stated in
Europe PubMed Central
PMCID
2919348
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20452772%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
PMCID
2919348
1 reference
stated in
Europe PubMed Central
PMCID
2919348
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20452772%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
PubMed ID
20452772
1 reference
stated in
Europe PubMed Central
PMCID
2919348
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20452772%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
ResearchGate publication ID
44582850
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