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NOTCH1 PEST domain mutants stimulate HEY transcription
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2220981)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
part of
Constitutive Signaling by NOTCH1 PEST Domain Mutants
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
exact match
https://identifiers.org/reactome:R-HSA-2220981
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
has part(s)
HEY Genes [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
HEY [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
NOTCH1 PEST Domain Mutants Coactivator Complex:HEY Genes [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
cites work
Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
Identifiers
Reactome ID
R-HSA-2220981
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220981
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