(Q37754720)

22 August 2017

title

Eicosanoids in inflammation and cancer: the role of COX-2. (English)

1 reference

22 August 2017

0 references

Smita Agarwal

1

1 reference

22 August 2017

Gorla Venkateswara Reddy

series ordinal

2

1 reference

22 August 2017

Pallu Reddanna

series ordinal

3

1 reference

22 August 2017

publication date

1 March 2009

1 reference

Expert Review of Clinical Immunology

22 August 2017

published in

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22 August 2017

volume

5

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22 August 2017

issue

2

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22 August 2017

page(s)

145-165

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Activation and regulation of cellular eicosanoid biosynthesis.

22 August 2017

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Lipoxygenase metabolism: roles in tumor progression and survival

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Prostaglandin endoperoxide synthase: structure and catalysis

21 January 2018

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21 January 2018

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Kinetic studies on the conversion of prostaglandin endoperoxide PGH2 by thromboxane synthase

21 January 2018

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Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells

21 January 2018

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Differential regulation of cyclooxygenases 1 and 2 by interleukin-1 beta, tumor necrosis factor-alpha, and transforming growth factor-beta 1 in human lung fibroblasts

21 January 2018

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Cyclo-oxygenase-2 contributes to constitutive prostanoid production in rat kidney and brain

21 January 2018

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Cellular distribution and contribution of cyclooxygenase COX-2 to diabetogenesis in NOD mouse.

21 January 2018

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Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia.

21 January 2018

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Expression of cyclooxygenase-2 in rat testis

21 January 2018

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COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression

21 January 2018

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Acetaminophen-induced hypothermia in mice is mediated by a prostaglandin endoperoxide synthase 1 gene-derived protein

21 January 2018

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COX-3 the enzyme and the concept: steps towards highly specialized pathways and precision therapeutics?

21 January 2018

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The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

21 January 2018

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Prostaglandin receptor signaling in disease.

21 January 2018

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Origin and physiological roles of inflammation

21 January 2018

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15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Endogenous receptor agonists: resolving inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Sepsis: current concepts in intracellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

The complement system in regulation of adaptive immunity

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Nitrogen oxide levels in patients after trauma and during sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cytokines, chemokines, and cell adhesion molecules in inflammatory myopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

21 January 2018

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Cellular and molecular mechanisms of fibrosis

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Points of control in inflammation

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Resolution of inflammation: the beginning programs the end

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

The role of complement in the development of systemic lupus erythematosus

21 January 2018

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Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide.

21 January 2018

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Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2.

21 January 2018

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COX-2 in inflammation and resolution

21 January 2018

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The Role of Arachidonic Acid Oxygenation Products in Pain and Inflammation

21 January 2018

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The role of IP prostanoid receptors in inflammatory pain

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Analysis of the effects of cyclooxygenase (COX)-1 and COX-2 in spinal nociceptive transmission using indomethacin, a non-selective COX inhibitor, and NS-398, a COX-2 selective inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Thermoregulatory actions of eicosanoids in the central nervous system with particular regard to the pathogenesis of fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Sequential induction of prostaglandin E and D synthases in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Molecular circuits of resolution: formation and actions of resolvins and protectins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Inhibition of monosodium urate monohydrate crystal-induced acute inflammation by retrovirally transfected prostaglandin D synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Anti-inflammatory lipid mediators and insights into the resolution of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

1 reference

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The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

9-Deoxy-delta 9, delta 12-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma

21 January 2018

1 reference

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Essential role for hematopoietic prostaglandin D2 synthase in the control of delayed type hypersensitivity

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

COX-2 inhibitors. Are they nonsteroidal anti-inflammatory drugs with a better safety profile?

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

The use of NSAIDs in rheumatic disorders 2005: a global perspective

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

The role of cyclooxygenases in inflammation, cancer, and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions

21 January 2018

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Gastrointestinal toxic side effects of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2-specific inhibitors

21 January 2018

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Minimizing complications from nonsteroidal antiinflammatory drugs: cost-effectiveness of competing strategies in varying risk groups

21 January 2018

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Cyclooxygenase inhibitors--current status and future prospects

21 January 2018

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Improvements with esomeprazole in patients with upper gastrointestinal symptoms taking non-steroidal antiinflammatory drugs, including selective COX-2 inhibitors

21 January 2018

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Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group.

21 January 2018

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Prevalence and incidence of gastroduodenal ulcers during treatment with vascular protective doses of aspirin

21 January 2018

1 reference

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Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers

21 January 2018

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Computer aided drug design approaches to develop cyclooxygenase based novel anti-inflammatory and anti-cancer drugs

21 January 2018

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A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.

21 January 2018

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Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

21 January 2018

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Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic

21 January 2018

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Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis

21 January 2018

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Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis

21 January 2018

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Pharmacological intervention of cyclooxygenase-2 and 5-lipoxygenase pathways. Impact on inflammation and cancer.

21 January 2018

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Selective inhibition of cyclooxygenase-2 (COX-2) by 1alpha,25-dihydroxy-16-ene-23-yne-vitamin D3, a less calcemic vitamin D analog

21 January 2018

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Coxibs and cardiovascular side-effects: from light to shadow.

21 January 2018

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Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population

21 January 2018

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Selective inhibition of cyclooxygenase-2 by C-phycocyanin, a biliprotein from Spirulina platensis.

21 January 2018

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Dietary cancer chemopreventive agents - targeting inflammation and Nrf2 signaling pathway

21 January 2018

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Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke.

21 January 2018

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Activity and potential role of licofelone in the management of osteoarthritis

21 January 2018

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Licofelone suppresses prostaglandin E2 formation by interference with the inducible microsomal prostaglandin E2 synthase-1.

21 January 2018

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Inflammation and cancer: back to Virchow?

21 January 2018

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Infections as a major preventable cause of human cancer

21 January 2018

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Inflammation and cancer: how hot is the link?

21 January 2018

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21 January 2018

Inflammation and cancer

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Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

21 January 2018

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Rules for making human tumor cells

21 January 2018

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Cyclooxygenases, prostanoids, and tumor progression

21 January 2018

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Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer

21 January 2018

1 reference

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Contributory role of 5-lipoxygenase and its association with angiogenesis in the promotion of inflammation-associated colonic tumorigenesis by cigarette smoking.

21 January 2018

1 reference

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Non-steroidal anti-inflammatory drugs to potentiate chemotherapy effects: from lab to clinic

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cyclooxygenase-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention

21 January 2018

1 reference

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Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade

21 January 2018

1 reference

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Cyclo-oxygenase-2 and its inhibition in cancer: is there a role?

21 January 2018

1 reference

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Induction of apoptosis by cyclo-oxygenase-2 inhibitor NS398 through a cytochrome C-dependent pathway in esophageal cancer cells

21 January 2018

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COX-2 inhibits Fas-mediated apoptosis in cholangiocarcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Lipoxygenase and cyclooxygenase metabolism: new insights in treatment and chemoprevention of pancreatic cancer

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cyclooxygenases in cancer: progress and perspective

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Host cyclooxygenase-2 modulates carcinoma growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

PGE(2) stimulates VEGF expression in endothelial cells via ERK2/JNK1 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Prostaglandins and gangliosides of tumor microenvironment: their role in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cyclooxygenase-2 as a target for anticancer drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Multi-faceted analyses of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

NSAIDs and chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Many actions of cyclooxygenase-2 in cellular dynamics and in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cyclooxygenase-2: a novel molecular target for the prevention and treatment of head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Nested case-control study of the effects of non-steroidal anti-inflammatory drugs on breast cancer risk and stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Non-steroidal anti-inflammatory drugs and bladder cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Role of BAX in the apoptotic response to anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of bax and bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Anti-proliferative and apoptotic effects of celecoxib on human chronic myeloid leukemia in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Selective inhibition of cyclooxygenase-2 inhibits colon cancer cell adhesion to extracellular matrix by decreased expression of beta1 integrin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

The sulindac derivatives OSI-461, OSIP486823, and OSIP487703 arrest colon cancer cells in mitosis by causing microtubule depolymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cyclooxygenase-2, player or spectator in cyclooxygenase-2 inhibitor-induced apoptosis in prostate cancer cells

21 January 2018

1 reference

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A novel pathway involving melanoma differentiation associated gene-7/interleukin-24 mediates nonsteroidal anti-inflammatory drug-induced apoptosis and growth arrest of cancer cells.

21 January 2018

1 reference

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The nonsteroidal anti-inflammatory drug NS398 reactivates SPARC expression via promoter demethylation to attenuate invasiveness of lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Surgically induced accelerated local and distant tumor growth is significantly attenuated by selective COX-2 inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Sequential gene expression of P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP) and lung resistance protein: functional activity of P-gp and MRP present in the doxorubicin-resistant human K562 cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

The MDR phenotype is associated with the expression of COX-2 and iNOS in a human hepatocellular carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Regulation of MDR-1 (P-glycoprotein) by cyclooxygenase-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Mitochondrial control of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

The potential role of cyclooxygenase-2 inhibitors in the treatment of experimentally-induced mammary tumour: does celecoxib enhance the anti-tumour activity of doxorubicin?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cyclooxygenase-2: potential role in regulation of drug efflux and multidrug resistance phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cyclooxygenase-independent down-regulation of multidrug resistance-associated protein-1 expression by celecoxib in human lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Imatinib-resistant K562 cells are more sensitive to celecoxib, a selective COX-2 inhibitor: role of COX-2 and MDR-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Alteration of mitochondrial membrane potential by Spirulina platensis C-phycocyanin induces apoptosis in the doxorubicinresistant human hepatocellular-carcinoma cell line HepG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Curcumin inhibits cyclooxygenase-2 transcription in bile acid- and phorbol ester-treated human gastrointestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Phase II trial of curcumin in patients with advanced pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Resveratrol and cancer: chemoprevention, apoptosis, and chemo-immunosensitizing activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Resveratrol and cancer: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Antiangiogenic properties of natural polyphenols from red wine and green tea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Targeting signal transduction pathways by chemopreventive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Anti-inflammatory activity of flavonoids from Cayaponia tayuya roots.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

A potential new treatment for rheumatoid arthritis: thunder god vine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Co-administration of C-Phycocyanin ameliorates thioacetamide-induced hepatic encephalopathy in Wistar rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

C-Phycocyanin, a selective cyclooxygenase-2 inhibitor, induces apoptosis in lipopolysaccharide-stimulated RAW 264.7 macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Molecular mechanisms in C-Phycocyanin induced apoptosis in human chronic myeloid leukemia cell line-K562.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Cyclooxygenase-2 and 5-lipoxygenase converging functions on cell proliferation and tumor angiogenesis: implications for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

COX-2/5-LOX dual acting anti-inflammatory drugs in cancer chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Inflammation by remote control

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Synthesis of 10,11-Dihydro-12-oxo-LTB4, a Key Biochemical Intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

An efficient approach to the synthesis of LTB4 and ω-substituted LTB4 metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

Role of prostaglandin-mediated vasodilatation in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.5.2.145

21 January 2018

Identifiers

DOI

10.1586/1744666X.5.2.145

1 reference

22 August 2017

1 reference