(Q37756146)

22 August 2017

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title

Blunting the knife: development of vaccines targeting digestive proteases of blood-feeding helminth parasites (English)

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22 August 2017

3

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22 August 2017

Mark S Pearson

1

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author name string

Najju Ranjit

series ordinal

2

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22 August 2017

language of work or name

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1 August 2010

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22 August 2017

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22 August 2017

volume

391

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22 August 2017

issue

8

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22 August 2017

page(s)

901-911

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Fasciola hepatica leucine aminopeptidase, a promising candidate for vaccination against ruminant fasciolosis

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites

21 January 2018

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The genome of the blood fluke Schistosoma mansoni

21 January 2018

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Cathepsin D--many functions of one aspartic protease

21 January 2018

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Proteolysis of human hemoglobin by schistosome cathepsin D.

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

Blood 'n' guts: an update on schistosome digestive peptidases

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

A distinctive repertoire of cathepsins is expressed by juvenile invasive Fasciola hepatica.

21 January 2018

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A comparative study of the spatial distribution of schistosomiasis in Mali in 1984-1989 and 2004-2006

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells

21 January 2018

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Identification of novel proteases and immunomodulators in the secretions of schistosome cercariae that facilitate host entry.

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

Fasciola hepatica cathepsin L-like proteases: biology, function, and potential in the development of first generation liver fluke vaccines

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

A multienzyme network functions in intestinal protein digestion by a platyhelminth parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

Transcriptional changes in Schistosoma mansoni during early schistosomula development and in the presence of erythrocytes

21 January 2018

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The secretome of the filarial parasite, Brugia malayi: proteomic profile of adult excretory-secretory products.

21 January 2018

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Protection against Schistosoma mansoni infection with a recombinant baculovirus-expressed subunit of calpain

21 January 2018

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Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

mRNA sequences for Haemonchus contortus intestinal cathepsin B-like cysteine proteases display an extreme in abundance and diversity compared with other adult mammalian parasitic nematodes

21 January 2018

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Vaccination against fasciolosis by a multivalent vaccine of stage-specific antigens

21 January 2018

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Identification of a serodiagnostic antigen, legumain, by immunoproteomic analysis of excretory-secretory products of Clonorchis sinensis adult worms.

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

Chapter 4. Peptidases of trematodes

21 January 2018

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Protection induced by vaccinating sheep with a thiol-binding extract of Haemonchus contortus membranes is associated with its protease components

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

Cloning and expression of the major secreted cathepsin B-like protein from juvenile Fasciola hepatica and analysis of immunogenicity following liver fluke infection.

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

Cathepsin B of Schistosoma mansoni. Purification and activation of the recombinant proenzyme secreted by Saccharomyces cerevisiae

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

Excretory/secretory proteome of the adult developmental stage of human blood fluke, Schistosoma japonicum

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Molecular cloning and characterisation of a putative aspartate proteinase associated with a gut membrane protein complex from adult Haemonchus contortus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.074

New drugs for an ancient parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Proteases in parasitic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

RNA interference of Schistosoma mansoni cathepsin D, the apical enzyme of the hemoglobin proteolysis cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Correlation of specific antibody titre and avidity with protection in cattle immunized against Fasciola hepatica.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Molecular characterization of a family of metalloendopeptidases from the intestinal brush border of Haemonchus contortus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

A survey of the intestinal transcriptomes of the hookworms, Necator americanus and Ancylostoma caninum, using tissues isolated by laser microdissection microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Protection studies in sheep using affinity-purified and recombinant cysteine proteinases of adult Haemonchus contortus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Hydrolysis of erythrocyte proteins by proteases of malaria parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Cysteine proteases of parasitic organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Induction of protective immunity against Schistosoma mansoni via DNA priming and boosting with the large subunit of calpain (Sm-p80): adjuvant effects of granulocyte-macrophage colony-stimulating factor and interleukin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Cloning and characterization of a microsomal aminopeptidase from the intestine of the nematode Haemonchus contortus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Metalloendopeptidases from the intestinal brush border of Haemonchus contortus as protective antigens for sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Aspartyl proteases from the intestinal brush border of Haemonchus contortus as protective antigens for sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Structural and Functional Relationships in the Virulence-associated Cathepsin L Proteases of the Parasitic Liver Fluke, Fasciola hepatica

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Ov-APR-1, an aspartic protease from the carcinogenic liver fluke, Opisthorchis viverrini: functional expression, immunolocalization and subsite specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Vaccine efficacy of recombinant cathepsin D aspartic protease from Schistosoma japonicum

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Digestive proteases of blood-feeding nematodes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Hookworm cathepsin D aspartic proteases: contributing roles in the host-specific degradation of serum proteins and skin macromolecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Ancylostoma caninum MTP-1, an astacin-like metalloprotease secreted by infective hookworm larvae, is involved in tissue migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

Elucidating the transcriptome of Fasciola hepatica - a key to fundamental and biotechnological discoveries for a neglected parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

The Schistosoma japonicum genome reveals features of host-parasite interplay

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.074

21 January 2018

Identifiers

DOI

10.1515/BC.2010.074

1 reference

22 August 2017

1 reference