(Q37765141)

22 August 2017

1 reference

title

Nuclease deficiencies promote end-stage lupus nephritis but not nephritogenic autoimmunity in (NZB × NZW) F1 mice (English)

1 reference

22 August 2017

1 reference

3

Ole P Rekvig

1 reference

22 August 2017

Silje Fismen

1

1 reference

22 August 2017

Elin S Mortensen

series ordinal

2

1 reference

22 August 2017

publication date

15 June 2010

1 reference

Immunology & Cell Biology

22 August 2017

published in

1 reference

22 August 2017

volume

89

1 reference

22 August 2017

issue

1

1 reference

22 August 2017

page(s)

90-99

1 reference

Progression of murine lupus nephritis is linked to acquired renal Dnase1 deficiency and not to up-regulated apoptosis

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Anti-dsDNA antibodies promote initiation, and acquired loss of renal Dnase1 promotes progression of lupus nephritis in autoimmune (NZBxNZW)F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Nucleosomes possess a high affinity for glomerular laminin and collagen IV and bind nephritogenic antibodies in murine lupus-like nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Role of nucleosomes for induction and glomerular binding of autoantibodies in lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Regulation of lupus-related autoantibody production and clinical disease by Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Matrix metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Features of systemic lupus erythematosus in Dnase1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Alpha-actinin is a cross-reactive renal target for pathogenic anti-DNA antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Glomerular targets of nephritogenic autoantibodies in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Nephritogenic potential of anti-DNA antibodies against necrotic nucleosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Lupus anti-DNA autoantibodies cross-react with a glomerular structural protein: a case for tissue injury by molecular mimicry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Glomerular binding of anti-dsDNA autoantibodies: the dispute resolved?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Impaired clearance of dying cells in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Deranged removal of apoptotic cells: its role in the genesis of lupus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Triggers for anti-chromatin autoantibody production in SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Decreased phagocytosis of apoptotic cells in diseased SLE mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

The key role of nucleosomes in lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Lupus: Key Pathogenic Mechanisms and Contributing Factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Measurement of deoxyribonuclease I (DNase) in the serum and urine of systemic lupus erythematosus (SLE)-prone NZB/NZW mice by a new radial enzyme diffusion assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Trashing the genome: the role of nucleases during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Expression pattern of the deoxyribonuclease 1 gene: lessons from the Dnase1 knockout mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Cisplatin nephrotoxicity is mediated by deoxyribonuclease I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Induction of renal endonuclease G by cisplatin is reduced in DNase I-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Genetic control of urinary deoxyribonuclease I (DNase I) activity levels in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Lupus nephritis: the central role of nucleosomes revealed

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

The classification of glomerulonephritis in systemic lupus erythematosus revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Toll-like receptor 9 dependent activation of MAPK and NF-kB is required for the CpG ODN-induced matrix metalloproteinase-9 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

The toll of too much TLR7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr) mice in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Immunity and autoimmunity induced by polyomaviruses: clinical, experimental and theoretical aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Mechanisms of transcriptional regulation of cellular genes by SV40 large T- and small T-antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Autoimmunity to DNA and nucleosomes in binary tetracycline-regulated polyomavirus T-Ag transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Anti-double-stranded DNA antibodies, nucleosomes, and systemic lupus erythematosus: a time for new paradigms?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Circulating chromatin-anti-chromatin antibody complexes bind with high affinity to dermo-epidermal structures in murine and human lupus nephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Tolerance, danger, and the extended family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Friendly and dangerous signals: is the tissue in control?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

The danger model: a renewed sense of self

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

A molecular analysis of the low serum deoxyribonuclease activity in lupus patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Nucleases in programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Apoptosis: a review of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Murine serum nucleases--contrasting effects of plasmin and heparin on the activities of DNase1 and DNase1-like 3 (DNase1l3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Identification, localization, and expression of two novel human genes similar to deoxyribonuclease I

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

cDNA cloning of human DNase gamma: chromosomal localization of its gene and enzymatic properties of recombinant protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Lack of chromatin and nuclear fragmentation in vivo impairs the production of lupus anti-nuclear antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Anti-nuclear antibody production and immune-complex glomerulonephritis in BALB/c mice treated with pristane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

DNase II: genes, enzymes and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Generation and characterization of endonuclease G null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Cellular requirements for anti-DNA production induced in mice by immunization with bacterial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Initiation of autoimmunity to self-proteins complexed with viral antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Initiation of autoimmunity to the p53 tumor suppressor protein by complexes of p53 and SV40 large T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Expression of the Epstein-Barr virus nuclear antigen-1 (EBNA-1) in the mouse can elicit the production of anti-dsDNA and anti-Sm antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Complement receptor 2 and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Autoimmune accelerating genes, lpr and Yaa, in murine systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Nrf2-deficient female mice develop lupus-like autoimmune nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1alpha -deficient chimeric mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Yaa autoimmune phenotypes are conferred by overexpression of TLR7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Circulating plasma levels of nucleosomes in patients with systemic lupus erythematosus. Correlation with serum antinucleosome antibody titers and absence of clear association with disease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

Critical comparative analyses of anti-alpha-actinin and glomerulus-bound antibodies in human and murine lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Nucleosomes and histones are present in glomerular deposits in human lupus nephritis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Exposure of chromatin and not high affinity for dsDNA determines the nephritogenic impact of anti-dsDNA antibodies in (NZBxNZW)F1 mice

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Inefficient clearance of dying cells and autoreactivity.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Plasma levels of nucleosomes and nucleosome-autoantibody complexes in murine lupus: effects of disease progression and lipopolyssacharide administration

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Serum deoxyribonuclease I and clinical activity in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Antinucleosome antibodies and decreased deoxyribonuclease activity in sera of patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Protease yoga: extreme flexibility of a matrix metalloproteinase

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Renal expression of polyomavirus large T antigen is associated with nephritis in human systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Glomerular expression of large polyomavirus T antigen in binary tet-off regulated transgenic mice induces apoptosis, release of chromatin and initiates a lupus-like nephritis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Dnase1l3 deficiency in lupus-prone MRL and NZB/W F1 mice

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Mutually regulated expression of caspase-activated DNase and its inhibitor for apoptotic DNA fragmentation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

The experimental induction of antibodies to nucleic acids

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

The antigenic potential and specificity of nucleic acids, nucleoproteins, and their modified derivatives

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Motheaten, an Immunodeficient Mutant of the Mouse: I. Genetics and pathology

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Fas/Fas ligand deficiency results in altered localization of anti-double-stranded DNA B cells and dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.75

7 January 2021

Identifiers

DOI

10.1038/ICB.2010.75

1 reference

22 August 2017

1 reference