(Q37766226)

22 August 2017

1 reference

title

Selective inhibition of proteins regulating CDK/cyclin complexes: strategy against cancer--a review (English)

1 reference

22 August 2017

P Sarita Rajender

1

1 reference

22 August 2017

D Ramasree

2

1 reference

22 August 2017

K Bhargavi

3

1 reference

22 August 2017

M Vasavi

4

1 reference

22 August 2017

V Uma

5

1 reference

22 August 2017

1 August 2010

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Journal of Receptors and Signal Transduction

22 August 2017

1 reference

22 August 2017

30

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22 August 2017

4

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22 August 2017

206-213

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Targeting PI3K signalling in cancer: opportunities, challenges and limitations

22 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Why is cancer drug discovery so difficult?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

The challenge of cancer control in Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Paul Ehrlich's magic bullet concept: 100 years of progress.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Telomerase inhibition in cancer therapeutics: molecular-based approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Duplication of the genome in normal and cancer cell cycles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Personalised medicine for cancer: from drug development into clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Cyclins and cdks in development and cancer: a perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Checkpoints: controls that ensure the order of cell cycle events

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Cyclin/Cdk complexes: their involvement in cell cycle progression and mitotic division

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

To cycle or not to cycle: a critical decision in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Principles of CDK regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Cell cycle genes in ovarian cancer: steps toward earlier diagnosis and novel therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Cyclin-dependent kinases: engines, clocks, and microprocessors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Cell cycle, CDKs and cancer: a changing paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Recurrent head and neck cancer: current treatment and future prospects.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Bioinformatics and cancer target discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Viral transactivators E1A and VP16 interact with a large complex that is associated with CTD kinase activity and contains CDK8

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Transcriptional activating regions target attached substrates to a cyclin-dependent kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Yeast Gal4: a transcriptional paradigm revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Cdk-activating kinase complex is a component of human transcription factor TFIIH

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

TFIIH is negatively regulated by cdk8-containing mediator complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Cyclin C/cdk3 promotes Rb-dependent G0 exit

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Cyclin C makes an entry into the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Amplification and expression of cyclin D genes (CCND1, CCND2 and CCND3) in human malignant gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Physical interaction of the retinoblastoma protein with human D cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Linking cyclins to transcriptional control.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Crystal structure of human CDK4 in complex with a D-type cyclin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Oligomerization of human Gadd45a protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Genomic instability in Gadd45a-/- cells is coupled with S-phase checkpoint defects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

CDKN1C/p57kip2 is a candidate tumor suppressor gene in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Inactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Methylselenol, a selenium metabolite, induces cell cycle arrest in G1 phase and apoptosis via the extracellular-regulated kinase 1/2 pathway and other cancer signaling genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Novel strategies in cancer therapeutics: targeting enzymes involved in cell cycle regulation and cellular proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

A novel approach for the development of selective Cdk4 inhibitors: library design based on locations of Cdk4 specific amino acid residues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Truncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided design

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

Downregulation of the KIP family members p27KIP1and p57KIP2by SKP2 and the role of methylation in p57KIP2inactivation in nonsmall cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.488649

10.3109/10799893.2010.488649

21 January 2018

Identifiers

DOI

1 reference

release_yg2h3ihu6bfnzomfpqsgyvmhay

22 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yg2h3ihu6bfnzomfpqsgyvmhay

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference