(Q37766499)

22 August 2017

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title

Expression of proteinase-activated receptor 1-4 (PAR 1-4) in human cancer (English)

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22 August 2017

Andrea Pia Elste

1

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22 August 2017

Iver Petersen

series ordinal

2

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22 August 2017

publication date

1 April 2010

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Journal of Molecular Histology

22 August 2017

published in

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22 August 2017

volume

41

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22 August 2017

issue

2-3

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22 August 2017

page(s)

89-99

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Detection of functional receptors for the proteinase-activated-receptor-2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10735-010-9274-6

Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10735-010-9274-6

Stromal factors involved in prostate carcinoma metastasis to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10735-010-9274-6

Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10735-010-9274-6

Aberrant Expression and Activation of the Thrombin Receptor Protease-Activated Receptor-1 Induces Cell Proliferation and Motility in Human Colon Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10735-010-9274-6

Thrombin has a bimodal effect on glioma cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10735-010-9274-6

Concentration-dependent dual effect of thrombin on impaired growth/apoptosis or mitogenesis in tumor cells.

21 January 2018

1 reference

12 December 2020

Role of thrombin in angiogenesis and tumor progression

1 reference

12 December 2020

Signaling from protease-activated receptor-1 inhibits migration and invasion of breast cancer cells

1 reference

12 December 2020

Thrombin-mediated hepatocellular carcinoma cell migration: cooperative action via proteinase-activated receptors 1 and 4.

1 reference

12 December 2020

Proteinases, proteinase-activated receptors (PARs) and the pathophysiology of cancer and diseases of the cardiovascular, musculoskeletal, nervous and gastrointestinal systems

1 reference

12 December 2020

Protease-activated receptor-2 activation in gastric cancer cells promotes epidermal growth factor receptor trans-activation and proliferation.

1 reference

12 December 2020

Protease-activated receptor-2 expression and the role of trypsin in cell proliferation in human pancreatic cancers

1 reference

12 December 2020

Differential effects of serine proteases on the migration of normal and tumor cells: implications for tumor microenvironment

1 reference

12 December 2020

Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice

1 reference

12 December 2020

Prognosis in human melanoma: PAR-1 expression is superior to other coagulation components and VEGF.

1 reference

12 December 2020

Mammary gland tissue targeted overexpression of human protease-activated receptor 1 reveals a novel link to beta-catenin stabilization

1 reference

12 December 2020

PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells.

1 reference

12 December 2020

Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway

1 reference

12 December 2020

Role and regulation of the thrombin receptor (PAR-1) in human melanoma

1 reference

12 December 2020

Up-regulation of Flotillin-2 is associated with melanoma progression and modulates expression of the thrombin receptor protease activated receptor 1

1 reference

12 December 2020

Laboratory diagnosis of the thrombophilic state in cancer patients

1 reference

12 December 2020

Role of protease-activated receptor 1 in tumor metastasis promoted by tissue factor

1 reference

12 December 2020

Expression of protease-activated receptors 1 and 2 in melanocytic nevi and malignant melanoma

1 reference

12 December 2020

Proteinase-activated receptor-2 expression in breast cancer and the role of trypsin on growth and metabolism of breast cancer cell line MDA MB-231.

1 reference

12 December 2020

Correlation of protease-activated receptor-1 with differentiation markers in squamous cell carcinoma of the head and neck and its implication in lymph node metastasis

1 reference

12 December 2020

Formation of tissue factor-factor VIIa-factor Xa complex promotes cellular signaling and migration of human breast cancer cells

1 reference

12 December 2020

Thrombin as a survival factor for cancer cells: thrombin activation in malignant effusions in vivo and inhibition of idarubicin-induced cell death in vitro

1 reference

12 December 2020

Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis

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12 December 2020

Prognostic role of protease-activated receptors 1 and 4 in resected stage IB non-small-cell lung cancer

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12 December 2020

A functional thrombin receptor (PAR1) is expressed on bone-derived prostate cancer cell lines.

1 reference

12 December 2020

Protease-activated receptor mediated RhoA signaling and cytoskeletal reorganization in LNCaP cells

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12 December 2020

Presence of the proteinase-activated receptor-2 (PAR-2) in human brain tumor cells--trypsin- and SLIGRL-induced calcium response in primary cultured meningiomas

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12 December 2020

Microarray studies of factor VIIa-activated cancer cells

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12 December 2020

Role of proteinase-activated receptor-2 on cyclooxygenase-2 expression in H. pylori-infected gastric epithelial cells

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12 December 2020

Thrombin receptor expression is upregulated in prostate cancer.

1 reference

12 December 2020

Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2

1 reference

12 December 2020

Trypsin induces tumour necrosis factor-alpha secretion from a human leukemic mast cell line

1 reference

12 December 2020

Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment

1 reference

12 December 2020

Proteinase-activated receptors (PARs)--the PAR3 Neo-N-terminal peptide TFRGAP interacts with PAR1.

1 reference

12 December 2020

Expression of proteinase-activated receptor-2 in human pancreatic cancer: a possible relation to cancer invasion and induction of fibrosis

1 reference

12 December 2020

Thrombin induces apoptosis in human tumor cells

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12 December 2020

The pattern of Protease Activated Receptor 1 (PAR1) expression in endometrial carcinoma

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12 December 2020

Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathway

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12 December 2020

Protease-activating-receptor-2 is frequently expressed in papillary adenocarcinoma of the gallbladder

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12 December 2020

Thrombophilia in cancer

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12 December 2020

Expression of the thrombin receptor PAR-1 correlates with tumour cell differentiation of pancreatic adenocarcinoma in vitro

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12 December 2020

Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1.

1 reference

12 December 2020

Trypsin stimulates integrin alpha(5)beta(1)-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2

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12 December 2020

Thrombin receptor overexpression in malignant and physiological invasion processes

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12 December 2020

Functional thrombin receptor PAR1 in primary cultures of human glioblastoma cells

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12 December 2020

Protease-activated receptor-2 (PAR-2) in cervical cancer proliferation.

1 reference

12 December 2020

MAP kinase-mediated proliferation of DLD-1 carcinoma by the stimulation of protease-activated receptor 2

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12 December 2020

Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer

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12 December 2020

The effects of stimulating protease-activated receptor-1 and -2 in A172 human glioblastoma

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12 December 2020

Signal of proteinase-activated receptor-2 contributes to highly malignant potential of human pancreatic cancer by up-regulation of interleukin-8 release.

1 reference

12 December 2020

Mast cell tryptase stimulates DLD-1 carcinoma through prostaglandin- and MAP kinase-dependent manners

1 reference

12 December 2020

Evaluation of proteinase-activated receptor-1 (PAR1) agonists and antagonists using a cultured cell receptor desensitization assay: activation of PAR2 by PAR1-targeted ligands

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12 December 2020

The pattern of expression of protease-activated receptors (PARs) during early trophoblast development

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12 December 2020

Expression of functional protease-activated receptor 1 in human prostate cancer cell lines

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12 December 2020

Quantitative analysis of melanocytic tissue array reveals inverse correlation between activator protein-2alpha and protease-activated receptor-1 expression during melanoma progression

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12 December 2020

Protease-activated receptor (PAR)-1 and PAR-2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas

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12 December 2020

The two-receptor system PAR-1/PAR-4 mediates alpha-thrombin-induced [Ca(2+)](i) mobilization in human astrocytoma cells.

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12 December 2020

Thrombosis and cancer

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12 December 2020

Agonists of proteinase-activated receptor 2 induce TNF-alpha secretion from astrocytoma cells

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12 December 2020

Overexpression of protease-activated receptors-1,-2, and-4 (PAR-1, -2, and -4) in prostate cancer

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12 December 2020

Proteinases as hormone-like signal messengers

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12 December 2020

Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion

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12 December 2020

Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion

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12 December 2020

PAR-1- and PAR-3-type thrombin receptor expression in primary cultures of human renal cell carcinoma cells.

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12 December 2020

Human tissue kallikreins: physiologic roles and applications in cancer.

1 reference

12 December 2020

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

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12 December 2020

Expression of protease activated receptor-2 (PAR-2) in gastric cancer

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12 December 2020

Expression of protease activated receptor-2 related to angiogenesis in tumor advancement of uterine endometrial cancers

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12 December 2020

Prostate-specific kallikreins-2 and -4 enhance the proliferation of DU-145 prostate cancer cells through protease-activated receptors-1 and -2.

1 reference

12 December 2020

Expression of protease-activated receptor 1 in oral squamous cell carcinoma

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12 December 2020

Expression of protease-activated receptors and tissue factor in human liver

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12 December 2020

Tissue factor-factor VIIa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration

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12 December 2020

Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface

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12 December 2020

Thrombin generation and the pathogenesis of cancer

1 reference

12 December 2020

10.1007/S10735-010-9274-6

Identifiers

DOI

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22 August 2017

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