(Q37766696)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566661%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

review article

1 reference

title

Gating of two pore domain potassium channels (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566661%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566661%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Emma L. Veale

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566661%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

2

Ehab Al-Moubarak

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566661%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

language of work or name

English

0 references

publication date

21 June 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566661%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

published in

Journal of Physiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566661%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

volume

588

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566661%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

issue

Pt 17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566661%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

page(s)

3149-3156

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566661%20AND%20SRC:MED&resulttype=core&format=json

Molecular background of leak K+ currents: two-pore domain potassium channels

6 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Separate gating mechanisms mediate the regulation of K2P potassium channel TASK-2 by intra- and extracellular pH

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

The response of the tandem pore potassium channel TASK-3 (K(2P)9.1) to voltage: gating at the cytoplasmic mouth.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

A structural model for K2P potassium channels based on 23 pairs of interacting sites and continuum electrostatics

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

The evolutionarily conserved residue A653 plays a key role in HERG channel closing.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Gating the pore of potassium leak channels

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Emerging roles for two-pore-domain potassium channels and their potential therapeutic impact

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

A novel mechanism for human K2P2.1 channel gating. Facilitation of C-type gating by protonation of extracellular histidine residues

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Molecular driving forces determining potassium channel slow inactivation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Identification of a region in the TASK3 two pore domain potassium channel that is critical for its blockade by methanandamide.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Therapeutic potential of neuronal two-pore domain potassium-channel modulators

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Biophysical, pharmacological, and functional characteristics of cloned and native mammalian two-pore domain K+ channels

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Determinants of the anesthetic sensitivity of two-pore domain acid-sensitive potassium channels: molecular cloning of an anesthetic-activated potassium channel from Lymnaea stagnalis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

The selectivity, voltage-dependence and acid sensitivity of the tandem pore potassium channel TASK-1: contributions of the pore domains.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

The neuronal background K2P channels: focus on TREK1

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Neutralization of a single arginine residue gates open a two-pore domain, alkali-activated K+ channel

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Neuronal two-pore-domain potassium channels and their regulation by G protein-coupled receptors

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Cross talk between activation and slow inactivation gates of Shaker potassium channels

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Modifying the subunit composition of TASK channels alters the modulation of a leak conductance in cerebellar granule neurons.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

A phospholipid sensor controls mechanogating of the K+ channel TREK-1.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Functional expression of TASK-1/TASK-3 heteromers in cerebellar granule cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

X-ray structure of a voltage-dependent K+ channel

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Ruthenium red inhibits TASK-3 potassium channel by interconnecting glutamate 70 of the two subunits.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

The voltage-gated potassium channels and their relatives

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

An intracellular proton sensor commands lipid- and mechano-gating of the K(+) channel TREK-1.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

The open pore conformation of potassium channels

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: volatile anesthetics and neurotransmitters share a molecular site of action

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

KCNKØ: opening and closing the 2-P-domain potassium leak channel entails "C-type" gating of the outer pore.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

TASK-5, a novel member of the tandem pore K+ channel family

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

A conserved glutamate is important for slow inactivation in K+ channels.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

TREK-1 is a heat-activated background K(+) channel

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

TASK-3, a novel tandem pore domain acid-sensitive K+ channel. An extracellular histiding as pH sensor

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

TASK-3, a new member of the tandem pore K(+) channel family

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

A functional role for the two-pore domain potassium channel TASK-1 in cerebellar granule neurons

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Inhalational anesthetics activate two-pore-domain background K+ channels

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

TASK, a human background K+ channel to sense external pH variations near physiological pH

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Comparative protein modelling by satisfaction of spatial restraints

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated K+ channels

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

Two types of inactivation in Shaker K+ channels: effects of alterations in the carboxy-terminal region.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976010

G(alpha)q-mediated regulation of TASK3 two-pore domain potassium channels: the role of protein kinase C

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20566661

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inverse coupling in leak and voltage-activated K+ channel gates underlies distinct roles in electrical signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20566661

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1113/JPHYSIOL.2010.192344

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566661%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PMC publication ID

2976010

0 references

1 reference