(Q37773241)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635898%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

review article

1 reference

title

MUC1 immunotherapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635898%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635898%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Richard E Beatson

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635898%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Joyce Taylor-Papadimitriou

series ordinal

2

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7 February 2020

publication date

1 May 2010

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7 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635898%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

2

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7 February 2020

issue

3

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7 February 2020

page(s)

305-327

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Cancer immunotherapy: moving beyond current vaccines

7 February 2020

cites work

1 reference

21 January 2018

Cancer statistics, 2001

1 reference

MUC1 and the immunobiology of cancer

21 January 2018

1 reference

MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

21 January 2018

1 reference

MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy

21 January 2018

1 reference

Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding

21 January 2018

1 reference

MT1-MMP mediates MUC1 shedding independent of TACE/ADAM17.

21 January 2018

1 reference

MUC1, the renaissance molecule

21 January 2018

1 reference

Cloning of partial cDNA encoding differentiation and tumor-associated mucin glycoproteins expressed by human mammary epithelium

21 January 2018

1 reference

O-linked glycosylation in the mammary gland: changes that occur during malignancy.

21 January 2018

1 reference

Hypervariability of the membrane-associated mucin and cancer marker MUC1.

21 January 2018

1 reference

The epithelial mucin, MUC1, of milk, mammary gland and other tissues

21 January 2018

1 reference

Cell surface-associated mucins in signal transduction

21 January 2018

1 reference

Structure and function of the cell surface (tethered) mucins

21 January 2018

1 reference

Form and pattern of MUC1 expression on T cells activated in vivo or in vitro suggests a function in T-cell migration.

21 January 2018

1 reference

Mucin1 expression is enriched in the human stem cell fraction of cord blood and is upregulated in majority of the AML cases.

21 January 2018

1 reference

From tumor antigens to immunotherapy

21 January 2018

1 reference

Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells.

21 January 2018

1 reference

Prognostic value of FHIT, CTNNB1, and MUC1 expression in non-small cell lung cancer

21 January 2018

1 reference

Cancer specific Mucin-1 glycoforms are expressed on multiple myeloma.

21 January 2018

1 reference

Comparative immunohistochemical study of MUC1 and carbohydrate antigens in breast benign disease and normal mammary gland.

21 January 2018

1 reference

A transfected sialyltransferase that is elevated in breast cancer and localizes to the medial/trans-Golgi apparatus inhibits the development of core-2-based O-glycans

21 January 2018

1 reference

The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1.

21 January 2018

1 reference

Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells.

21 January 2018

1 reference

The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.

21 January 2018

1 reference

ST6GalNAc I expression in MDA-MB-231 breast cancer cells greatly modifies their O-glycosylation pattern and enhances their tumourigenicity.

21 January 2018

1 reference

Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen

21 January 2018

1 reference

The importance of MUC1 cellular localization in patients with breast carcinoma: an immunohistologic study of 71 patients and review of the literature

21 January 2018

1 reference

Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components

21 January 2018

1 reference

Expression of tumor-associated differentiation antigens, MUC1 glycoforms and CEA, in human thymic epithelial cells: implications for self-tolerance and tumor therapy

21 January 2018

1 reference

Survival in early breast cancer patients is favorably influenced by a natural humoral immune response to polymorphic epithelial mucin.

21 January 2018

1 reference

Humoral immune response to abnormal MUC1 in subjects with colorectal adenoma and cancer

21 January 2018

1 reference

Breast cancer humoral immune response: involvement of Lewis y through the detection of circulating immune complexes and association with Mucin 1 (MUC1).

21 January 2018

1 reference

Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow.

21 January 2018

1 reference

Effects of distant metastasis and peripheral CA 15-3 on the induction of spontaneous T cell responses in breast cancer patients.

21 January 2018

1 reference

Enrichment of functional CD8 memory T cells specific for MUC1 in bone marrow of patients with multiple myeloma.

21 January 2018

1 reference

The expression of MUC1 in human Fallopian tube during the menstrual cycle and in ectopic pregnancy.

21 January 2018

1 reference

Antibodies to the cytoplasmic domain of the MUC1 mucin show conservation throughout mammals

21 January 2018

1 reference

Functional targeting of the MUC1 oncogene in human cancers

21 January 2018

1 reference

MUC1 alters beta-catenin-dependent tumor formation and promotes cellular invasion

21 January 2018

1 reference

MUC1 oncoprotein promotes refractoriness to chemotherapy in thyroid cancer cells

21 January 2018

1 reference

The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma.

21 January 2018

1 reference

Tumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells

21 January 2018

1 reference

Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland

21 January 2018

1 reference

The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin

21 January 2018

1 reference

Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response

21 January 2018

1 reference

MUC1 oncoprotein suppresses activation of the ARF-MDM2-p53 pathway

21 January 2018

1 reference

MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation

21 January 2018

1 reference

The polymorphic epithelial mucin: potential as an immunogen for a cancer vaccine

21 January 2018

1 reference

Combined gemcitabine and radioimmunotherapy for the treatment of pancreatic cancer

21 January 2018

1 reference

Phase III trial of intraperitoneal therapy with yttrium-90-labeled HMFG1 murine monoclonal antibody in patients with epithelial ovarian cancer after a surgically defined complete remission

21 January 2018

1 reference

HER-2 signaling and inhibition in breast cancer

21 January 2018

1 reference

High level of MUC1 in serum of ovarian and breast cancer patients inhibits huHMFG-1 dependent cell-mediated cytotoxicity (ADCC).

21 January 2018

1 reference

The O-linked glycosylation of secretory/shed MUC1 from an advanced breast cancer patient's serum

21 January 2018

1 reference

Polymorphic epithelial mucin (MUC-1)-containing circulating immune complexes in carcinoma patients

21 January 2018

1 reference

NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3.

21 January 2018

1 reference

Efficient production of human bivalent and trivalent anti-MUC1 Fab-scFv antibodies in Pichia pastoris

21 January 2018

1 reference

Production and characterization of anti-(mucin MUC1) single-domain antibody in tobacco (Nicotiana tabacum cultivar Xanthi).

21 January 2018

1 reference

Adoptive cell transfer: a clinical path to effective cancer immunotherapy

21 January 2018

1 reference

MUC1-specific CTLs are non-functional within a pancreatic tumor microenvironment

21 January 2018

1 reference

MHC antigens and tumor escape from immune surveillance

21 January 2018

1 reference

Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ /CD28 receptor

21 January 2018

1 reference

Retargeting of human T cells to tumor-associated MUC1: the evolution of a chimeric antigen receptor

21 January 2018

1 reference

Review of current knowledge on HPV vaccination: an appendix to the European Guidelines for Quality Assurance in Cervical Cancer Screening

21 January 2018

1 reference

Anti-MUC1 class I restricted CTLs in metastatic breast cancer patients immunized with a synthetic MUC1 peptide

21 January 2018

1 reference

Ex vivo targeting of the macrophage mannose receptor generates anti-tumor CTL responses.

21 January 2018

1 reference

Pilot phase III immunotherapy study in early-stage breast cancer patients using oxidized mannan-MUC1 [ISRCTN71711835].

21 January 2018

1 reference

Strategies used for MUC1 immunotherapy: human clinical studies

21 January 2018

1 reference

Mannan derivatives induce phenotypic and functional maturation of mouse dendritic cells.

21 January 2018

1 reference

Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.

21 January 2018

1 reference

Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice

21 January 2018

1 reference

Expression of sialyl-Tn predicts the effect of adjuvant chemotherapy in node-positive breast cancer

21 January 2018

1 reference

A randomised phase II study of sialyl-Tn and DETOX-B adjuvant with or without cyclophosphamide pretreatment for the active specific immunotherapy of breast cancer

21 January 2018

1 reference

Vaccination with Theratope (STn-KLH) as treatment for breast cancer

21 January 2018

1 reference

Sialyl-Tn vaccine induces antibody-mediated tumour protection in a relevant murine model

21 January 2018

1 reference

Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer

21 January 2018

1 reference

Mannan-MUC1-pulsed dendritic cell immunotherapy: a phase I trial in patients with adenocarcinoma.

21 January 2018

1 reference

Dendritic cells in vaccination therapies of malignant diseases

21 January 2018

1 reference

Breast carcinoma cell lysate-pulsed dendritic cells cross-prime MUC1-specific CD8+ T cells identified by peptide-MHC-class-I tetramers.

21 January 2018

1 reference

Fusion cell vaccination of patients with metastatic breast and renal cancer induces immunological and clinical responses

21 January 2018

1 reference

Dendritic cell-tumor fusion vaccines for renal cell carcinoma

21 January 2018

1 reference

Processing and presentation of HLA class I and II epitopes by dendritic cells after transfection with in vitro-transcribed MUC1 RNA.

21 January 2018

1 reference

Autologous MUC1-specific Th1 effector cell immunotherapy induces differential levels of systemic TReg cell subpopulations that result in increased ovarian cancer patient survival

21 January 2018

1 reference

Fusions of dendritic cells with breast carcinoma stimulate the expansion of regulatory T cells while concomitant exposure to IL-12, CpG oligodeoxynucleotides, and anti-CD3/CD28 promotes the expansion of activated tumor reactive cells

21 January 2018

1 reference

Cancer immunotherapy by fusions of dendritic cells and tumor cells

21 January 2018

1 reference

Transfection of dendritic cells with RNA induces CD4- and CD8-mediated T cell immunity against breast carcinomas and reveals the immunodominance of presented T cell epitopes

21 January 2018

1 reference

Immunisation with 'naïve' syngeneic dendritic cells protects mice from tumour challenge.

21 January 2018

1 reference

Protection against MUC1 expressing mouse tumours by intra-muscular injection of MUC1 cDNA requires functional CD8+ and CD4+ T cells but does not require the MUC1 tandem repeat domain

21 January 2018

1 reference

Long-term tumor growth suppression in mice immunized with naked DNA of the human tumor antigen mucin (MUC1).

21 January 2018

1 reference

Metastatic Breast Tumour Regression Following Treatment by a Gene-Modified Vaccinia Virus Expressing MUC1 and IL-2

21 January 2018

1 reference

A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV Non-small cell lung cancer

21 January 2018

1 reference

Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer

21 January 2018

1 reference

Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma

21 January 2018

1 reference

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

21 January 2018

1 reference

Cross-presenting human gammadelta T cells induce robust CD8+ alphabeta T cell responses

21 January 2018

1 reference

Identification of O-glycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes

21 January 2018

1 reference

Complex carbohydrates are not removed during processing of glycoproteins by dendritic cells: processing of tumor antigen MUC1 glycopeptides for presentation to major histocompatibility complex class II-restricted T cells

21 January 2018

1 reference

Presentation of cytosolic glycosylated peptides by human class I major histocompatibility complex molecules in vivo

21 January 2018

1 reference

O-glycosylated versus non-glycosylated MUC1-derived peptides as potential targets for cytotoxic immunotherapy of carcinoma.

21 January 2018

1 reference

A glycopeptide in complex with MHC class I uses the GalNAc residue as an anchor

21 January 2018

1 reference

Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity

21 January 2018

1 reference

MUC1 immunobiology: from discovery to clinical applications

21 January 2018

1 reference

Glycosylation and the immune system

21 January 2018

1 reference

Designer glycopeptides for cytotoxic T cell-based elimination of carcinomas

21 January 2018

1 reference

Recognition of carbohydrate by major histocompatibility complex class I-restricted, glycopeptide-specific cytotoxic T lymphocytes

21 January 2018

1 reference

Mucin-type O-glycosylation and its potential use in drug and vaccine development

21 January 2018

1 reference

Immune recognition of a human renal cancer antigen through post-translational protein splicing.

21 January 2018

1 reference

alpha v beta3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen.

21 January 2018

1 reference

Endogenous MHC class II processing of a viral nuclear antigen after autophagy.

21 January 2018

1 reference

Destructive cleavage of antigenic peptides either by the immunoproteasome or by the standard proteasome results in differential antigen presentation

21 January 2018

1 reference

Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors

21 January 2018

1 reference

Proteasome inhibitors: antitumor effects and beyond

21 January 2018

1 reference

MHC-unrestricted lysis of MUC1-expressing cells by human peripheral blood mononuclear cells

21 January 2018

1 reference

Therapeutic potential of a tumor-specific, MHC-unrestricted T-cell receptor expressed on effector cells of the innate and the adaptive immune system through bone marrow transduction and immune reconstitution.

21 January 2018

1 reference

Lentiviral vectors encoding human MUC1-specific, MHC-unrestricted single-chain TCR and a fusion suicide gene: potential for universal and safe cancer immunotherapy

21 January 2018

1 reference

Cancer and the tumor microenvironment: a review of an essential relationship

21 January 2018

1 reference

Immunosuppressive strategies that are mediated by tumor cells

21 January 2018

1 reference

Intratumoral Cytokines and Tumor Cell Biology Determine Spontaneous Breast Cancer-Specific Immune Responses and Their Correlation to Prognosis

21 January 2018

1 reference

Tumor burden influences cytotoxic T cell development in metastatic breast cancer patients--a phase I/II study

21 January 2018

1 reference

A MUC1 mucin secreted from a colon carcinoma cell line inhibits target cell lysis by natural killer cells

21 January 2018

1 reference

Enhanced production of interleukin 6 in peripheral blood monocytes stimulated with mucins secreted into the bloodstream

21 January 2018

1 reference

Mucin-induced apoptosis of monocyte-derived dendritic cells during maturation

21 January 2018

1 reference

Recombinant tumor-associated MUC1 glycoprotein impairs the differentiation and function of dendritic cells

21 January 2018

1 reference

Tumor-derived MUC1 mucins interact with differentiating monocytes and induce IL-10highIL-12low regulatory dendritic cell

21 January 2018

1 reference

MUC1 and sialoglycan expression associated with cytotoxic T lymphocyte infiltration in eyelid malignant tumors

21 January 2018

1 reference

MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma

21 January 2018

1 reference

Urokinase-mediated recruitment of myeloid-derived suppressor cells and their suppressive mechanisms are blocked by MUC1/sec

21 January 2018

1 reference

A minimal fragment of MUC1 mediates growth of cancer cells

21 January 2018

1 reference

MUC1* mediates the growth of human pluripotent stem cells

21 January 2018

1 reference

Intracellular MUC1 peptides inhibit cancer progression

21 January 2018

1 reference

Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells

21 January 2018

1 reference

Tumor-derived exosomes: a new source of tumor rejection antigens

21 January 2018

1 reference

Exosomes: a new delivery system for tumor antigens in cancer immunotherapy.

21 January 2018

1 reference

HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine DC.

21 January 2018

1 reference

Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo

21 January 2018

1 reference

Targeting of antigens to B cells augments antigen-specific T-cell responses and breaks immune tolerance to tumor-associated antigen MUC1

21 January 2018

1 reference

Role of gammadelta T lymphocytes in tumor defense

21 January 2018

1 reference

Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes

21 January 2018

1 reference

Combination chemotherapy and radiation of human squamous cell carcinoma of the head and neck augments CTL-mediated lysis.

21 January 2018

1 reference

New rationales for using TGFbeta inhibitors in radiotherapy

21 January 2018

1 reference

Immunological aspects of cancer chemotherapy

21 January 2018

1 reference

Progression of pancreatic adenocarcinoma is significantly impeded with a combination of vaccine and COX-2 inhibition.

21 January 2018

1 reference

Effective anti-tumor responses induced by recombinant bacillus Calmette-Guérin vaccines based on different tandem repeats of MUC1 and GM-CSF.

21 January 2018

1 reference

MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1.

21 January 2018

1 reference

Differentiation antigens expressed by epithelial cells in the lactating breast are also detectable in breast cancers

21 January 2018

1 reference

Selection and characterization of MUC1-specific CD8+ T cells from MUC1 transgenic mice immunized with dendritic-carcinoma fusion cells

21 January 2018

1 reference

An Autologous Therapeutic Dendritic Cell Vaccine Transfected with Total Lung Carcinoma RNA Stimulates Cytotoxic T Lymphocyte Responses Against Non-Small Cell Lung Cancer

21 January 2018

1 reference