(Q37774322)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20645321%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

review article

1 reference

title

Function of the intestinal epithelium and its dysregulation in inflammatory bowel disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20645321%20AND%20SRC:MED&resulttype=core&format=json

inflammatory bowel diseases

8 February 2020

main subject

0 references

0 references

1

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8 February 2020

Jürgen Schwarze

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20645321%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Johan E van Limbergen

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20645321%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

David C Wilson

series ordinal

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20645321%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

publication date

1 January 2011

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Inflammatory Bowel Diseases

8 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20645321%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

17

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8 February 2020

issue

1

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8 February 2020

page(s)

382-395

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20645321%20AND%20SRC:MED&resulttype=core&format=json

Intestinal barrier dysfunction in inflammatory bowel diseases.

8 February 2020

cites work

1 reference

Filaggrin loss-of-function variants are associated with atopic comorbidity in pediatric inflammatory bowel disease

21 January 2018

1 reference

Stem cells, self-renewal, and differentiation in the intestinal epithelium

21 January 2018

1 reference

In vitro models of intestinal epithelial cell differentiation

21 January 2018

1 reference

Defensins and inflammation: the role of defensins in inflammatory bowel disease

21 January 2018

1 reference

The role of enterocytes in the intestinal barrier function and antigen uptake.

21 January 2018

1 reference

Functional differences between M cells and enterocytes in sampling luminal antigens

21 January 2018

1 reference

Epithelial M cells: differentiation and function

21 January 2018

1 reference

RANKL Is Necessary and Sufficient to Initiate Development of Antigen-Sampling M Cells in the Intestinal Epithelium

21 January 2018

1 reference

Cell culture modeling of specialized tissue: identification of genes expressed specifically by follicle-associated epithelium of Peyer's patch by expression profiling of Caco-2/Raji co-cultures.

21 January 2018

1 reference

Reciprocal interactions between commensal bacteria and gamma delta intraepithelial lymphocytes during mucosal injury

21 January 2018

1 reference

Intraepithelial lymphocytes: exploring the Third Way in immunology

21 January 2018

1 reference

Human CD8+ intraepithelial lymphocytes: a unique model to study the regulation of effector cytotoxic T lymphocytes in tissue

21 January 2018

1 reference

Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

21 January 2018

1 reference

IL-15 protects intestinal epithelial cells

21 January 2018

1 reference

The genetics of chronic inflammatory diseases

21 January 2018

1 reference

Higher constitutive IL15R alpha expression and lower IL-15 response threshold in coeliac disease patients.

21 January 2018

1 reference

Intraepithelial lymphocytes: their shared and divergent immunological behaviors in the small and large intestine

21 January 2018

1 reference

Generation of gut-homing T cells and their localization to the small intestinal mucosa

21 January 2018

1 reference

CCR9-positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease.

21 January 2018

1 reference

T-lymphocyte-epithelial-cell interactions: integrin alpha(E)(CD103)beta(7), LEEP-CAM and chemokines.

21 January 2018

1 reference

Role of beta7 integrin and the chemokine/chemokine receptor pair CCL25/CCR9 in modeled TNF-dependent Crohn's disease.

21 January 2018

1 reference

Expression of lymphocyte-endothelial receptor-ligand pairs, alpha4beta7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease

21 January 2018

1 reference

CD8+ recent thymic emigrants home to and efficiently repopulate the small intestine epithelium

21 January 2018

1 reference

Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin

21 January 2018

1 reference

Molecular mechanism of intestinal permeability: interaction at tight junctions

21 January 2018

1 reference

Epithelial transport and barrier function in occludin-deficient mice

21 January 2018

1 reference

Polymorphisms in E-cadherin (CDH1) result in a mis-localised cytoplasmic protein that is associated with Crohn's disease

21 January 2018

1 reference

A porous defense: the leaky epithelial barrier in intestinal disease.

21 January 2018

1 reference

Different intestinal permeability patterns in relatives and spouses of patients with Crohn's disease: an inherited defect in mucosal defence?

21 January 2018

1 reference

Correlation between cyclical epithelial barrier dysfunction and bacterial translocation in the relapses of intestinal inflammation

21 January 2018

1 reference

Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation?

21 January 2018

1 reference

Invasive Escherichia coli are a feature of Crohn's disease

21 January 2018

1 reference

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

21 January 2018

1 reference

Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease

21 January 2018

1 reference

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

1 reference

Protection of epithelial barrier function by the Crohn's disease associated gene protein tyrosine phosphatase n2

21 January 2018

1 reference

Increased susceptibility to dextran sulfate sodium induced colitis in the T cell protein tyrosine phosphatase heterozygous mouse

21 January 2018

1 reference

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease

21 January 2018

1 reference

A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease.

21 January 2018

1 reference

Molecular mechanism of tumor necrosis factor-alpha modulation of intestinal epithelial tight junction barrier

21 January 2018

1 reference

Intestinal barrier function: molecular regulation and disease pathogenesis

21 January 2018

1 reference

Epithelia: lymphocyte interactions in the gut.

21 January 2018

1 reference

Patterns and scales in gastrointestinal microbial ecology

21 January 2018

1 reference

A human gut microbial gene catalogue established by metagenomic sequencing

21 January 2018

1 reference

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

Getting to the guts of NOD2.

21 January 2018

1 reference

Nod2 is required for the regulation of commensal microbiota in the intestine

21 January 2018

1 reference

MAST3: a novel IBD risk factor that modulates TLR4 signaling

21 January 2018

1 reference

Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease

21 January 2018

1 reference

Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells

21 January 2018

1 reference

The role of epithelial Toll-like receptor signaling in the pathogenesis of intestinal inflammation

21 January 2018

1 reference

Crohn's disease is associated with a toll-like receptor-9 polymorphism

21 January 2018

1 reference

TLR2, TLR4 and TLR9 polymorphisms and Crohn's disease in a New Zealand Caucasian cohort

21 January 2018

1 reference

Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP.

21 January 2018

1 reference

The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens

21 January 2018

1 reference

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

21 January 2018

1 reference

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

21 January 2018

1 reference

Role of mucosal dendritic cells in inflammatory bowel disease

21 January 2018

1 reference

How intestinal epithelial cells tolerise dendritic cells and its relevance to inflammatory bowel disease

21 January 2018

1 reference

The yin and yang of intestinal epithelial cells in controlling dendritic cell function

21 January 2018

1 reference

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

21 January 2018

1 reference

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5.

21 January 2018

1 reference

Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells

21 January 2018

1 reference

Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells

21 January 2018

1 reference

Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells.

21 January 2018

1 reference

A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes

21 January 2018

1 reference

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

21 January 2018

1 reference

E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis.

21 January 2018

1 reference

TGF-beta1 gene-modified, immature dendritic cells delay the development of inflammatory bowel disease by inducing CD4(+)Foxp3(+) regulatory T cells

21 January 2018

1 reference

Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders

21 January 2018

1 reference

Antigen presentation by intestinal epithelial cells

21 January 2018

1 reference

Endocytosis of cholera toxin by human enterocytes is developmentally regulated

21 January 2018

1 reference

Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn.

21 January 2018

1 reference

An FcRn-dependent role for anti-flagellin immunoglobulin G in pathogenesis of colitis in mice.

21 January 2018

1 reference

A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population

21 January 2018

1 reference

Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing

21 January 2018

1 reference

Multivesicular bodies in intestinal epithelial cells: responsible for MHC class II-restricted antigen processing and origin of exosomes.

21 January 2018

1 reference

Increased epithelial uptake of protein antigens in the ileum of Crohn's disease mediated by tumour necrosis factor alpha

21 January 2018

1 reference

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

21 January 2018

1 reference

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

1 reference

Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant

21 January 2018

1 reference

Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly

21 January 2018

1 reference

21 January 2018

1 reference

Regulation of macrophage motility by Irgm1

21 January 2018

1 reference

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

21 January 2018

1 reference

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

21 January 2018

1 reference

Comparative expression analysis and characterization of 20S proteasomes in human intestinal tissues: The proteasome pattern as diagnostic tool for IBD patients.

21 January 2018

1 reference

MHC class II expression by the gut epithelium

21 January 2018

1 reference

Non-classical MHC class I molecules on intestinal epithelial cells: mediators of mucosal crosstalk

21 January 2018

1 reference

Novel MHC class I-related molecule MR1 affects MHC class I expression in 293T cells

21 January 2018

1 reference

Cd1d-dependent regulation of bacterial colonization in the intestine of mice

21 January 2018

1 reference

Phenotypic and functional characterization of intestinal epithelial exosomes

21 January 2018

1 reference

Human small intestinal epithelial cells constitutively express the key elements for antigen processing and the production of exosomes

21 January 2018

1 reference

Defensins and other antimicrobial peptides in inflammatory bowel disease

21 January 2018

1 reference

Crohn's disease: a defensin deficiency syndrome?

21 January 2018

1 reference

Reduced Paneth cell alpha-defensins in ileal Crohn's disease

21 January 2018

1 reference

Heterogeneous expression of human cathelicidin hCAP18/LL-37 in inflammatory bowel diseases

21 January 2018

1 reference

A C-type lectin MGL1/CD301a plays an anti-inflammatory role in murine experimental colitis

21 January 2018

1 reference

Specific association of a CLEC16A/KIAA0350 polymorphism with NOD2/CARD15(-) Crohn's disease patients

21 January 2018

1 reference

The biology of intestinal immunoglobulin A responses

21 January 2018

1 reference

Immunoglobulin A: Fc(alpha)RI interactions induce neutrophil migration through release of leukotriene B4.

21 January 2018

1 reference

Biological therapies for inflammatory bowel diseases

21 January 2018

1 reference

Selecting appropriate anti-TNF agents in inflammatory bowel disease

21 January 2018

1 reference

Rapid infliximab infusions in pediatric inflammatory bowel disease

21 January 2018

1 reference

Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease.

21 January 2018

1 reference

Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children.

21 January 2018

1 reference

Efficacy of infliximab in pediatric Crohn's disease: a randomized multicenter open-label trial comparing scheduled to on demand maintenance therapy

21 January 2018

1 reference

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

21 January 2018

1 reference

IL-21 and IL-21 Receptor: A New Cytokine Pathway Modulates Innate and Adaptive Immunity

21 January 2018

1 reference

Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation

21 January 2018

1 reference

Regulation of gut inflammation and th17 cell response by interleukin-21.

21 January 2018

1 reference

New players in the cytokine orchestra of inflammatory bowel disease

21 January 2018

1 reference

Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor

21 January 2018

1 reference

Acinar cells of the pancreas are a target of interleukin-22.

21 January 2018

1 reference

IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not.

21 January 2018

1 reference

Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells.

21 January 2018

1 reference

Serum amyloid A activates NF-kappaB and proinflammatory gene expression in human and murine intestinal epithelial cells.

21 January 2018

1 reference

Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice

21 January 2018

1 reference

Structures and biological functions of IL-31 and IL-31 receptors

21 January 2018

1 reference

Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.

21 January 2018

1 reference

Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells

21 January 2018

1 reference

IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism

21 January 2018

1 reference

Chemokines and chemokine receptors in mucosal homeostasis at the intestinal epithelial barrier in inflammatory bowel disease

21 January 2018

1 reference

Mucosal angiogenesis regulation by CXCR4 and its ligand CXCL12 expressed by human intestinal microvascular endothelial cells

21 January 2018

1 reference

Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4.

21 January 2018

1 reference

Rho activation regulates CXCL12 chemokine stimulated actin rearrangement and restitution in model intestinal epithelia.

21 January 2018

1 reference

Chemokine expression in IBD. Mucosal chemokine expression is unselectively increased in both ulcerative colitis and Crohn's disease.

21 January 2018

1 reference

Increased expression of MIP-3alpha/CCL20 in peripheral blood mononuclear cells from patients with ulcerative colitis and its down-regulation by sulfasalazine and glucocorticoid treatment

21 January 2018

1 reference

Atorvastatin reduces plasma levels of chemokine (CXCL10) in patients with Crohn's disease

21 January 2018

1 reference

A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.

21 January 2018

1 reference

Human intestinal epithelial cell lines produce factor(s) that inhibit CD3-mediated T-lymphocyte proliferation

21 January 2018

1 reference

Colonic epithelial cell mediated suppression of CD4 T cell activation.

21 January 2018

1 reference

Epithelial cells bearing class II molecules stimulate allogeneic human colonic intraepithelial lymphocytes

21 January 2018

1 reference

Stimulation of lamina propria lymphocytes by intestinal epithelial cells: evidence for recognition of nonclassical restriction elements

21 January 2018

1 reference

The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells

21 January 2018

1 reference

Common variants at five new loci associated with early-onset inflammatory bowel disease

21 January 2018

1 reference

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

21 January 2018

1 reference

Lack of induction of suppressor T cells by intestinal epithelial cells from patients with inflammatory bowel disease

21 January 2018

1 reference

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

21 January 2018

1 reference

Oral tolerance: intestinal homeostasis and antigen-specific regulatory T cells

21 January 2018

1 reference

Antigen-specific CD4(+) regulatory T cells in the intestine

21 January 2018

1 reference

Regulatory lymphocytes and intestinal inflammation.

21 January 2018

1 reference

Regulatory T cells in inflammatory bowel disease

21 January 2018

1 reference

Interleukin-10-deficient mice develop chronic enterocolitis

21 January 2018

1 reference

A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.

21 January 2018

1 reference

Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria

21 January 2018

1 reference

Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract

21 January 2018

1 reference

Reconstitution of cultured intestinal epithelial monolayers with a mucosal-derived T lymphocyte cell line. Modulation of epithelial phenotype dependent on lymphocyte-basolateral membrane apposition

21 January 2018

1 reference

Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches.

21 January 2018

1 reference

Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury

21 January 2018

1 reference

Haplotype-based association analysis of 56 functional candidate genes in the IBD6 locus on chromosome 19

21 January 2018

1 reference

A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease

21 January 2018

1 reference

Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IBD.21379

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20645321%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference