(Q37775278)

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Novel strategies and approaches to develop the next generation of vaccines against porcine reproductive and respiratory syndrome virus (PRRSV).

scientific article published on 23 July 2010

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Europe PubMed Central

23 August 2017

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Europe PubMed Central

22 October 2022

Novel strategies and approaches to develop the next generation of vaccines against porcine reproductive and respiratory syndrome virus (PRRSV). (English)

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Europe PubMed Central

23 August 2017

porcine reproductive and respiratory syndrome

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porcine reproductive and respiratory syndrome virus

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porcine reproductive and respiratory syndrome virus

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based on heuristic

inferred from title

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Y W Huang

1

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Europe PubMed Central

23 August 2017

X J Meng

2

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Europe PubMed Central

23 August 2017

publication date

23 July 2010

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Europe PubMed Central

23 August 2017

1 December 2010

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22 October 2022

2 references

Europe PubMed Central

23 August 2017

22 October 2022

154

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Europe PubMed Central

23 August 2017

1-2

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Europe PubMed Central

23 August 2017

141-149

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Europe PubMed Central

23 August 2017

Porcine reproductive and respiratory syndrome virus: description of persistence in individual pigs upon experimental infection

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Diagnosis of PRRS.

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Appearance of acute PRRS-like symptoms in sow herds after vaccination with a modified live PRRS vaccine

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Infectious transcripts and cDNA clones of RNA viruses.

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CD163 expression confers susceptibility to porcine reproductive and respiratory syndrome viruses

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Phenotypic and functional modulation of bone marrow-derived dendritic cells by porcine reproductive and respiratory syndrome virus

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Effects of porcine reproductive and respiratory syndrome virus-infected antigen-presenting cells on T cell activation and antiviral cytokine production

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Toll-Like Receptor expressions in porcine alveolar macrophages and Dendritic Cells in responding to poly IC stimulation and porcine reproductive and respiratory syndrome virus (PRRSV) infection

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Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: nsp1 function as interferon antagonist

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Immunodominant epitopes in nsp2 of porcine reproductive and respiratory syndrome virus are dispensable for replication, but play an important role in modulation of the host immune response

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Identification of 5' and 3' cis-acting elements of the porcine reproductive and respiratory syndrome virus: acquisition of novel 5' AU-rich sequences restored replication of a 5'-proximal 7-nucleotide deletion mutant

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Isolation of swine infertility and respiratory syndrome virus (isolate ATCC VR-2332) in North America and experimental reproduction of the disease in gnotobiotic pigs

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Porcine reproductive and respiratory syndrome virus-infected alveolar macrophages contain no detectable levels of viral proteins in their plasma membrane and are protected against antibody-dependent, complement-mediated cell lysis

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The minor envelope glycoproteins GP2a and GP4 of porcine reproductive and respiratory syndrome virus interact with the receptor CD163.

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The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host

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Development of a porcine reproductive and respiratory syndrome virus differentiable (DIVA) strain through deletion of specific immunodominant epitopes.

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Serologic marker candidates identified among B-cell linear epitopes of Nsp2 and structural proteins of a North American strain of porcine reproductive and respiratory syndrome virus.

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Current knowledge on the structural proteins of porcine reproductive and respiratory syndrome (PRRS) virus: comparison of the North American and European isolates

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Porcine reproductive and respiratory syndrome: clinical disease, pathology and immunosuppression

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Vaccine efficacy of porcine reproductive and respiratory syndrome virus chimeras

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Neutralizing antibody responses of pigs infected with natural GP5 N-glycan mutants of porcine reproductive and respiratory syndrome virus

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Development of genetic markers in the non-structural protein 2 region of a US type 1 porcine reproductive and respiratory syndrome virus: implications for future recombinant marker vaccine development

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A full-length cDNA infectious clone of North American type 1 porcine reproductive and respiratory syndrome virus: expression of green fluorescent protein in the Nsp2 region

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Porcine reproductive and respiratory syndrome virus infects mature porcine dendritic cells and up-regulates interleukin-10 production

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Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases.

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Nidovirales: evolving the largest RNA virus genome

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Infection of porcine alveolar macrophages with recombinant chimeric porcine reproductive and respiratory syndrome virus: effects on cellular gene transcription and virus growth

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Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis

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Porcine DC-SIGN: molecular cloning, gene structure, tissue distribution and binding characteristics.

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Identification and characterization of a porcine monocytic cell line supporting porcine reproductive and respiratory syndrome virus (PRRSV) replication and progeny virion production by using an improved DNA-launched PRRSV reverse genetics system.

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Identification of a porcine DC-SIGN-related C-type lectin, porcine CLEC4G (LSECtin), and its order of intron removal during splicing: comparative genomic analyses of the cluster of genes CD23/CLEC4G/DC-SIGN among mammalian species

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Humoral immune response induced by oral administration of S. typhimurium containing a DNA vaccine against porcine reproductive and respiratory syndrome virus

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Enhanced immune responses of mice inoculated recombinant adenoviruses expressing GP5 by fusion with GP3 and/or GP4 of PRRS virus

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Immunogenicity and protective efficacy of recombinant pseudorabies virus expressing the two major membrane-associated proteins of porcine reproductive and respiratory syndrome virus

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DNA vaccines co-expressing GP5 and M proteins of porcine reproductive and respiratory syndrome virus (PRRSV) display enhanced immunogenicity

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Genetic variation in porcine reproductive and respiratory syndrome virus isolates in the midwestern United States

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Genetic variation and phylogenetic analyses of the ORF5 gene of acute porcine reproductive and respiratory syndrome virus isolates

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Development of a heteroduplex mobility assay to identify field isolates of porcine reproductive and respiratory syndrome virus with nucleotide sequences closely related to those of modified live-attenuated vaccines

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Expression and stability of foreign tags inserted into nsp2 of porcine reproductive and respiratory syndrome virus (PRRSV).

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Insertion and deletion in a non-essential region of the nonstructural protein 2 (nsp2) of porcine reproductive and respiratory syndrome (PRRS) virus: effects on virulence and immunogenicity.

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Challenges for porcine reproductive and respiratory syndrome virus (PRRSV) vaccinology

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Infectious clone-derived viruses from virulent and vaccine strains of porcine reproductive and respiratory syndrome virus mimic biological properties of their parental viruses in a pregnant sow model.

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Identification of virulence determinants of porcine reproductive and respiratory syndrome virus through construction of chimeric clones

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Impact of genetic diversity of European-type porcine reproductive and respiratory syndrome virus strains on vaccine efficacy

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A DNA-launched reverse genetics system for porcine reproductive and respiratory syndrome virus reveals that homodimerization of the nucleocapsid protein is essential for virus infectivity

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Modulation of dendritic cell function by persistent viruses.

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Role of neutralizing antibodies in PRRSV protective immunity

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Differential type I interferon activation and susceptibility of dendritic cell populations to porcine arterivirus

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Interleukin-8, interleukin-1beta, and interferon-gamma levels are linked to PRRS virus clearance.

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An infectious cDNA clone of a highly pathogenic porcine reproductive and respiratory syndrome virus variant associated with porcine high fever syndrome

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Suppression of lipopolysaccharide-induced antiviral transcription factor (STAT-1 and NF-kappa B) complexes by antibody-dependent enhancement of macrophage infection by Ross River virus

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The challenge of PRRS immunology.

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Targeting the porcine immune system--particulate vaccines in the 21st century

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Molecular cloning and nucleotide sequencing of the 3'-terminal genomic RNA of the porcine reproductive and respiratory syndrome virus

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Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe

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A nested set of six or seven subgenomic mRNAs is formed in cells infected with different isolates of porcine reproductive and respiratory syndrome virus

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Heterogeneity of porcine reproductive and respiratory syndrome virus: implications for current vaccine efficacy and future vaccine development

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PRRSV, the virus

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Molecular characterization of Lelystad virus.

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Characterization of proteins encoded by ORFs 2 to 7 of Lelystad virus.

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Immunological responses of swine to porcine reproductive and respiratory syndrome virus infection

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Assessment of the economic impact of porcine reproductive and respiratory syndrome on swine production in the United States

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Langerhans cells in porcine skin

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Generation of an infectious clone of VR-2332, a highly virulent North American-type isolate of porcine reproductive and respiratory syndrome virus

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Epitope mapping porcine reproductive and respiratory syndrome virus by phage display: the nsp2 fragment of the replicase polyprotein contains a cluster of B-cell epitopes

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Comparison of molecular and biological characteristics of a modified live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine (ingelvac PRRS MLV), the parent strain of the vaccine (ATCC VR2332), ATCC VR2385, and two recent field isol

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Transmissible gastroenteritis coronavirus gene 7 is not essential but influences in vivo virus replication and virulence.

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Passive transfer of virus-specific antibodies confers protection against reproductive failure induced by a virulent strain of porcine reproductive and respiratory syndrome virus and establishes sterilizing immunity

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Identification of neutralizing and nonneutralizing epitopes in the porcine reproductive and respiratory syndrome virus GP5 ectodomain.

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Dendritic cells: a link between innate and adaptive immunity

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Monoclonal antibodies to the ORF5 product of porcine reproductive and respiratory syndrome virus define linear neutralizing determinants

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GP5 ectodomain epitope of porcine reproductive and respiratory syndrome virus, strain Lelystad virus

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The primary GP5 neutralization epitope of North American isolates of porcine reproductive and respiratory syndrome virus

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7 January 2021

The primary neutralization epitope of porcine respiratory and reproductive syndrome virus strain VR-2332 is located in the middle of the GP5 ectodomain

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Targeting to porcine sialoadhesin receptor improves antigen presentation to T cells.

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Attenuated influenza virus vaccines with modified NS1 proteins

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Characterization of emerging European-like porcine reproductive and respiratory syndrome virus isolates in the United States

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The stealthy nature of PRRSV infection: the dangers posed by that ever-changing mystery swine disease

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Deciphering the involvement of innate immune factors in the development of the host response to PRRSV vaccination.

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Regulatory T cells: how do they suppress immune responses?

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Toll-like receptor 3 activation decreases porcine arterivirus infection.

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Immune responses of pigs inoculated with a recombinant fowlpox virus coexpressing GP5/GP3 of porcine reproductive and respiratory syndrome virus and swine IL-18.

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7 January 2021

Experimental infection of maternally immune pigs with porcine reproductive and respiratory syndrome (PRRS) virus

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7 January 2021

European genotype of porcine reproductive and respiratory syndrome (PRRSV) infects monocyte-derived dendritic cells but does not induce Treg cells

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Induction of T helper 3 regulatory cells by dendritic cells infected with porcine reproductive and respiratory syndrome virus

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7 January 2021

The molecular biology of arteriviruses

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Cryo-electron tomography of porcine reproductive and respiratory syndrome virus: organization of the nucleocapsid

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7 January 2021

Porcine reproductive and respiratory syndrome virus strains of exceptional diversity in eastern Europe support the definition of new genetic subtypes.

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7 January 2021

Taking dendritic cells into medicine

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IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection

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Examination of the selective pressures on a live PRRS vaccine virus

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Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody.

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7 January 2021

Increased production of proinflammatory cytokines following infection with porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae

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Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmark

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7 January 2021

Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

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7 January 2021

Antibody-Dependent Enhancement of Virus Infection and Disease

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CD4+ CD25+ T cells regulate vaccine-generated primary and memory CD8+ T-cell responses against herpes simplex virus type 1.

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7 January 2021

A highly pathogenic porcine reproductive and respiratory syndrome virus generated from an infectious cDNA clone retains the in vivo virulence and transmissibility properties of the parental virus.

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7 January 2021

The M/GP(5) glycoprotein complex of porcine reproductive and respiratory syndrome virus binds the sialoadhesin receptor in a sialic acid-dependent manner

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Sialoadhesin and CD163 join forces during entry of the porcine reproductive and respiratory syndrome virus

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7 January 2021

DC-SIGN: escape mechanism for pathogens

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7 January 2021

Involvement of sialoadhesin in entry of porcine reproductive and respiratory syndrome virus into porcine alveolar macrophages

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Porcine reproductive and respiratory syndrome virus productively infects monocyte-derived dendritic cells and compromises their antigen-presenting ability

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Attenuation of porcine reproductive and respiratory syndrome virus strain MN184 using chimeric construction with vaccine sequence

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Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain

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Mystery swine disease in the Netherlands: The isolation of Lelystad virus

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Envelope protein requirements for the assembly of infectious virions of porcine reproductive and respiratory syndrome virus

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Induction of inducible CD4+CD25+Foxp3+ regulatory T lymphocytes by porcine reproductive and respiratory syndrome virus (PRRSV).

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Dendritic-cell interactions with HIV: infection and viral dissemination

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Categorization of North American porcine reproductive and respiratory syndrome viruses: epitopic profiles of the N, M, GP5 and GP3 proteins and susceptibility to neutralization

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Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and their potential as vaccine vectors

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Antibody-dependent enhancement (ADE) of porcine reproductive and respiratory syndrome virus (PRRSV) infection in pigs

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7 January 2021

Field isolates of porcine reproductive and respiratory syndrome virus (PRRSV) vary in their susceptibility to antibody dependent enhancement (ADE) of infection

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.07.020

7 January 2021

The 30-amino-acid deletion in the Nsp2 of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China is not related to its virulence.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.07.020

7 January 2021

Virus-encoded proteinases and proteolytic processing in the Nidovirales.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.07.020

7 January 2021

Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.07.020

7 January 2021

Processing and evolution of the N-terminal region of the arterivirus replicase ORF1a protein: identification of two papainlike cysteine proteases

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.07.020

7 January 2021

based on heuristic

inferred from DOI database lookup

Infectious transcripts from cloned genome-length cDNA of porcine reproductive and respiratory syndrome virus.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.07.020

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma- induced genes by suppressing tyrosine phosphorylation of STAT1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20655962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical consequences of exposing pregnant gilts to strains of porcine reproductive and respiratory syndrome (PRRS) virus isolated from field cases of "atypical" PRRS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20655962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the cytokine and maturation responses of pure populations of porcine plasmacytoid dendritic cells to porcine viruses and toll-like receptor agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/20655962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Porcine reproductive and respiratory syndrome virus comparison: divergent evolution on two continents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20655962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis of porcine reproductive and respiratory syndrome virus infection in mid-gestation sows and fetuses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20655962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.VIRUSRES.2010.07.020

1 reference

Europe PubMed Central

23 August 2017

0 references

1 reference

Europe PubMed Central

23 August 2017

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