(Q37776219)

23 August 2017

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title

Nanoimaging for protein misfolding diseases (English)

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23 August 2017

Yuri L Lyubchenko

1

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23 August 2017

Bo-Hyun Kim

series ordinal

2

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23 August 2017

Alexey V Krasnoslobodtsev

series ordinal

3

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23 August 2017

Junping Yu

series ordinal

4

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23 August 2017

publication date

1 September 2010

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Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

23 August 2017

published in

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23 August 2017

volume

2

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23 August 2017

issue

5

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23 August 2017

page(s)

526-543

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Principles of protein folding, misfolding and aggregation

23 August 2017

cites work

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Structural insights into the polymorphism of amyloid-like fibrils formed by region 20-29 of amylin revealed by solid-state NMR and X-ray fiber diffraction

21 January 2018

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Comparison of Alzheimer Abeta(1-40) and Abeta(1-42) amyloid fibrils reveals similar protofilament structures

21 January 2018

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Structure-neurotoxicity relationships of amyloid beta-protein oligomers

21 January 2018

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Nanoimaging for protein misfolding and related diseases

21 January 2018

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Recent structural and computational insights into conformational diseases

21 January 2018

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Fluorescence as a method to reveal structures and membrane-interactions of amyloidogenic proteins

21 January 2018

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Amyloid fibers are water-filled nanotubes

21 January 2018

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Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid beta-peptide of amyloid plaques.

21 January 2018

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Atomic structures of amyloid cross-beta spines reveal varied steric zippers

21 January 2018

1 reference

Review: model peptides and the physicochemical approach to beta-amyloids

21 January 2018

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A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

21 January 2018

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Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance

21 January 2018

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Solid state NMR reveals a pH-dependent antiparallel beta-sheet registry in fibrils formed by a beta-amyloid peptide

21 January 2018

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Characterization of beta-sheet structure in Ure2p1-89 yeast prion fibrils by solid-state nuclear magnetic resonance

21 January 2018

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Parallel beta-sheets and polar zippers in amyloid fibrils formed by residues 10-39 of the yeast prion protein Ure2p

21 January 2018

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Amyloid of the prion domain of Sup35p has an in-register parallel beta-sheet structure

21 January 2018

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Amyloid of Rnq1p, the basis of the [PIN+] prion, has a parallel in-register beta-sheet structure

21 January 2018

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Structural disorder in amyloid fibrils: its implication in dynamic interactions of proteins

21 January 2018

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Role of intermolecular forces in defining material properties of protein nanofibrils

21 January 2018

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Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

21 January 2018

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Kinetics and Mechanism of Deoxyhemoglobin S Gelation: A New Approach to Understanding Sickle Cell Disease

21 January 2018

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Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

21 January 2018

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Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

21 January 2018

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Analysis of protein aggregation kinetics.

21 January 2018

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Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation

21 January 2018

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Model discrimination and mechanistic interpretation of kinetic data in protein aggregation studies

21 January 2018

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Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease

21 January 2018

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Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

21 January 2018

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Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

21 January 2018

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Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

21 January 2018

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Rapid photochemical cross-linking--a new tool for studies of metastable, amyloidogenic protein assemblies

21 January 2018

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Amyloid beta-protein assembly and Alzheimer disease

21 January 2018

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Role of small oligomers on the amyloidogenic aggregation free-energy landscape

21 January 2018

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Mechanical design of proteins studied by single-molecule force spectroscopy and protein engineering.

21 January 2018

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Observing single biomolecules at work with the atomic force microscope.

21 January 2018

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Stretching single molecules into novel conformations using the atomic force microscope.

21 January 2018

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Atomic force microscopy and proteins

21 January 2018

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Atomic force microscopy imaging and pulling of nucleic acids

21 January 2018

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Nanoscale exploration of microbial surfaces using the atomic force microscope

21 January 2018

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Detection and localization of single molecular recognition events using atomic force microscopy

21 January 2018

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Probing DNA-peptide interaction forces at the single-molecule level.

21 January 2018

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Atomic force microscopy of microbial cells: application to nanomechanical properties, surface forces and molecular recognition forces.

21 January 2018

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Interrogation of single synthetic polymer chains and polysaccharides by AFM-based force spectroscopy

21 January 2018

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Reviewing biophysical and cell biological methodologies in cell-penetrating peptide (CPP) research

21 January 2018

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Atomic force microscopy to study interacting forces in phospholipid bilayers containing general anesthetics

21 January 2018

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Towards nanomicrobiology using atomic force microscopy.

21 January 2018

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Structure and mechanics of membrane proteins

21 January 2018

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Single-cell force spectroscopy

21 January 2018

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AFM: a nanotool in membrane biology

21 January 2018

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Atomic force microscopy of biological membranes

21 January 2018

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Force and function: probing proteins with AFM-based force spectroscopy.

21 January 2018

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Atomic force microscopy imaging and probing of DNA, proteins, and protein DNA complexes: silatrane surface chemistry

21 January 2018

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Probing the relation between force--lifetime--and chemistry in single molecular bonds

21 January 2018

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Models for the Specific Adhesion of Cells to Cells

21 January 2018

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Forces and bond dynamics in cell adhesion.

21 January 2018

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Probing Interactions within the synaptic DNA-SfiI complex by AFM force spectroscopy

21 January 2018

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Nanomedicine and protein misfolding diseases.

21 January 2018

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Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

21 January 2018

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Alpha-synuclein in Lewy bodies

21 January 2018

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 January 2018

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 January 2018

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 January 2018

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A Drosophila model of Parkinson's disease

21 January 2018

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Alpha-synuclein misfolding and neurodegenerative diseases

21 January 2018

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Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling

21 January 2018

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A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

21 January 2018

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Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR.

21 January 2018

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Evidence for a partially folded intermediate in alpha-synuclein fibril formation

21 January 2018

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Nanotools for megaproblems: probing protein misfolding diseases using nanomedicine modus operandi

21 January 2018

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The aggregation and fibrillation of alpha-synuclein

21 January 2018

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Biophysics of Parkinson's disease: structure and aggregation of alpha-synuclein

21 January 2018

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Dynamics of alpha-synuclein aggregation and inhibition of pore-like oligomer development by beta-synuclein

21 January 2018

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Mechanism of alpha-synuclein oligomerization and membrane interaction: theoretical approach to unstructured proteins studies

21 January 2018

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Real-time analysis of amyloid fibril formation of alpha-synuclein using a fibrillation-state-specific fluorescent probe of JC-1.

21 January 2018

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Direct observation of amyloid fibril growth monitored by thioflavin T fluorescence

21 January 2018

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Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein

21 January 2018

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alpha-Synuclein misfolding: single molecule AFM force spectroscopy study

21 January 2018

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Exploring the energy landscape of GFP by single-molecule mechanical experiments

21 January 2018

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Protein structure by mechanical triangulation

21 January 2018

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A general model of prion strains and their pathogenicity

21 January 2018

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The most infectious prion protein particles.

21 January 2018

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Dynamic properties of pH-dependent structural organization of the amyloidogenic beta-protein (1-40).

21 January 2018

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Amyloid formation from HypF-N under conditions in which the protein is initially in its native state

21 January 2018

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Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers

21 January 2018

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Conformational equilibria in monomeric alpha-synuclein at the single-molecule level

21 January 2018

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An amyloid-forming peptide from the yeast prion Sup35 reveals a dehydrated beta-sheet structure for amyloid

21 January 2018

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

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Soluble amyloid-beta peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo.

21 January 2018

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Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide

21 January 2018

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Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils

21 January 2018

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Amyloid-beta(1-42) rapidly forms protofibrils and oligomers by distinct pathways in low concentrations of sodium dodecylsulfate

21 January 2018

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The Alzheimer's peptides Abeta40 and 42 adopt distinct conformations in water: a combined MD / NMR study

21 January 2018

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Observation of multi-step conformation switching in beta-amyloid peptide aggregation by fluorescence resonance energy transfer

21 January 2018

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Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

21 January 2018

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Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid.

21 January 2018

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A Lumry-Eyring nucleated polymerization model of protein aggregation kinetics: 1. Aggregation with pre-equilibrated unfolding.

21 January 2018

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Direct characterization of amyloidogenic oligomers by single-molecule fluorescence

21 January 2018

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Nucleated conformational conversion and the replication of conformational information by a prion determinant

21 January 2018

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The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid

21 January 2018

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Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes

21 January 2018

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Amyloid beta protein forms ion channels: implications for Alzheimer's disease pathophysiology

21 January 2018

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Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels

21 January 2018

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Models of toxic beta-sheet channels of protegrin-1 suggest a common subunit organization motif shared with toxic alzheimer beta-amyloid ion channels

21 January 2018

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Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm

21 January 2018

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Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome

21 January 2018

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Principles of Fluorescence Spectroscopy

21 January 2018

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Dehydration stability of amyloid fibrils studied by AFM

21 January 2018

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Energy landscapes of receptor-ligand bonds explored with dynamic force spectroscopy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/WNAN.102

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23 August 2017

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