(Q37780711)

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10 February 2020

title

T-cell recognition of chemicals, protein allergens and drugs: towards the development of in vitro assays (English)

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10 February 2020

2

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10 February 2020

Sonja Schmucker

3

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10 February 2020

Marc Vocanson

7

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10 February 2020

Jean Francois Nicolas

8

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10 February 2020

Werner J. Pichler

10

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10 February 2020

19

Federica Sallusto

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10 February 2020

author name string

Stefan F Martin

1

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10 February 2020

Lisa Dietz

4

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10 February 2020

Dean J Naisbitt

5

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10 February 2020

B Kevin Park

6

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10 February 2020

Monika Keller

9

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10 February 2020

Matthias Peiser

11

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10 February 2020

Andreas Luch

12

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10 February 2020

Reinhard Wanner

13

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10 February 2020

Enrico Maggi

14

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10 February 2020

Andrea Cavani

15

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10 February 2020

Thomas Rustemeyer

16

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10 February 2020

Anne Richter

17

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10 February 2020

Hermann-Josef Thierse

18

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10 February 2020

publication date

18 August 2010

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10 February 2020

number of pages

14

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Cellular and Molecular Life Sciences

inferred from page(s)

published in

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10 February 2020

volume

67

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10 February 2020

issue

24

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10 February 2020

page(s)

4171-4184

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Metal-protein complex-mediated transport and delivery of Ni2+ to TCR/MHC contact sites in nickel-specific human T cell activation

10 February 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-010-0495-3

Peptide-conjugated hapten groups are the major antigenic determinants for trinitrophenyl-specific cytotoxic T cells

21 January 2018

1 reference

12 December 2020

Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity

1 reference

12 December 2020

Toxicology. Transforming environmental health protection

1 reference

12 December 2020

Anti-inflammatory and immune-regulatory mechanisms prevent contact hypersensitivity to Arnica montana L.

1 reference

12 December 2020

Quantitative DY-maleimide-based proteomic 2-DE-labeling strategies using human skin proteins

1 reference

12 December 2020

Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods.

1 reference

12 December 2020

Skin sensitizers induce antioxidant response element dependent genes: application to the in vitro testing of the sensitization potential of chemicals

1 reference

12 December 2020

Structural complexity of antigenic determinants for class I MHC-restricted, hapten-specific T cells. Two qualitatively differing types of H-2Kb-restricted TNP epitopes

1 reference

12 December 2020

Chemical reactivity measurement and the predicitve identification of skin sensitisers. The report and recommendations of ECVAM Workshop 64.

1 reference

12 December 2020

Progress on the development of human in vitro dendritic cell based assays for assessment of the sensitizing potential of a compound

1 reference

12 December 2020

Chemical regulators have overreached

1 reference

12 December 2020

Role of hapten-anchoring peptides in defining hapten-epitopes for MHC-restricted cytotoxic T cells. Cross-reactive TNP-determinants on different peptides

1 reference

12 December 2020

Components of the ligand for a Ni++ reactive human T cell clone

1 reference

12 December 2020

Synthetic peptides anchor T cell-specific TNP epitopes to MHC antigens

1 reference

12 December 2020

Investigating protein haptenation mechanisms of skin sensitisers using human serum albumin as a model protein

1 reference

12 December 2020

Penicilloyl peptides are recognized as T cell antigenic determinants in penicillin allergy

1 reference

12 December 2020

A future approach to measuring relative skin sensitising potency: a proposal

1 reference

12 December 2020

A new dendritic cell type suitable as sentinel of contact allergens

1 reference

12 December 2020

Re-evaluation of animal numbers and costs for in vivo tests to accomplish REACH legislation requirements for chemicals - a report by the transatlantic think tank for toxicology (t(4)).

1 reference

12 December 2020

Delayed drug hypersensitivity reactions - new concepts

1 reference

12 December 2020

Direct access to CD4+ T cells specific for defined antigens according to CD154 expression.

1 reference

12 December 2020

Skin exposure to weak and moderate contact allergens induces IFNgamma production by lymph node cells of CD4+ T-cell-depleted mice

1 reference

12 December 2020

Reactivity profiling: covalent modification of single nucleophile peptides for skin sensitization risk assessment.

1 reference

12 December 2020

Subproteomic analysis of metal-interacting proteins in human B cells

1 reference

12 December 2020

Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones

1 reference

12 December 2020

Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells

1 reference

12 December 2020

Nothing is perfect, not even the local lymph node assay: a commentary and the implications for REACH.

1 reference

12 December 2020

Medical genetics: a marker for Stevens-Johnson syndrome

1 reference

12 December 2020

Depletion of human peripheral blood lymphocytes in CD25+ cells allows for the sensitive in vitro screening of contact allergens

1 reference

12 December 2020

Local lymph node data for the evaluation of skin sensitization alternatives: a second compilation.

1 reference

12 December 2020

Human naive and memory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells

1 reference

12 December 2020

Heterogeneous T cell responses to beta-lactam-modified self-structures are observed in penicillin-allergic individuals.

1 reference

12 December 2020

Identification of gene expression changes induced by chemical allergens in dendritic cells: opportunities for skin sensitization testing

1 reference

12 December 2020

Evaluation of the capacity of dendritic cells derived from cord blood CD34+ precursors to present haptens to unsensitized autologous T cells in vitro

1 reference

12 December 2020

Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities

1 reference

12 December 2020

Animal testing and alternative approaches for the human health risk assessment under the proposed new European chemicals regulation

1 reference

12 December 2020

Endocytosis mechanisms and the cell biology of antigen presentation

1 reference

12 December 2020

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

1 reference

12 December 2020

Clinical implications of in vitro drug-induced interferon gamma release from peripheral blood lymphocytes in cutaneous adverse drug reactions

1 reference

12 December 2020

In vitro human T cell sensitization to haptens by monocyte-derived dendritic cells

1 reference

12 December 2020

From innate to adaptive immune responses in contact hypersensitivity

1 reference

12 December 2020

Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens.

1 reference

12 December 2020

In vitro primary sensitization and restimulation of hapten-specific T cells by fresh and cultured human epidermal Langerhans' cells.

1 reference

12 December 2020

Stimulation of human T cells with sulfonamides and sulfonamide metabolites.

1 reference

12 December 2020

Interaction of sulfonamide derivatives with the TCR of sulfamethoxazole-specific human alpha beta+ T cell clones.

1 reference

12 December 2020

Streamlined chemical tests rebuffed

1 reference

12 December 2020

Naïve, hapten-specific human T lymphocytes are primed in vitro with derivatized blood mononuclear cells

1 reference

12 December 2020

Drug-specific in vitro release of IL-2, IL-5, IL-13 and IFN-gamma in patients with delayed-type drug hypersensitivity.

1 reference

12 December 2020

In vitro evaluation of the sensitization potential of weak contact allergens using langerhans-like dendritic cells and autologous T cells

1 reference

12 December 2020

Gene expression changes in peripheral blood-derived dendritic cells following exposure to a contact allergen

1 reference

12 December 2020

Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir

1 reference

12 December 2020

Classification of sensitizing and irritative potential in a combined in-vitro assay

1 reference

12 December 2020

Updating the skin sensitization in vitro data assessment paradigm in 2009.

1 reference

12 December 2020

Allergic contact dermatitis--formation, structural requirements, and reactivity of skin sensitizers

1 reference

12 December 2020

European "REACH" (Registration, Evaluation, Authorisation and Restriction of Chemicals) program

1 reference

12 December 2020

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro.

1 reference

12 December 2020

Determination of interleukin-5 secretion from drug-specific activated ex vivo peripheral blood mononuclear cells as a test system for the in vitro detection of drug sensitization

1 reference

12 December 2020

Characterization of p-phenylenediamine-albumin binding sites and T-cell responses to hapten-modified protein

1 reference

12 December 2020

Rapid identification and sorting of viable virus-reactive CD4(+) and CD8(+) T cells based on antigen-triggered CD137 expression

1 reference

12 December 2020

HLA-restricted, processing- and metabolism-independent pathway of drug recognition by human alpha beta T lymphocytes.

1 reference

12 December 2020

Interactions of chemicals and metal ions with proteins and role for immune responses

1 reference

12 December 2020

A new type of metal recognition by human T cells: contact residues for peptide-independent bridging of T cell receptor and major histocompatibility complex by nickel

1 reference

12 December 2020

CD69 upregulation on T cells as an in vitro marker for delayed-type drug hypersensitivity

1 reference

12 December 2020

Human T lymphocyte priming in vitro by haptenated autologous dendritic cells

1 reference

12 December 2020

Multiple adduction reactions of nitroso sulfamethoxazole with cysteinyl residues of peptides and proteins: implications for hapten formation

1 reference

12 December 2020

Cross-reactive trinitrophenylated peptides as antigens for class II major histocompatibility complex-restricted T cells and inducers of contact sensitivity in mice. Limited T cell receptor repertoire

1 reference

12 December 2020

In vitro primary sensitization of hapten-specific T cells by cultured human epidermal Langerhans cells--a screening predictive assay for contact sensitizers

1 reference

12 December 2020

CD8+ T cells are effector cells of contact dermatitis to common skin allergens in mice.

1 reference

12 December 2020

Innate and adaptive immune responses in contact dermatitis: analogy with infections.

1 reference

12 December 2020

Allele-unrestricted presentation of lidocaine by HLA-DR molecules to specific alphabeta+ T cell clones

1 reference

12 December 2020

Improved detection of allergen-specific T-cell responses in allergic contact dermatitis through the addition of 'cytokine cocktails'.

1 reference

12 December 2020

T lymphocyte-mediated immune responses to chemical haptens and metal ions: implications for allergic and autoimmune disease

1 reference

12 December 2020

Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity

1 reference

12 December 2020

Quantification of chemical peptide reactivity for screening contact allergens: a classification tree model approach

1 reference

12 December 2020

Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?

1 reference

12 December 2020

Skin: major target organ of allergic reactions to small molecular weight compounds

1 reference

12 December 2020

"MIATA"-minimal information about T cell assays

1 reference

12 December 2020

T cell receptor (TCR) interaction with haptens: metal ions as non-classical haptens

1 reference

12 December 2020

A loose-fit coculture of activated keratinocytes and dendritic cell-related cells for prediction of sensitizing potential

1 reference

12 December 2020

Tracking human contact allergens: from mass spectrometric identification of peptide-bound reactive small chemicals to chemical-specific naive human T-cell priming

1 reference

12 December 2020

Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSA in vitro and in vivo.

1 reference

12 December 2020

10.1007/S00018-010-0495-3

Identifiers

DOI

1 reference

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10 February 2020

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