(Q37782273)

23 August 2017

title

Anti-inflammatory treatment of uveitis with biologicals: new treatment options that reflect pathogenetic knowledge of the disease (English)

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23 August 2017

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1 reference

Arnd Heiligenhaus

1

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23 August 2017

Stephan Thurau

2

1 reference

23 August 2017

Maren Hennig

3

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23 August 2017

Rafael S Grajewski

4

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23 August 2017

Gerhild Wildner

5

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23 August 2017

publication date

25 August 2010

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Graefe's Archive for Clinical and Experimental Ophthalmology

23 August 2017

published in

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23 August 2017

volume

248

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23 August 2017

issue

11

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23 August 2017

page(s)

1531-1551

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https://scigraph.springernature.com/pub.10.1007/s00417-010-1485-8

23 August 2017

exact match

0 references

cites work

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Resistant Behçet disease responsive to anakinra

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Interferon-alpha in the management of patients with Behçet's disease.

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Intermediate uveitis: long-term course and visual outcome

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Involvement of Th17 cells and the effect of anti-IL-6 therapy in autoimmune uveitis

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Transgenic expression of an immunologically privileged retinal antigen extraocularly enhances self tolerance and abrogates susceptibility to autoimmune uveitis

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Comparison of clinical and experimental uveitis

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Review: anti-CTLA-4 antibody ipilimumab: case studies of clinical response and immune-related adverse events

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Role of cytokines in rheumatoid arthritis

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Do TNF-blockers reduce or induce uveitis?

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Recruitment of antigen-nonspecific cells plays a pivotal role in the pathogenesis of a T cell-mediated organ-specific autoimmune disease, experimental autoimmune uveoretinitis

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Treatment of acute uveitis associated with Crohn's disease and sacroileitis with infliximab

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Loss of efficacy during long-term infliximab therapy for sight-threatening childhood uveitis.

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12 December 2020

Daclizumab for treatment of birdshot chorioretinopathy

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12 December 2020

Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases

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12 December 2020

Long-term outcome of etanercept therapy in children with treatment-refractory uveitis

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12 December 2020

Progress in antisense technology.

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12 December 2020

Treatment of primary Sjogren syndrome with rituximab: extended follow-up, safety and efficacy of retreatment

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12 December 2020

The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial

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12 December 2020

Lineage commitment in the immune system: the T helper lymphocyte grows up.

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12 December 2020

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12 December 2020

Treatment of noninfectious intermediate and posterior uveitis with the humanized anti-Tac mAb: a phase I/II clinical trial

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12 December 2020

Clinical value of blocking IL-6 receptor

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12 December 2020

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12 December 2020

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12 December 2020

TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1.

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12 December 2020

Successful treatment of Wegener's granulomatosis associated scleritis with rituximab

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12 December 2020

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

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12 December 2020

Elevated levels of interleukin 6 in the vitreous fluid of patients with pars planitis and posterior uveitis: the Massachusetts eye & ear experience and review of previous studies

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12 December 2020

Decreased incidence of anterior uveitis in patients with ankylosing spondylitis treated with the anti-tumor necrosis factor agents infliximab and etanercept

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12 December 2020

T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat

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12 December 2020

Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis

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12 December 2020

Interleukin-8, interleukin-10, intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expression levels are higher in synovial tissue from patients with rheumatoid arthritis than in osteoarthritis

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12 December 2020

Kinetics of intraocular tumor necrosis factor and interleukin-6 in endotoxin-induced uveitis in the rat.

1 reference

12 December 2020

Anti-TNF-alpha therapy in patients with chronic non-infectious uveitis: the experience of Jules Gonin Eye Hospital

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12 December 2020

Interleukin 6 as a therapeutic target in systemic-onset juvenile idiopathic arthritis

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12 December 2020

The TNF-TNF receptor system

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12 December 2020

T cell activation in rheumatoid synovium is B cell dependent

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12 December 2020

B cell therapy for rheumatoid arthritis: the rituximab (anti-CD20) experience

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12 December 2020

Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs

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12 December 2020

A randomized, placebo-controlled, double-masked clinical trial of etanercept for the treatment of uveitis associated with juvenile idiopathic arthritis

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Adhesion molecules in iris biopsy specimens from patients with uveitis

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Cutting edge: in vivo blockade of human IL-2 receptor induces expansion of CD56(bright) regulatory NK cells in patients with active uveitis

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12 December 2020

Infliximab in the treatment of refractory posterior uveitis

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12 December 2020

Long-term efficacy and safety of low-dose interferon alpha2a therapy in severe uveitis associated with Behçet disease

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12 December 2020

Reduction of fatigue in Sjögren syndrome with rituximab: results of a randomised, double-blind, placebo-controlled pilot study.

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12 December 2020

Anti-TNF-alpha therapy in seven patients with Behcet's uveitis: advantages and controversial aspects

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12 December 2020

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

1 reference

12 December 2020

Anti-TNF-alpha therapies: the next generation

1 reference

12 December 2020

An evaluation of ocular inflammation following the injection of bacterial endotoxin into the rat foot pad

1 reference

12 December 2020

Cytokine profile in Behçet's disease patients. Relationship with disease activity

1 reference

12 December 2020

Tailoring biological treatment: anakinra treatment of posterior uveitis associated with the CINCA syndrome.

1 reference

12 December 2020

Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells

1 reference

12 December 2020

Long-term observation of patients with anti-neutrophil cytoplasmic antibody-associated vasculitis treated with rituximab

1 reference

12 December 2020

The recombinant humanized anti-IL-6 receptor antibody tocilizumab, an innovative drug for the treatment of rheumatoid arthritis

1 reference

12 December 2020

Cytokines and autoimmunity

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12 December 2020

Benefit-risk assessment of infliximab in the treatment of rheumatoid arthritis

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12 December 2020

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

1 reference

12 December 2020

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Monoclonal Antibodies against ICAM-1 (CD54) and LFA-1 (CD11a/CD18) Inhibit Experimental Autoimmune Uveitis

1 reference

12 December 2020

Correlation of metalloproteinase-2 and -9 with proinflammatory cytokines interleukin-1b, interleukin-12 and the interleukin-1 receptor antagonist in patients with chronic uveitis

1 reference

12 December 2020

Adalimumab in the therapy of uveitis in childhood

1 reference

12 December 2020

Infliximab effects compared to conventional therapy in the management of retinal vasculitis in Behçet disease

1 reference

12 December 2020

A double-masked, randomized study to investigate the safety and efficacy of daclizumab to treat the ocular complications related to Behçet's disease

1 reference

12 December 2020

Rituximab as rescue therapy in anti-neutrophil cytoplasmic antibody-associated vasculitis: a single-centre experience with 15 patients

1 reference

12 December 2020

Infliximab and etanercept in the treatment of chronic uveitis associated with refractory juvenile idiopathic arthritis

1 reference

12 December 2020

Spotlight on alemtuzumab.

1 reference

12 December 2020

Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks

1 reference

12 December 2020

Endotoxin-induced uveitis (EIU) in the rat: A study of inflammatory and immunological mechanisms

1 reference

12 December 2020

Remission induction in Behçet's disease following lymphocyte depletion by the anti-CD52 antibody CAMPATH 1-H.

1 reference

12 December 2020

Retrobulbar optic neuritis associated with infliximab.

1 reference

12 December 2020

Efficacy of tumour necrosis factor blockers in reducing uveitis flares in patients with spondylarthropathy: a retrospective study

1 reference

12 December 2020

Repeated B cell depletion in treatment of refractory systemic lupus erythematosus

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12 December 2020

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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12 December 2020

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

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12 December 2020

IL-6 in autoimmune disease and chronic inflammatory proliferative disease

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12 December 2020

Immunological and virological predictors of outcome during interferon-alpha therapy of chronic hepatitis C.

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12 December 2020

Degree, duration, and causes of visual loss in uveitis.

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12 December 2020

Autoimmune uveitis induced by molecular mimicry of peptides from rotavirus, bovine casein and retinal S-antigen

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12 December 2020

Endotoxin-induced uveitis in rats as a model for human disease

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12 December 2020

Biological response modifier therapy for refractory childhood uveitis

1 reference

12 December 2020

Blood serum interleukin-1 receptor antagonist in pars planitis and ocular Behçet disease

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12 December 2020

Macrophages and dendritic cells in IRBP-induced experimental autoimmune uveoretinitis in B10RIII mice

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12 December 2020

TNF neutralization in MS: results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group

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12 December 2020

Immunological and inflammatory functions of the interleukin-1 family

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12 December 2020

Natalizumab in the treatment of Crohn's disease.

1 reference

12 December 2020

Side effects of high-dose interferon therapy for chronic hepatitis C.

1 reference

12 December 2020

Analysis of interleukin-6 in endotoxin-induced uveitis.

1 reference

12 December 2020

Rapid responses to anakinra in patients with refractory adult-onset Still's disease

1 reference

12 December 2020

IL-6 antagonizes TGF-beta and abolishes immune privilege in eyes with endotoxin-induced uveitis.

1 reference

12 December 2020

Successful treatment of refractory anterior scleritis in primary Sjogren's syndrome with rituximab

1 reference

12 December 2020

Differential effectiveness of etanercept and infliximab in the treatment of ocular inflammation

1 reference

12 December 2020

A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis

1 reference

12 December 2020

Rituximab as a treatment option for refractory endogenous anterior uveitis

1 reference

12 December 2020

Cell fate decision: T-helper 1 and 2 subsets in immune responses

1 reference

12 December 2020

Low-dose subcutaneous alemtuzumab in refractory chronic lymphocytic leukaemia (CLL): results of a prospective, single-arm multicentre study.

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12 December 2020

The regulatory role of Valpha14 NKT cells in innate and acquired immune response.

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12 December 2020

Regulatory T cells are reduced during anti-CD25 antibody treatment of multiple sclerosis.

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12 December 2020

The role of B cells in rheumatoid arthritis: mechanisms and therapeutic targets

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12 December 2020

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

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12 December 2020

Interleukin 6: from bench to bedside

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12 December 2020

Balancing autoaggressive and protective T cell responses

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12 December 2020

Inhibition of autoimmune uveitis by anti-CD4 antibody

1 reference

12 December 2020

Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

1 reference

12 December 2020

CRALBP is a highly prevalent autoantigen for human autoimmune uveitis

1 reference

12 December 2020

Long-term efficacy of infliximab in refractory posterior uveitis of Behcet's disease: a 24-month follow-up study

1 reference

12 December 2020

Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice.

1 reference

12 December 2020

Adalimumab in juvenile idiopathic arthritis-associated chronic anterior uveitis.

1 reference

12 December 2020

Serum cytokine profiles in Behçet's disease: Is there a role for IL-15 in pathogenesis?

1 reference

12 December 2020

Adalimumab effectively reduces the rate of anterior uveitis flares in patients with active ankylosing spondylitis: results of a prospective open-label study

1 reference

12 December 2020

Autostimulatory effects of IL-6 on excessive B cell differentiation in patients with systemic lupus erythematosus: analysis of IL-6 production and IL-6R expression

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12 December 2020

Transforming growth factor-beta induces development of the T(H)17 lineage

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12 December 2020

The roles of IL-17A in inflammatory immune responses and host defense against pathogens

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12 December 2020

High-dose daclizumab for the treatment of juvenile idiopathic arthritis-associated active anterior uveitis

1 reference

12 December 2020

Interferon-alpha: a key factor in autoimmune disease?

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12 December 2020

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

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12 December 2020

Efficacy of Etanercept in Preventing Relapse of Uveitis Controlled by Methotrexate

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12 December 2020

Birdshot chorioretinopathy: long-term manifestations and visual prognosis

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12 December 2020

Adoptive transfer of experimental autoimmune uveoretinitis in rats. Immunopathogenic mechanisms and histologic features

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12 December 2020

Do self-perpetuating B lymphocytes drive human autoimmune disease?

1 reference

12 December 2020

Interferon-alpha as an effective treatment for noninfectious posterior uveitis and panuveitis

1 reference

12 December 2020

Effects of interferon-alpha on rhesus monkeys: a nonhuman primate model of cytokine-induced depression

1 reference

12 December 2020

Abatacept for refractory juvenile idiopathic arthritis-associated uveitis- a case report

1 reference

12 December 2020

A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens

1 reference

12 December 2020

Humanized antibodies against the alpha-chain of the IL-2 receptor and against the beta-chain shared by the IL-2 and IL-15 receptors in a monkey uveitis model of autoimmune diseases

1 reference

12 December 2020

Rituximab for treatment of ocular inflammatory disease: a series of four cases.

1 reference

12 December 2020

Campath-1H therapy in refractory ocular inflammatory disease

1 reference

12 December 2020

Detection of a circulating form of vascular cell adhesion molecule-1: raised levels in rheumatoid arthritis and systemic lupus erythematosus

1 reference

12 December 2020

Sjögren keratoconjunctivitis sicca treated with rituximab.

1 reference

12 December 2020

Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade

1 reference

12 December 2020

Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial

1 reference

12 December 2020

Monoclonal antibodies against CD54 (ICAM-1) and CD11a (LFA-1) prevent and inhibit endotoxin-induced uveitis

1 reference

12 December 2020

Pathology of experimental autoimmune uveoretinitis in mice

1 reference

12 December 2020

Anti-tumor necrosis factor-alpha therapy with infliximab as an alternative to corticosteroids in the treatment of human leukocyte antigen B27-associated acute anterior uveitis

1 reference

12 December 2020

Does etanercept induce uveitis?

1 reference

12 December 2020

Efalizumab: an overview

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12 December 2020

Interferon Alpha Treatment and Thyroid Dysfunction

1 reference

12 December 2020

Constitutive expression of IL-6 receptors and their role in the excessive B cell function in patients with systemic lupus erythematosus

1 reference

12 December 2020

VLA-4 blockade suppresses endotoxin-induced uveitis: in vivo evidence for functional integrin up-regulation

1 reference

12 December 2020

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

1 reference

12 December 2020

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

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12 December 2020

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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12 December 2020

Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics

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12 December 2020

Clinical observations programme in SpA: disease parameters, treatment options and practical management issues

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12 December 2020

Taming TNF: strategies to restrain this proinflammatory cytokine

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12 December 2020

Efficacy of interferon alpha in the treatment of refractory and sight threatening uveitis: a retrospective monocentric study of 45 patients

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12 December 2020

Induction of arthritis and uveitis in Lewis rats by antigenic mimicry of peptides from HLA-B27 and cytokeratin

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12 December 2020

Rituximab is effective in the treatment of refractory ophthalmic Wegener's granulomatosis

1 reference

12 December 2020

Etanercept (enbrel)-associated inflammatory eye disease: case report and review of the literature

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12 December 2020

Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system

1 reference

12 December 2020

Infliximab treatment for ocular and extraocular manifestations of Behçet's disease

1 reference

12 December 2020

Th17 cells in human disease.

1 reference

12 December 2020

Efficacy and safety of the selective co-stimulation modulator abatacept following 2 years of treatment in patients with rheumatoid arthritis and an inadequate response to anti-tumour necrosis factor therapy.

1 reference

12 December 2020

Treatment of ocular inflammatory disorders with daclizumab

1 reference

12 December 2020

Safety and efficacy of infliximab therapy in active behcet's uveitis: an open-label trial

1 reference

12 December 2020

Treatment of refractory SLE with rituximab plus cyclophosphamide: clinical effects, serological changes, and predictors of response

1 reference

12 December 2020

Upregulated IL-23 and IL-17 in Behçet patients with active uveitis.

1 reference

12 December 2020

Intravenous daclizumab for recalcitrant ocular inflammatory disease

1 reference

12 December 2020

10.1007/S00417-010-1485-8

Identifiers

DOI

1 reference

23 August 2017

1 reference