(Q37784730)

23 August 2017

Application of method suitability for drug permeability classification (English)

1 reference

23 August 2017

Donna A Volpe

1

1 reference

PMCID

2976984

23 August 2017

language of work or name

English

0 references

publication date

2 September 2010

1 reference

23 August 2017

1 reference

23 August 2017

12

1 reference

23 August 2017

670-678

1 reference

23 August 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1208/s12248-010-9227-8

23 August 2017

0 references

cites work

Variability in Caco-2 and MDCK cell-based intestinal permeability assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Characterization of jejunal absorption and apical efflux of ropivacaine, lidocaine and bupivacaine in the rat using in situ and in vitro absorption models

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Predicting drug absorption: how nature made it a difficult problem.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Prediction of intestinal permeability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Assessing the absorption of new pharmaceuticals

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Strategies for absorption screening in drug discovery and development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Caco-2 monolayers in experimental and theoretical predictions of drug transport

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Cell cultures as tools in biopharmacy.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Comparison between permeability coefficients in rat and human jejunum

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Biopharmaceutics classification system: validation and learnings of an in vitro permeability assay

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Exploring the role of different drug transport routes in permeability screening.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

In vitro systems for studying intestinal drug absorption

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

MDCK (Madin-Darby canine kidney) cells: A tool for membrane permeability screening

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

General principles in the characterization and use of model systems for biopharmaceutical studies.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Development and evaluation of an in vitro method for prediction of human drug absorption II. Demonstration of the method suitability.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Membrane transport of drugs in different regions of the intestinal tract of the rat.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

The utility of rat jejunal permeability for biopharmaceutics classification system.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Development and evaluation of an in vitro method for prediction of human drug absorption I. Assessment of artificial membrane composition.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Drug permeability across a phospholipid vesicle based barrier: a novel approach for studying passive diffusion.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Effect of experimental pH on the in vitro permeability in intact rabbit intestines and Caco-2 monolayer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Permeability classification of representative fluoroquinolones by a cell culture method

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Validation of cell culture models for the intestine and the blood-brain barrier and comparison of drug permeation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Development of a 7-day, 96-well Caco-2 permeability assay with high-throughput direct UV compound analysis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Implementation of the caco-2 cell culture model as a predictive tool for the oral absorption of drugs. In-house evaluation procedures

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Correlating partitioning and caco-2 cell permeability of structurally diverse small molecular weight compounds.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Human jejunal effective permeability and its correlation with preclinical drug absorption models

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976984

Mucosal in vitro permeability in the intestinal tract of the pig, the rat, and man: species- and region-related differences

1 September 2018

1 reference

12 December 2020

Drug absorption. I. An in situ rat gut technique yielding realistic absorption rates

1 reference

12 December 2020

Predicting fraction dose absorbed in humans using a macroscopic mass balance approach

1 reference

12 December 2020

Regional intestinal permeability in rats of compounds with different physicochemical properties and transport mechanisms

1 reference

12 December 2020

Improved prediction of in vivo peroral absorption from in vitro intestinal permeability using an internal standard to control for intra- and inter-rat variability

1 reference

12 December 2020

Validation of a Caco-2 cell monolayer culture for drug transport studies

1 reference

12 December 2020

Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes

1 reference

12 December 2020

Absorption of drugs from the rat small intestine

1 reference

12 December 2020

Frog intestinal sac: a new in vitro method for the assessment of intestinal permeability

1 reference

12 December 2020

Development of a more rapid, reduced serum culture system for Caco-2 monolayers and application to the biopharmaceutics classification system

1 reference

12 December 2020

Prediction of human absorption of natural compounds by the non-everted rat intestinal sac model

1 reference

12 December 2020

Drug adsorption to plastic containers and retention of drugs in cultured cells under in vitro conditions

1 reference

12 December 2020

The suitability of an in situ perfusion model for permeability determinations: utility for BCS class I biowaiver requests

1 reference

12 December 2020

10.1208/S12248-010-9227-8

Identifiers

DOI

1 reference

PMCID

2976984

Dimensions Publication ID

23 August 2017

0 references

1 reference

23 August 2017

1 reference

PMCID

2976984