(Q37785857)

English

DNA methylation or histone modification status in metastasis and angiogenesis-related genes: a new hypothesis on usage of DNMT inhibitors and S-adenosylmethionine for genome stability

scientific article published on December 1, 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

DNA methylation or histone modification status in metastasis and angiogenesis-related genes: a new hypothesis on usage of DNMT inhibitors and S-adenosylmethionine for genome stability (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

DNA methylation

0 references

genome stability

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Mehmet Sahin

1

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

Emel Sahin

2

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

Saadet Gümüşlü

3

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

Abdullah Erdoğan

4

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

Meral Gültekin

5

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

language of work or name

1 reference

National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20821252

8 July 2024

publication date

1 December 2010

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

full work available at URL

http://link.springer.com/content/pdf/10.1007/s10555-010-9253-0.pdf

Portable Document Format

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

http://link.springer.com/article/10.1007/s10555-010-9253-0/fulltext.html

1 reference

10.1007/S10555-010-9253-0

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8 July 2024

http://link.springer.com/content/pdf/10.1007/s10555-010-9253-0

1 reference

10.1007/S10555-010-9253-0

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Cancer and Metastasis Reviews

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

29

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Europe PubMed Central

PubMed publication ID

23 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

655-676

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

CDH1 germline mutation in hereditary gastric carcinoma

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Inactivation of the E-cadherin-mediated cell adhesion system in human cancers

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Expression of thrombospondin-1 in ischemia-induced retinal neovascularization

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Aberrant CpG island methylation of multiple genes in intrahepatic cholangiocarcinoma

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DNA hypermethylation of TIMP3 gene in invasive breast ductal carcinoma

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The role of VHL in the regulation of E-cadherin: a new connection in an old pathway

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Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis

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Cell-Type-Specific Repression of the Maspin Gene Is Disrupted Frequently by Demethylation at the Promoter Region in Gastric Intestinal Metaplasia and Cancer Cells

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Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase

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Endothelial function in Marfan syndrome: selective impairment of flow-mediated vasodilation

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Epigenetic events in the colorectum and in colon cancer

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The mechanism of metastasis

1

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DNA methylation in cancer: too much, but also too little

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RNA and the epigenetic regulation of X chromosome inactivation

4

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Role for DNA methylation in genomic imprinting

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Impact of aging on DNA methylation

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DNA methylation and cancer therapy: new developments and expectations

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DNA methylation and cancer

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10.1007/S10555-010-9253-0

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DNA Methylation and Gene Function

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Angiostatic activity of DNA methyltransferase inhibitors

14

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Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

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10.1007/S10555-010-9253-0

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Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries

17

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Identification of Epigenetically Silenced Genes in Tumor Endothelial Cells

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A causal role for E-cadherin in the transition from adenoma to carcinoma

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E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases.

23

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E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity

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E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent Manner

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Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin

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Protein kinase D signaling

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117

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8 July 2024

The membrane-anchored matrix metalloproteinase (MMP) regulator RECK in combination with MMP-9 serves as an informative prognostic indicator for colorectal cancer

118

1 reference

10.1007/S10555-010-9253-0

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8 July 2024

Prognostic significance of reversion-inducing cysteine-rich protein with Kazal motifs expression in resected pathologic stage IIIA N2 non-small-cell lung cancer

119

1 reference

10.1007/S10555-010-9253-0

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8 July 2024

Correlation of reversion-inducing cysteine-rich protein with kazal motifs (RECK) and extracellular matrix metalloproteinase inducer (EMMPRIN), with MMP-2, MMP-9, and survival in colorectal cancer

120

1 reference

10.1007/S10555-010-9253-0

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8 July 2024

Epigenetic inactivation of the metastasis suppressor RECK enhances invasion of human colon cancer cells

121

1 reference

10.1007/S10555-010-9253-0

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8 July 2024

Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer

122

1 reference

10.1007/S10555-010-9253-0

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8 July 2024

Involvement of histone deacetylation in ras-induced down-regulation of the metastasis suppressor RECK.

124

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Silencing of the metastasis suppressor RECK by RAS oncogene is mediated by DNA methyltransferase 3b-induced promoter methylation

125

1 reference

10.1007/S10555-010-9253-0

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8 July 2024

International Journal of Oncology

127

18

71

author name string

SS Lakka

publication date

2001

1 reference

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8 July 2024

The American Journal of Pathology

129

138

1059

author name string

C Pyke

publication date

1991

1 reference

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8 July 2024

Immunocytochemical localization of urokinase-type plasminogen activator in Lewis lung carcinoma

130

1 reference

10.1007/S10555-010-9253-0

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8 July 2024

Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancer

132

1 reference

10.1007/S10555-010-9253-0

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8 July 2024

The American Journal of Pathology

134

147

114

author name string

DW Hsu

publication date

1995

1 reference

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8 July 2024

International Journal of Oncology

135

14

535

author name string

H Miyake

publication date

1999

1 reference

10.1007/S10555-010-9253-0

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8 July 2024

Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents

136

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis.

138

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Demethylation of urokinase promoter as a prognostic marker in patients with breast carcinoma.

139

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion

140

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo

141

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

The methyl donor S-Adenosylmethionine inhibits active demethylation of DNA: a candidate novel mechanism for the pharmacological effects of S-Adenosylmethionine

142

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis

143

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Antisense MBD2 gene therapy inhibits tumorigenesis

144

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Deficiency of Mbd2 suppresses intestinal tumorigenesis

145

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo.

146

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Expression of matrix metalloproteinases (MMP-2 and -9) and their inhibitors (TIMP-1 and -2) in prostate cancer tissue

147

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer

149

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Loss of epigenetic control of synuclein-gamma gene as a molecular indicator of metastasis in a wide range of human cancers

150

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.

151

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Discovery of aberrant expression of R-RAS by cancer-linked DNA hypomethylation in gastric cancer using microarrays

152

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Angiogenesis in life, disease and medicine

154

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling

155

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance.

156

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Cyclooxygenase-2 in cancer and angiogenesis

157

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

The histone deacetylase inhibitor NVP-LAQ824 inhibits angiogenesis and has a greater antitumor effect in combination with the vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584.

158

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165.

159

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide

160

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Nitric oxide synthase modulates angiogenesis in response to tissue ischemia

161

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Inhibitors of histone deacetylation downregulate the expression of endothelial nitric oxide synthase and compromise endothelial cell function in vasorelaxation and angiogenesis

163

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

164

3

46

author name string

DC Altieri

publication date

2003

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF.

165

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Lost in transcription: p21 repression, mechanisms, and consequences

166

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Protective mechanisms of p53-p21-pRb proteins against DNA damage-induced cell death

167

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications

168

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma.

169

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

170

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

171

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Rapid insulin-like growth factor (IGF)-independent effects of IGF binding protein-3 on endothelial cell survival

172

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Runx1 promotes angiogenesis by downregulation of insulin-like growth factor-binding protein-3.

173

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy

175

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression

176

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Methylation and silencing of the Thrombospondin-1 promoter in human cancer

177

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

JunB gene expression is inactivated by methylation in chronic myeloid leukemia

178

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Clusterin-mediated apoptosis is regulated by adenomatous polyposis coli and is p21 dependent but p53 independent.

179

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Clusterin inhibits apoptosis by interacting with activated Bax

180

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

The inhibition of angiogenesis by antisense oligonucleotides to clusterin

181

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Apolipoprotein J inhibits the migration and adhesion of endothelial cells.

182

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Synthesis and functional analyses of nuclear clusterin, a cell death protein

183

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Fibrillins 1 and 2 perform partially overlapping functions during aortic development

185

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

The quiescin Q6 gene (QSCN6) is a fusion of two ancient gene families: thioredoxin and ERV1.

187

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Cell growth inhibition and gene expression induced by the histone deacetylase inhibitor, trichostatin A, on human hepatoma cells

188

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Oncogenic HRAS suppresses clusterin expression through promoter hypermethylation.

189

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

190

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

191

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

192

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

DNA hypomethylation leads to elevated mutation rates

193

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

194

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Mechanisms of angiogenesis and their use in the inhibition of tumor growth and metastasis.

196

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

198

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

199

6

107

author name string

SB Baylin

publication date

2006

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Identifying DNA methylation biomarkers of cancer drug response

200

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Sequential 5-Aza-2 deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1.

201

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Interaction of 5-aza-2'-deoxycytidine and depsipeptide on antineoplastic activity and activation of 14-3-3sigma, E-cadherin and tissue inhibitor of metalloproteinase 3 expression in human breast carcinoma cells

202

1 reference

10.1007/S10555-010-9253-0

https://api.crossref.org/works/10.1007/S10555-010-9253-0

8 July 2024

Identifiers

10.1007/S10555-010-9253-0

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 August 2017

ResearchGate publication ID

0 references

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