(Q37789471)

23 August 2017

title

Maintenance of cellular tetrahydrobiopterin homeostasis (English)

1 reference

23 August 2017

1 reference

Hye-Lim Kim

1

1 reference

23 August 2017

Young Shik Park

2

1 reference

23 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20846489

14 July 2024

publication date

1 September 2010

1 reference

full work available at URL

23 August 2017

http://society.kisti.re.kr/sv/SV_svpsbs03V.do?method=download&cn1=JAKO201028552429147

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20846489

http://ocean.kisti.re.kr/downfile/crosscheck/ksbmb/JAKO201028552429147.pdf

14 July 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

14 July 2024

1 reference

23 August 2017

volume

43

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23 August 2017

issue

9

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23 August 2017

page(s)

584-592

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Tetrahydrobiopterin biosynthesis, regeneration and functions

23 August 2017

cites work

1

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Disorders of biopterin metabolism

14 July 2024

2

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

14 July 2024

3

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Examination of tetrahydrobiopterin pathway genes in autism

14 July 2024

4

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Analysis of plasma biopterin levels in psychiatric disorders suggests a common BH4 deficit in schizophrenia and schizoaffective disorder.

14 July 2024

5

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Tetrahydrobiopterin availability in Parkinson's and Alzheimer's disease; potential pathogenic mechanisms

14 July 2024

6

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Molecular mechanisms underlying the activation of eNOS.

14 July 2024

7

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Relationship between plasma and red cell biopterins in acute and chronic hyperphenylalaninaemia

14 July 2024

8

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction

14 July 2024

9

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide

14 July 2024

10

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters

14 July 2024

11

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Human carbonyl and aldose reductases: new catalytic functions in tetrahydrobiopterin biosynthesis.

14 July 2024

12

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues

14 July 2024

13

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Mutations in the sepiapterin reductase gene cause a novel tetrahydrobiopterin-dependent monoamine-neurotransmitter deficiency without hyperphenylalaninemia

14 July 2024

14

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Detection of sepiapterin in CSF of patients with sepiapterin reductase deficiency

14 July 2024

15

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

A murine model for human sepiapterin-reductase deficiency

14 July 2024

16

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Can the DCoHalpha isozyme compensate in patients with 4a-hydroxy-tetrahydrobiopterin dehydratase/DCoH deficiency?

14 July 2024

17

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Feedback regulation mechanisms for the control of GTP cyclohydrolase I activity

14 July 2024

18

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Decameric GTP cyclohydrolase I forms complexes with two pentameric GTP cyclohydrolase I feedback regulatory proteins in the presence of phenylalanine or of a combination of tetrahydrobiopterin and GTP

14 July 2024

19

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.

14 July 2024

20

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

14 July 2024

21

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Role of human GTP cyclohydrolase I and its regulatory protein in tetrahydrobiopterin metabolism

14 July 2024

22

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Regulation of tetrahydrobiopterin biosynthesis by shear stress

14 July 2024

23

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide

14 July 2024

24

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Intraplatelet tetrahydrobiopterin plays an important role in regulating canine coronary arterial thrombosis by modulating intraplatelet nitric oxide and superoxide generation

14 July 2024

25

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Protein Kinase C Phosphorylates and Activates GTP Cyclohydrolase I in Rat Renal Mesangial Cells

14 July 2024

26

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Phosphorylation of GTP cyclohydrolase I and modulation of its activity in rodent mast cells. GTP cyclohydrolase I hyperphosphorylation is coupled to high affinity IgE receptor signaling and involves protein kinase C.

14 July 2024

27

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Tetrahydrobiopterin, a Critical Factor in the Production and Role of Nitric Oxide in Mast Cells

14 July 2024

28

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Identification and functional characterization of phosphorylation sites on GTP cyclohydrolase I

14 July 2024

29

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

GTP cyclohydrolase feedback regulatory protein controls cofactor 6-tetrahydrobiopterin synthesis in the cytosol and in the nucleus of epidermal keratinocytes and melanocytes

14 July 2024

30

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus.

14 July 2024

31

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

In vivo activation of AMP-activated protein kinase attenuates diabetes-enhanced degradation of GTP cyclohydrolase I

14 July 2024

32

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Guanosine triphosphate cyclohydrolase I expression and enzymatic activity are present in caveolae of endothelial cells

14 July 2024

33

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Regulation of tetrahydrobiopterin synthesis and bioavailability in endothelial cells

14 July 2024

34

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Therapeutic potential of tetrahydrobiopterin for treating vascular and cardiac disease

14 July 2024

35

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Changes in tetrahydrobiopterin levels in endothelial cells and adult cardiomyocytes induced by LPS and hydrogen peroxide--a role for GFRP?

14 July 2024

36

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

GTP cyclohydrolase I inhibition by the prototypic inhibitor 2, 4-diamino-6-hydroxypyrimidine. Mechanisms and unanticipated role of GTP cyclohydrolase I feedback regulatory protein

14 July 2024

37

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytes

14 July 2024

38

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression

14 July 2024

39

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Critical role of interleukin-1beta for transcriptional regulation of endothelial 6-pyruvoyltetrahydropterin synthase

14 July 2024

40

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Prenatal diagnosis of "dihydrobiopterin synthetase" deficiency, a variant form of phenylketonuria

14 July 2024

41

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Sepiapterin reductase exhibits a NADPH-dependent dicarbonyl reductase activity

14 July 2024

42

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Dihydropteridine reductase deficiency in man: from biology to treatment

14 July 2024

43

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function.

14 July 2024

44

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Stoichiometric Arginine Binding in the Oxygenase Domain of Inducible Nitric Oxide Synthase Requires a Single Molecule of Tetrahydrobiopterin per Dimer

14 July 2024

45

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors

14 July 2024

46

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS.

14 July 2024

47

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Reaction of tetrahydrobiopterin with superoxide: EPR-kinetic analysis and characterization of the pteridine radical

14 July 2024

48

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Dose dependent effects of reactive oxygen and nitrogen species on the function of neuronal nitric oxide synthase

14 July 2024

49

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Reactive oxygen and nitrogen species regulate inducible nitric oxide synthase function shifting the balance of nitric oxide and superoxide production

14 July 2024

50

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Increased oxidative stress in lambs with increased pulmonary blood flow and pulmonary hypertension: role of NADPH oxidase and endothelial NO synthase

14 July 2024

51

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

The role of oxidative stress and NADPH oxidase in cerebrovascular disease

14 July 2024

52

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

The reaction of nitric oxide with organic peroxyl radicals

14 July 2024

53

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

The auto-oxidation of tetrahydrobiopterin

14 July 2024

54

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Possible involvement of hydroxyl radical on the stimulation of tetrahydrobiopterin synthesis by hydrogen peroxide and peroxynitrite in vascular endothelial cells

14 July 2024

55

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells.

14 July 2024

56

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through activation of the Jak2 tyrosine kinase pathway in vascular endothelial cells

14 July 2024

57

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Peroxynitrite induces destruction of the tetrahydrobiopterin and heme in endothelial nitric oxide synthase: transition from reversible to irreversible enzyme inhibition

14 July 2024

58

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Janus-faced role of endothelial NO synthase in vascular disease: uncoupling of oxygen reduction from NO synthesis and its pharmacological reversal

14 July 2024

59

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase

14 July 2024

60

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways

14 July 2024

61

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Diminished expression of dihydropteridine reductase is a potent biomarker for hypertensive vessels

14 July 2024

62

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Perturbed 6-tetrahydrobiopterin recycling via decreased dihydropteridine reductase in vitiligo: more evidence for H2O2 stress

14 July 2024

63

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Coronary endothelial dysfunction in the insulin-resistant state is linked to abnormal pteridine metabolism and vascular oxidative stress

14 July 2024

64

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Regulation of the Enzymes of the beta-Ketoadipate Pathway in Moraxella calcoacetica. 3. Effects of 3-Hydroxy-4-Methylbenzoate on the Synthesis of Enzymes of the Protocatechuate Branch

14 July 2024

65

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension

14 July 2024

66

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Pulmonary hypertension in a GTP-cyclohydrolase 1-deficient mouse

14 July 2024

67

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

Sepiapterin attenuates 1-methyl-4-phenylpyridinium-induced apoptosis in neuroblastoma cells transfected with neuronal NOS: role of tetrahydrobiopterin, nitric oxide, and proteasome activation

14 July 2024

68

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

The emerging role of neuronal nitric oxide synthase in the regulation of myocardial function

14 July 2024

69

1 reference

https://api.crossref.org/works/10.5483/BMBREP.2010.43.9.584

14 July 2024

Identifiers

1 reference

23 August 2017

1 reference