(Q37793795)

PubMed publication ID

20877225

23 August 2017

title

Transactivation of genes encoding for phase II enzymes and phase III transporters by phytochemical antioxidants (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257698&resulttype=core&format=json

13 May 2020

1 reference

Yoon Mee Yang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257698&resulttype=core&format=json

13 May 2020

Kyoung Noh

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257698&resulttype=core&format=json

13 May 2020

Chang Yeob Han

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257698&resulttype=core&format=json

13 May 2020

Sang Geon Kim

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257698&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

7 September 2010

1 reference

PubMed publication ID

23 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257698&resulttype=core&format=json

13 May 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257698&resulttype=core&format=json

13 May 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257698&resulttype=core&format=json

13 May 2020

page(s)

6332-6348

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257698&resulttype=core&format=json

Creative Commons Attribution 4.0 International

13 May 2020

copyright license

start time

7 September 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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Inhibition of osteoclast differentiation and bone resorption by sauchinone.

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p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens

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Chemopreventive activity of oltipraz.

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Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress

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Suppression of Th2-driven, allergen-induced airway inflammation by sauchinone

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Regulation of phase 2 enzyme induction by oltipraz and other dithiolethiones

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Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters

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Decreased activity and enhanced nuclear export of CCAAT-enhancer-binding protein beta during inhibition of adipogenesis by ceramide

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Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome

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Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport

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Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death.

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12 December 2020

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

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12 December 2020

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12 December 2020

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12 December 2020

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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12 December 2020

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12 December 2020

Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl isothiocyanate (PEITC)

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12 December 2020

Resveratrol-mediated reversal of doxorubicin resistance in acute myeloid leukemia cells via downregulation of MRP1 expression

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12 December 2020

Oltipraz: clinical opportunities for cancer chemoprevention. p.

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12 December 2020

Differential effects of the oxidized metabolites of oltipraz on the activation of CCAAT/enhancer binding protein-beta and NF-E2-related factor-2 for GSTA2 gene induction

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12 December 2020

Inhibition of LXRα-Dependent Steatosis and Oxidative Injury by Liquiritigenin, a Licorice Flavonoid, as Mediated with Nrf2 Activation

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12 December 2020

Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Effects of endocrine disruptors on genes associated with 17beta-estradiol metabolism and excretion.

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12 December 2020

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12 December 2020

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12 December 2020

Polymorphisms in the ABC drug transporter gene MDR1.

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12 December 2020

Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression

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12 December 2020

Interferon-gamma induces C/EBP beta expression and activity through MEK/ERK and p38 in T84 colon epithelial cells.

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12 December 2020

Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury.

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12 December 2020

Transactivation of the PPAR-responsive enhancer module in chemopreventive glutathione S-transferase gene by the peroxisome proliferator-activated receptor-gamma and retinoid X receptor heterodimer

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12 December 2020

Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NF-kappaB-dependent iNOS and proinflammatory cytokines production

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12 December 2020

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12 December 2020

Role of p90 ribosomal S6-kinase-1 in oltipraz-induced specific phosphorylation of CCAAT/enhancer binding protein-beta for GSTA2 gene transactivation

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12 December 2020

Liquiritigenin, a flavonoid aglycone from licorice, has a choleretic effect and the ability to induce hepatic transporters and phase-II enzymes

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12 December 2020

Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology

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12 December 2020

Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha

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12 December 2020

Intermittent dosing with oltipraz: relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases.

1 reference

12 December 2020

The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl CoA oxidase gene

1 reference

12 December 2020

Phase 2 enzyme induction by the major metabolite of oltipraz

1 reference

12 December 2020

LXRS and FXR: the yin and yang of cholesterol and fat metabolism

1 reference

12 December 2020

Alteration of xenobiotic metabolizing enzymes by resveratrol in liver and lung of CD1 mice.

1 reference

12 December 2020

Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor

1 reference

12 December 2020

Regulation of Drug Transporter Gene Expression by Nuclear Receptors

1 reference

12 December 2020

Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein beta activation in the induction of glutathione S-transferase by oltipraz

1 reference

12 December 2020

Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells

1 reference

12 December 2020

Insulin activates CCAAT/enhancer binding proteins and proinflammatory gene expression through the phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells

1 reference

12 December 2020

Regulation and interaction of pp90(rsk) isoforms with mitogen-activated protein kinases

1 reference

12 December 2020

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

1 reference

12 December 2020

The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes

1 reference

12 December 2020

Application of compartmental modeling to an examination of in vitro intestinal permeability data: assessing the impact of tissue uptake, P-glycoprotein, and CYP3A.

1 reference

12 December 2020

Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation

1 reference

12 December 2020

Lipopolysaccharide results in a marked decrease in hepatocyte nuclear factor 4 alpha in rat liver

1 reference

12 December 2020

CCAAT/enhancer-binding proteins: structure, function and regulation

1 reference

12 December 2020

Effect of dietary genistein on Phase II and antioxidant enzymes in rat liver

1 reference

12 December 2020

Regulation of glutathione S-transferase Ya subunit gene expression: identification of a unique xenobiotic-responsive element controlling inducible expression by planar aromatic compounds

1 reference

12 December 2020

Regulation of phase II enzymes by genistein and daidzein in male and female Swiss Webster mice

1 reference

12 December 2020

Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells

1 reference

12 December 2020

Peroxisome proliferator-activated receptor (PPAR) alpha and PPARbeta/delta, but not PPARgamma, modulate the expression of genes involved in cardiac lipid metabolism

1 reference

12 December 2020

Regulatory mechanisms of cellular response to oxidative stress

1 reference

12 December 2020

Molecular mechanisms of Nrf2-mediated antioxidant response

1 reference

12 December 2020

Ceramide down-regulates System A amino acid transport and protein synthesis in rat skeletal muscle cells.

1 reference

12 December 2020

Phase II enzyme induction by alpha-lipoic acid through phosphatidylinositol 3-kinase-dependent C/EBPs activation

1 reference

12 December 2020

Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals

1 reference

12 December 2020

Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism

1 reference

12 December 2020

Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.

1 reference

12 December 2020

Ceramide negatively regulates glutathione S-transferase gene transactivation via repression of hepatic nuclear factor-1 that is degraded by the ubiquitin proteasome system

1 reference

12 December 2020

A novel bile acid-activated vitamin D receptor signaling in human hepatocytes

1 reference

12 December 2020

Regulation of lipid and lipoprotein metabolism by PPAR activators

1 reference

12 December 2020

Fasting induces basolateral uptake transporters of the SLC family in the liver via HNF4alpha and PGC1alpha

1 reference

12 December 2020

Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis

1 reference

12 December 2020

Mechanism of rat UDP-glucuronosyltransferase 1A6 induction by oltipraz: evidence for a contribution of the Aryl hydrocarbon receptor pathway

1 reference

12 December 2020

Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes

1 reference

12 December 2020

The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability

1 reference

12 December 2020

FXR, a multipurpose nuclear receptor

1 reference

12 December 2020

HNF4: A central regulator of hepatocyte differentiation and function

1 reference

12 December 2020

MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma

1 reference

12 December 2020

Induction of nuclear transcription factors, cytochrome P450 monooxygenases, and glutathione S-transferase alpha gene expression in Aroclor 1254-treated rat hepatocyte cultures.

1 reference

12 December 2020

Signal transduction in the liver: C/EBPbeta modulates cell proliferation and survival

1 reference

12 December 2020

Ritonavir and dexamethasone induce expression of CYP3A and P-glycoprotein in rats

1 reference

12 December 2020

Localization and function of the organic anion-transporting polypeptide Oatp2 in rat liver

1 reference

12 December 2020

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

1 reference

12 December 2020

Nrf2-Keap1 defines a physiologically important stress response mechanism

1 reference

12 December 2020

Ceramide, an apoptotic rheostat, inhibits CCAAT/enhancer binding protein-beta and NF-E2-related factor-2 activation: the role in glutathione S-transferase A2 gene repression

1 reference

12 December 2020

Impact of drug transporter studies on drug discovery and development

1 reference

12 December 2020

Regulation of drug and bile salt transporters in liver and intestine

1 reference

12 December 2020

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

1 reference

12 December 2020

Role of hepatitis B virus X repression of C/EBPbeta activity in the down-regulation of glutathione S-transferase A2 gene: implications in other phase II detoxifying enzyme expression

1 reference

12 December 2020

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

1 reference

12 December 2020

Molecular mechanisms of natural products in chemoprevention: induction of cytoprotective enzymes by Nrf2.

1 reference

12 December 2020

10.3390/MOLECULES15096332

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257698&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257698&resulttype=core&format=json

13 May 2020

PubMed publication ID

20877225

1 reference