(Q37799098)

23 August 2017

Intrinsic cellular defense mechanisms targeting human cytomegalovirus (English)

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23 August 2017

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2

Thomas Stamminger

1 reference

23 August 2017

Nina Tavalai

1

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23 August 2017

8 October 2010

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23 August 2017

1 reference

23 August 2017

157

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23 August 2017

2

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23 August 2017

128-133

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Disruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PML

23 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Regulation of apoptosis by PML and the PML-NBs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Intrinsic immunity: a front-line defense against viral attack

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Deconstructing PML-induced premature senescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

PML residue lysine 160 is required for the degradation of PML induced by herpes simplex virus type 1 regulatory protein ICP0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Interaction between the human cytomegalovirus UL82 gene product (pp71) and hDaxx regulates immediate-early gene expression and viral replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Human cytomegalovirus (HCMV) UL82 gene product (pp71) relieves hDaxx-mediated repression of HCMV replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Recruitment of the histone methyltransferase SUV39H1 and its role in the oncogenic properties of the leukemia-associated PML-retinoic acid receptor fusion protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

PML nuclear bodies: dynamic sensors of DNA damage and cellular stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Differential relocation and stability of PML-body components during productive human cytomegalovirus infection: detailed characterization by live-cell imaging.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

PML and PML nuclear bodies: implications in antiviral defence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

HIV-1 Vif, APOBEC, and intrinsic immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Knockdown of hDaxx in normally non-permissive undifferentiated cells does not permit human cytomegalovirus immediate-early gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Lytic infection of permissive cells with human cytomegalovirus is regulated by an intrinsic 'pre-immediate-early' repression of viral gene expression mediated by histone post-translational modification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Functional interaction between the pp71 protein of human cytomegalovirus and the PML-interacting protein human Daxx

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Proteasome-dependent, ubiquitin-independent degradation of Daxx by the viral pp71 protein in human cytomegalovirus-infected cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Human cytomegalovirus protein pp71 induces Daxx SUMOylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Human cytomegalovirus immediate early interaction with host nuclear structures: definition of an immediate transcript environment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Daxx-mediated accumulation of human cytomegalovirus tegument protein pp71 at ND10 facilitates initiation of viral infection at these nuclear domains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Inhibition of SUMO-independent PML oligomerization by the human cytomegalovirus IE1 protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Proteasome inhibitor MG132 blocks viral DNA replication and assembly of human cytomegalovirus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

The nuclear domain 10 (ND10) is disrupted by the human cytomegalovirus gene product IE1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Ability of the human cytomegalovirus IE1 protein to modulate sumoylation of PML correlates with its functional activities in transcriptional regulation and infectivity in cultured fibroblast cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Human cytomegalovirus protein pp71 displaces the chromatin-associated factor ATRX from nuclear domain 10 at early stages of infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Activity and intracellular localization of the human cytomegalovirus protein pp71.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Nuclear domain 10, the site of DNA virus transcription and replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Nuclear domain 10 (ND10) associated proteins are also present in nuclear bodies and redistribute to hundreds of nuclear sites after stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Nuclear localization of tegument-delivered pp71 in human cytomegalovirus-infected cells is facilitated by one or more factors present in terminally differentiated fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Role of the cellular protein hDaxx in human cytomegalovirus immediate-early gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Analysis of latent viral gene expression in natural and experimental latency models of human cytomegalovirus and its correlation with histone modifications at a latent promoter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Latency, chromatin remodeling, and reactivation of human cytomegalovirus in the dendritic cells of healthy carriers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Human cytomegalovirus IE72 protein interacts with the transcriptional repressor hDaxx to regulate LUNA gene expression during lytic infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Pathogen subversion of cell-intrinsic innate immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Inactivating a cellular intrinsic immune defense mediated by Daxx is the mechanism through which the human cytomegalovirus pp71 protein stimulates viral immediate-early gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Human cytomegalovirus gene expression is silenced by Daxx-mediated intrinsic immune defense in model latent infections established in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Cellular and viral control over the initial events of human cytomegalovirus experimental latency in CD34+ cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Alpha interferon enhances TRIM5alpha-mediated antiviral activities in human and rhesus monkey cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

The role of PML in tumor suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Genome-wide screen of three herpesviruses for protein subcellular localization and alteration of PML nuclear bodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Human cytomegalovirus tegument proteins ppUL82 (pp71) and ppUL35 interact and cooperatively activate the major immediate-early enhancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

The mechanisms of PML-nuclear body formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Chromatin structure regulates human cytomegalovirus gene expression during latency, reactivation and lytic infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

PML nuclear bodies and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Host factors involved in resistance to retroviral infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Anti-viral protein APOBEC3G is induced by interferon-alpha stimulation in human hepatocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

New insights into the role of the subnuclear structure ND10 for viral infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Interplay between Herpesvirus Infection and Host Defense by PML Nuclear Bodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Evidence for a role of the cellular ND10 protein PML in mediating intrinsic immunity against human cytomegalovirus infections

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Nuclear domain 10 components promyelocytic leukemia protein and hDaxx independently contribute to an intrinsic antiviral defense against human cytomegalovirus infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

PML nuclear bodies as sites of epigenetic regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

SP100B is a repressor of gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

Proteasome-independent disruption of PML oncogenic domains (PODs), but not covalent modification by SUMO-1, is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

The transcriptional role of PML and the nuclear body

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.10.002

10.1016/J.VIRUSRES.2010.10.002

7 January 2021

Identifiers

DOI

1 reference

release_f6oxml5thnaa5czsdxucxy2n5m

23 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/f6oxml5thnaa5czsdxucxy2n5m

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

20934469

1 reference

PubMed ID

20934469