(Q37802185)

23 August 2017

title

Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress (English)

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23 August 2017

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4

S R Bornstein

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23 August 2017

K N Manolopoulos

1

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23 August 2017

L-O Klotz

series ordinal

2

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23 August 2017

P Korsten

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3

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23 August 2017

A Barthel

series ordinal

5

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23 August 2017

language of work or name

English

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publication date

1 November 2010

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23 August 2017

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23 August 2017

volume

15

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23 August 2017

issue

11

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23 August 2017

page(s)

1046-1052

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Risk of dementia in diabetes mellitus: a systematic review

23 August 2017

cites work

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Positive and negative regulation of insulin signaling by reactive oxygen and nitrogen species

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FoxO proteins in insulin action and metabolism

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Oxidative stress mediates tau-induced neurodegeneration in Drosophila

21 January 2018

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Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

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Hydrogen peroxide promotes Abeta production through JNK-dependent activation of gamma-secretase

21 January 2018

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Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia.

21 January 2018

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Lipid peroxidation in aging brain and Alzheimer's disease

21 January 2018

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The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation

21 January 2018

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Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases

21 January 2018

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Five years on the wings of fork head

21 January 2018

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Chromatin opening and stable perturbation of core histone:DNA contacts by FoxO1.

21 January 2018

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The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation

21 January 2018

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The FoxO transcription factors and metabolic regulation

21 January 2018

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FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics

21 January 2018

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Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2010.17

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2010.17

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2010.17

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2010.17

Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation

21 January 2018

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Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

21 January 2018

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Gone with the Wnts: beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2010.17

FOXO transcription factors in ageing and cancer.

21 January 2018

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Molecular mechanisms of insulin resistance

21 January 2018

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Novel concepts in insulin regulation of hepatic gluconeogenesis

21 January 2018

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New insights into structure and function of mitochondria and their role in aging and disease

21 January 2018

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Regulation and termination of NADPH oxidase activity

21 January 2018

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Phosphoinositide 3-kinase signaling in the cellular response to oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2010.17

Healthy aging: regulation of the metabolome by cellular redox modulation and prooxidant signaling systems: the essential roles of superoxide anion and hydrogen peroxide

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2010.17

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Stimulation of selenoprotein P promoter activity in hepatoma cells by FoxO1a transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Selenoprotein P expression is controlled through interaction of the coactivator PGC-1alpha with FoxO1a and hepatocyte nuclear factor 4alpha transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma expression, and diminished pro-osteogenic Wnt signaling in the skeleton

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2010.17

Functional interaction between beta-catenin and FOXO in oxidative stress signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Interaction of FOXO with beta-catenin inhibits beta-catenin/T cell factor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Regulation of pancreatic beta-cell function by the forkhead protein FoxO1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

The glamour and gloom of glycogen synthase kinase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Regulation and function of glycogen synthase kinase-3 isoforms in neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Co-localization of glycogen synthase kinase-3 with neurofibrillary tangles and granulovacuolar degeneration in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

The GSK3 hypothesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signaling cascades that induce glycogen synthase kinase-3 beta and a caspase-9-dependent apoptosis in cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Regulation of neuronal cell death by MST1-FOXO1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: a molecular mechanism leading to hepatic insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Insulin resistance and Alzheimer's disease: molecular links & clinical implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Caloric restriction and intermittent fasting: two potential diets for successful brain aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Pioglitazone improved cognition in a pilot study on patients with Alzheimer's disease and mild cognitive impairment with diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Increased Expression and Activity of the Transcription Factor FOXO1 in Nonalcoholic Steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

Oxidative alterations in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

7 January 2021

Molecular indices of oxidative stress and mitochondrial dysfunction occur early and often progress with severity of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

7 January 2021

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

7 January 2021

Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

7 January 2021

Association of selenoprotein p with Alzheimer's pathology in human cortex

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

7 January 2021

beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

7 January 2021

Stress-activated protein kinase/c-jun N-terminal kinase phosphorylates tau protein

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

7 January 2021

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

7 January 2021

Inflammation and NF-kappaB in Alzheimer's disease and diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2010.17

7 January 2021

Identifiers

DOI

10.1038/MP.2010.17

1 reference

Dimensions Publication ID

23 August 2017

1050805307

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1 reference